Genealogical reconstruction of myotonic dystrophy in the Saguenay-Lac-Saint-Jean area (Quebec, Canada). Mathieu, J., De Braekeleer, M., & Prevost, C. Neurology, 40(5):839-42., 1990.
abstract   bibtex   
The prevalence of myotonic dystrophy (MyD) in the Saguenay-Lac-Saint-Jean (SLSJ) region (Quebec, Canada) is 30 to 60 times the world's prevalence. We identified 746 patients (673 still alive) distributed in 88 families. Using a population-based register of the SLSJ area and several marriage repositories from northeastern Quebec, we could trace back all patients to a couple who settled in "Nouvelle-France" in 1657. The MyD gene was then passed on over 10 to 14 generations. This genealogical reconstruction is a strong argument in favor of the genetic homogeneity of MyD in the SLSJ region.
@article{
 title = {Genealogical reconstruction of myotonic dystrophy in the Saguenay-Lac-Saint-Jean area (Quebec, Canada)},
 type = {article},
 year = {1990},
 identifiers = {[object Object]},
 keywords = {Female,Human,Male,Myotonic Dystrophy/epidemiology/*genetics,Pedigree,Prevalence,Quebec/epidemiology,Questionnaires,Support, Non-U.S. Gov't},
 pages = {839-42.},
 volume = {40},
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 abstract = {The prevalence of myotonic dystrophy (MyD) in the Saguenay-Lac-Saint-Jean (SLSJ) region (Quebec, Canada) is 30 to 60 times the world's prevalence. We identified 746 patients (673 still alive) distributed in 88 families. Using a population-based register of the SLSJ area and several marriage repositories from northeastern Quebec, we could trace back all patients to a couple who settled in "Nouvelle-France" in 1657. The MyD gene was then passed on over 10 to 14 generations. This genealogical reconstruction is a strong argument in favor of the genetic homogeneity of MyD in the SLSJ region.},
 bibtype = {article},
 author = {Mathieu, J and De Braekeleer, M and Prevost, C},
 journal = {Neurology},
 number = {5}
}
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