Seek and destroy: relating cancer drivers to therapies. Martinez-Ledesma, E., de Groot, J. F., & Verhaak, R. G. Cancer Cell, 27(3):319-21, 2015. 1878-3686 Martinez-Ledesma, Emmanuel de Groot, John F Verhaak, Roel G W P30 CA016672/CA/NCI NIH HHS/United States R01 CA190121/CA/NCI NIH HHS/United States U24 CA143883/CA/NCI NIH HHS/United States P50 CA127001/CA/NCI NIH HHS/United States P01 CA085878/CA/NCI NIH HHS/United States Comment Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't United States 2015/03/12 Cancer Cell. 2015 Mar 9;27(3):319-21. doi: 10.1016/j.ccell.2015.02.011.doi abstract bibtex In this issue of Cancer Cell, Rubio-Perez and colleagues present an in silico prescription strategy based on identifying somatic driver alterations and druggability options. Although relatively few patients were found treatable following current clinical guidelines, many more could benefit from drug repurposing, considering compounds at various stages of (pre-)clinical investigation.
@article{RN6146,
author = {Martinez-Ledesma, E. and de Groot, J. F. and Verhaak, R. G.},
title = {Seek and destroy: relating cancer drivers to therapies},
journal = {Cancer Cell},
volume = {27},
number = {3},
pages = {319-21},
note = {1878-3686
Martinez-Ledesma, Emmanuel
de Groot, John F
Verhaak, Roel G W
P30 CA016672/CA/NCI NIH HHS/United States
R01 CA190121/CA/NCI NIH HHS/United States
U24 CA143883/CA/NCI NIH HHS/United States
P50 CA127001/CA/NCI NIH HHS/United States
P01 CA085878/CA/NCI NIH HHS/United States
Comment
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
United States
2015/03/12
Cancer Cell. 2015 Mar 9;27(3):319-21. doi: 10.1016/j.ccell.2015.02.011.},
abstract = {In this issue of Cancer Cell, Rubio-Perez and colleagues present an in silico prescription strategy based on identifying somatic driver alterations and druggability options. Although relatively few patients were found treatable following current clinical guidelines, many more could benefit from drug repurposing, considering compounds at various stages of (pre-)clinical investigation.},
keywords = {Carcinogenesis/*genetics
*Decision Making, Computer-Assisted
Humans
Neoplasms/*genetics
Precision Medicine/*methods},
ISSN = {1535-6108},
DOI = {10.1016/j.ccell.2015.02.011},
year = {2015},
type = {Journal Article}
}
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