A provegetarian food pattern and reduction in total mortality in the Prevención con Dieta Mediterránea (PREDIMED) study

A provegetarian food pattern and reduction in total mortality in the Prevención con Dieta Mediterránea (PREDIMED) study. Martínez-González, M. A, Sánchez-Tainta, A., Corella, D., Salas-Salvadó, J., Ros, E., Arós, F., Gómez-Gracia, E., Fiol, M., Lamuela-Raventós, R. M, Schröder, H., Lapetra, J., Serra-Majem, L., Pinto, X., & Ruiz-Gutierrez, V. The American Journal of Clinical Nutrition, 100:320S–328S, July, 2014.

Paper doi abstract bibtex

Background: Vegetarian diets have been associated with reduced mortality. Because a pure vegetarian diet might not easily be embraced by many individuals, consuming preferentially plant-derived foods would be a more easily understood message. A provegetarian food pattern (FP) emphasizing preference for plant-derived foods might reduce all-cause mortality. Objective: The objective was to identify the association between an a priori–deﬁned provegetarian FP and all-cause mortality. Design: We followed 7216 participants (57% women; mean age: 67 y) at high cardiovascular risk for a median of 4.8 y. A validated 137-item semiquantitative food-frequency questionnaire was administered at baseline and yearly thereafter. Fruit, vegetables, nuts, cereals, legumes, olive oil, and potatoes were positively weighted. Added animal fats, eggs, ﬁsh, dairy products, and meats or meat products were negatively weighted. Energy-adjusted quintiles were used to assign points to build the provegetarian FP (range: 12–60 points). Deaths were conﬁrmed by review of medical records and the National Death Index. Results: There were 323 deaths during the follow-up period (76 from cardiovascular causes, 130 from cancer, 117 for noncancer, noncardiovascular causes). Higher baseline conformity with the provegetarian FP was associated with lower mortality (multivariableadjusted HR for $40 compared with ,30 points: 0.59; 95% CI: 0.40, 0.88). Similar results were found with the use of updated information on diet (RR: 0.59; 95% CI: 0.39, 0.89). Conclusions: Among omnivorous subjects at high cardiovascular risk, better conformity with an FP that emphasized plant-derived foods was associated with a reduced risk of all-cause mortality. This trial was registered at www.controlled-trials.com as ISRCTN35739639. Am J Clin Nutr 2014;100(suppl):320S–8S.

@article{martinez-gonzalez_provegetarian_2014,
	title = {A provegetarian food pattern and reduction in total mortality in the {Prevención} con {Dieta} {Mediterránea} ({PREDIMED}) study},
	volume = {100},
	issn = {00029165},
	url = {https://linkinghub.elsevier.com/retrieve/pii/S0002916523048773},
	doi = {10.3945/ajcn.113.071431},
	abstract = {Background: Vegetarian diets have been associated with reduced mortality. Because a pure vegetarian diet might not easily be embraced by many individuals, consuming preferentially plant-derived foods would be a more easily understood message. A provegetarian food pattern (FP) emphasizing preference for plant-derived foods might reduce all-cause mortality.
Objective: The objective was to identify the association between an a priori–deﬁned provegetarian FP and all-cause mortality. Design: We followed 7216 participants (57\% women; mean age: 67 y) at high cardiovascular risk for a median of 4.8 y. A validated 137-item semiquantitative food-frequency questionnaire was administered at baseline and yearly thereafter. Fruit, vegetables, nuts, cereals, legumes, olive oil, and potatoes were positively weighted. Added animal fats, eggs, ﬁsh, dairy products, and meats or meat products were negatively weighted. Energy-adjusted quintiles were used to assign points to build the provegetarian FP (range: 12–60 points). Deaths were conﬁrmed by review of medical records and the National Death Index.
Results: There were 323 deaths during the follow-up period (76 from cardiovascular causes, 130 from cancer, 117 for noncancer, noncardiovascular causes). Higher baseline conformity with the provegetarian FP was associated with lower mortality (multivariableadjusted HR for \$40 compared with ,30 points: 0.59; 95\% CI: 0.40, 0.88). Similar results were found with the use of updated information on diet (RR: 0.59; 95\% CI: 0.39, 0.89).
Conclusions: Among omnivorous subjects at high cardiovascular risk, better conformity with an FP that emphasized plant-derived foods was associated with a reduced risk of all-cause mortality. This trial was registered at www.controlled-trials.com as ISRCTN35739639. Am J Clin Nutr 2014;100(suppl):320S–8S.},
	language = {en},
	urldate = {2025-02-28},
	journal = {The American Journal of Clinical Nutrition},
	author = {Martínez-González, Miguel A and Sánchez-Tainta, Ana and Corella, Dolores and Salas-Salvadó, Jordi and Ros, Emilio and Arós, Fernando and Gómez-Gracia, Enrique and Fiol, Miquel and Lamuela-Raventós, Rosa M and Schröder, Helmut and Lapetra, Jose and Serra-Majem, Lluis and Pinto, Xavier and Ruiz-Gutierrez, Valentina},
	month = jul,
	year = {2014},
	pages = {320S--328S},
}

Downloads: 0

{"_id":"AYsRudYhcwNZfbG3X","bibbaseid":"martnezgonzlez-sncheztainta-corella-salassalvad-ros-ars-gmezgracia-fiol-etal-aprovegetarianfoodpatternandreductionintotalmortalityintheprevencincondietamediterrneapredimedstudy-2014","author_short":["Martínez-González, M. A","Sánchez-Tainta, A.","Corella, D.","Salas-Salvadó, J.","Ros, E.","Arós, F.","Gómez-Gracia, E.","Fiol, M.","Lamuela-Raventós, R. M","Schröder, H.","Lapetra, J.","Serra-Majem, L.","Pinto, X.","Ruiz-Gutierrez, V."],"bibdata":{"bibtype":"article","type":"article","title":"A provegetarian food pattern and reduction in total mortality in the Prevención con Dieta Mediterránea (PREDIMED) study","volume":"100","issn":"00029165","url":"https://linkinghub.elsevier.com/retrieve/pii/S0002916523048773","doi":"10.3945/ajcn.113.071431","abstract":"Background: Vegetarian diets have been associated with reduced mortality. Because a pure vegetarian diet might not easily be embraced by many individuals, consuming preferentially plant-derived foods would be a more easily understood message. A provegetarian food pattern (FP) emphasizing preference for plant-derived foods might reduce all-cause mortality. Objective: The objective was to identify the association between an a priori–deﬁned provegetarian FP and all-cause mortality. Design: We followed 7216 participants (57% women; mean age: 67 y) at high cardiovascular risk for a median of 4.8 y. A validated 137-item semiquantitative food-frequency questionnaire was administered at baseline and yearly thereafter. Fruit, vegetables, nuts, cereals, legumes, olive oil, and potatoes were positively weighted. Added animal fats, eggs, ﬁsh, dairy products, and meats or meat products were negatively weighted. Energy-adjusted quintiles were used to assign points to build the provegetarian FP (range: 12–60 points). Deaths were conﬁrmed by review of medical records and the National Death Index. Results: There were 323 deaths during the follow-up period (76 from cardiovascular causes, 130 from cancer, 117 for noncancer, noncardiovascular causes). Higher baseline conformity with the provegetarian FP was associated with lower mortality (multivariableadjusted HR for $40 compared with ,30 points: 0.59; 95% CI: 0.40, 0.88). Similar results were found with the use of updated information on diet (RR: 0.59; 95% CI: 0.39, 0.89). Conclusions: Among omnivorous subjects at high cardiovascular risk, better conformity with an FP that emphasized plant-derived foods was associated with a reduced risk of all-cause mortality. This trial was registered at www.controlled-trials.com as ISRCTN35739639. Am J Clin Nutr 2014;100(suppl):320S–8S.","language":"en","urldate":"2025-02-28","journal":"The American Journal of Clinical Nutrition","author":[{"propositions":[],"lastnames":["Martínez-González"],"firstnames":["Miguel","A"],"suffixes":[]},{"propositions":[],"lastnames":["Sánchez-Tainta"],"firstnames":["Ana"],"suffixes":[]},{"propositions":[],"lastnames":["Corella"],"firstnames":["Dolores"],"suffixes":[]},{"propositions":[],"lastnames":["Salas-Salvadó"],"firstnames":["Jordi"],"suffixes":[]},{"propositions":[],"lastnames":["Ros"],"firstnames":["Emilio"],"suffixes":[]},{"propositions":[],"lastnames":["Arós"],"firstnames":["Fernando"],"suffixes":[]},{"propositions":[],"lastnames":["Gómez-Gracia"],"firstnames":["Enrique"],"suffixes":[]},{"propositions":[],"lastnames":["Fiol"],"firstnames":["Miquel"],"suffixes":[]},{"propositions":[],"lastnames":["Lamuela-Raventós"],"firstnames":["Rosa","M"],"suffixes":[]},{"propositions":[],"lastnames":["Schröder"],"firstnames":["Helmut"],"suffixes":[]},{"propositions":[],"lastnames":["Lapetra"],"firstnames":["Jose"],"suffixes":[]},{"propositions":[],"lastnames":["Serra-Majem"],"firstnames":["Lluis"],"suffixes":[]},{"propositions":[],"lastnames":["Pinto"],"firstnames":["Xavier"],"suffixes":[]},{"propositions":[],"lastnames":["Ruiz-Gutierrez"],"firstnames":["Valentina"],"suffixes":[]}],"month":"July","year":"2014","pages":"320S–328S","bibtex":"@article{martinez-gonzalez_provegetarian_2014,\n\ttitle = {A provegetarian food pattern and reduction in total mortality in the {Prevención} con {Dieta} {Mediterránea} ({PREDIMED}) study},\n\tvolume = {100},\n\tissn = {00029165},\n\turl = {https://linkinghub.elsevier.com/retrieve/pii/S0002916523048773},\n\tdoi = {10.3945/ajcn.113.071431},\n\tabstract = {Background: Vegetarian diets have been associated with reduced mortality. Because a pure vegetarian diet might not easily be embraced by many individuals, consuming preferentially plant-derived foods would be a more easily understood message. A provegetarian food pattern (FP) emphasizing preference for plant-derived foods might reduce all-cause mortality.\nObjective: The objective was to identify the association between an a priori–deﬁned provegetarian FP and all-cause mortality. Design: We followed 7216 participants (57\\% women; mean age: 67 y) at high cardiovascular risk for a median of 4.8 y. A validated 137-item semiquantitative food-frequency questionnaire was administered at baseline and yearly thereafter. Fruit, vegetables, nuts, cereals, legumes, olive oil, and potatoes were positively weighted. Added animal fats, eggs, ﬁsh, dairy products, and meats or meat products were negatively weighted. Energy-adjusted quintiles were used to assign points to build the provegetarian FP (range: 12–60 points). Deaths were conﬁrmed by review of medical records and the National Death Index.\nResults: There were 323 deaths during the follow-up period (76 from cardiovascular causes, 130 from cancer, 117 for noncancer, noncardiovascular causes). Higher baseline conformity with the provegetarian FP was associated with lower mortality (multivariableadjusted HR for \\$40 compared with ,30 points: 0.59; 95\\% CI: 0.40, 0.88). Similar results were found with the use of updated information on diet (RR: 0.59; 95\\% CI: 0.39, 0.89).\nConclusions: Among omnivorous subjects at high cardiovascular risk, better conformity with an FP that emphasized plant-derived foods was associated with a reduced risk of all-cause mortality. This trial was registered at www.controlled-trials.com as ISRCTN35739639. Am J Clin Nutr 2014;100(suppl):320S–8S.},\n\tlanguage = {en},\n\turldate = {2025-02-28},\n\tjournal = {The American Journal of Clinical Nutrition},\n\tauthor = {Martínez-González, Miguel A and Sánchez-Tainta, Ana and Corella, Dolores and Salas-Salvadó, Jordi and Ros, Emilio and Arós, Fernando and Gómez-Gracia, Enrique and Fiol, Miquel and Lamuela-Raventós, Rosa M and Schröder, Helmut and Lapetra, Jose and Serra-Majem, Lluis and Pinto, Xavier and Ruiz-Gutierrez, Valentina},\n\tmonth = jul,\n\tyear = {2014},\n\tpages = {320S--328S},\n}\n\n\n\n\n\n\n\n\n\n\n\n","author_short":["Martínez-González, M. A","Sánchez-Tainta, A.","Corella, D.","Salas-Salvadó, J.","Ros, E.","Arós, F.","Gómez-Gracia, E.","Fiol, M.","Lamuela-Raventós, R. M","Schröder, H.","Lapetra, J.","Serra-Majem, L.","Pinto, X.","Ruiz-Gutierrez, V."],"key":"martinez-gonzalez_provegetarian_2014","id":"martinez-gonzalez_provegetarian_2014","bibbaseid":"martnezgonzlez-sncheztainta-corella-salassalvad-ros-ars-gmezgracia-fiol-etal-aprovegetarianfoodpatternandreductionintotalmortalityintheprevencincondietamediterrneapredimedstudy-2014","role":"author","urls":{"Paper":"https://linkinghub.elsevier.com/retrieve/pii/S0002916523048773"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero-group/nmyhill/5868189","dataSources":["Pu9hAwb4etNrzg8Xb"],"keywords":[],"search_terms":["provegetarian","food","pattern","reduction","total","mortality","prevenci","con","dieta","mediterr","nea","predimed","study","martínez-gonzález","sánchez-tainta","corella","salas-salvadó","ros","arós","gómez-gracia","fiol","lamuela-raventós","schröder","lapetra","serra-majem","pinto","ruiz-gutierrez"],"title":"A provegetarian food pattern and reduction in total mortality in the Prevención con Dieta Mediterránea (PREDIMED) study","year":2014}