Lymphedema Secondary to Postmastectomy Radiation: Incidence and Risk Factors. Md, C. S. H., Mpa, N. L. W., Md, H. R., William Giese MD, J. D., Md, T. H., Kathleen A. Fassl PT, B. S., & Md, S. B. E. Annals of Surgical Oncology, 11(6):573--580, June, 2004. ![Lymphedema Secondary to Postmastectomy Radiation: Incidence and Risk Factors [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Background Postmastectomy radiotherapy (PMRT) has proven benefits for certain patients with breast cancer; however, one of its complications is lymphedema. This study examines the incidence of and risk factors associated with lymphedema secondary to PMRT. Methods The charts of patients treated with mastectomy at Roswell Park Cancer Institute between January 1, 1995, and April 20, 2001, who received PMRT were reviewed. Univariate analysis of patient, disease, and treatment variables was conducted. Multivariate analysis was performed on variables found to be significant in univariate analysis. Results One hundred five patients received PMRT. The incidence of lymphedema was 27%. Patient age, body mass index, disease stage, positive lymph nodes, nodes resected, postoperative infection, duration of drainage, chemotherapy, and hormonal therapy were not associated with lymphedema. Total dose (P = .032), posterior axillary boost (P = .047), overlap technique (P = .037), radiotherapy before 1999 (P = .028), and radiotherapy at Roswell Park Cancer Institute (P = .028) were significantly associated with lymphedema. Increased lymphedema was noted with supraclavicular, internal mammary, mastectomy scar boost, and chest wall tangential photon beam radiation, but the associations were not statistically significant. Conclusions The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT. Efforts to prevent lymphedema should be emphasized.
@article{md_lymphedema_2004,
title = {Lymphedema {Secondary} to {Postmastectomy} {Radiation}: {Incidence} and {Risk} {Factors}},
volume = {11},
issn = {1068-9265, 1534-4681},
shorttitle = {Lymphedema {Secondary} to {Postmastectomy} {Radiation}},
url = {http://link.springer.com/article/10.1245/ASO.2004.04.017},
doi = {10.1245/ASO.2004.04.017},
abstract = {Background Postmastectomy radiotherapy (PMRT) has proven benefits for certain patients with breast cancer; however, one of its complications is lymphedema. This study examines the incidence of and risk factors associated with lymphedema secondary to PMRT. Methods The charts of patients treated with mastectomy at Roswell Park Cancer Institute between January 1, 1995, and April 20, 2001, who received PMRT were reviewed. Univariate analysis of patient, disease, and treatment variables was conducted. Multivariate analysis was performed on variables found to be significant in univariate analysis. Results One hundred five patients received PMRT. The incidence of lymphedema was 27\%. Patient age, body mass index, disease stage, positive lymph nodes, nodes resected, postoperative infection, duration of drainage, chemotherapy, and hormonal therapy were not associated with lymphedema. Total dose (P = .032), posterior axillary boost (P = .047), overlap technique (P = .037), radiotherapy before 1999 (P = .028), and radiotherapy at Roswell Park Cancer Institute (P = .028) were significantly associated with lymphedema. Increased lymphedema was noted with supraclavicular, internal mammary, mastectomy scar boost, and chest wall tangential photon beam radiation, but the associations were not statistically significant. Conclusions The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT. Efforts to prevent lymphedema should be emphasized.},
language = {en},
number = {6},
urldate = {2013-06-30},
journal = {Annals of Surgical Oncology},
author = {Md, Christian S. Hinrichs and Mpa, Nancy L. Watroba and Md, Hamed Rezaishiraz and William Giese MD, J. D. and Md, Thelma Hurd and Kathleen A. Fassl PT, B. S. and Md, Stephen B. Edge},
month = jun,
year = {2004},
keywords = {Breast Neoplasms, Complications, Female, Humans, Incidence, Lymphedema, Middle Aged, Multivariate Analysis, New York, Oncology, Postmastectomy radiation, Radiotherapy, Adjuvant, Retrospective Studies, Risk Factors, Surgery, Surgical Oncology},
pages = {573--580},
file = {10.1245_ASO.2004.04.017.pdf:files/46619/10.1245_ASO.2004.04.017.pdf:application/pdf;10.1245_ASO.2004.04.017.pdf:files/46700/10.1245_ASO.2004.04.017.pdf:application/pdf}
}
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{"_id":"6QGDAKeX3J4TRdPvG","bibbaseid":"md-mpa-md-williamgiesemd-md-kathleenafasslpt-md-lymphedemasecondarytopostmastectomyradiationincidenceandriskfactors-2004","downloads":0,"creationDate":"2016-09-09T06:27:32.155Z","title":"Lymphedema Secondary to Postmastectomy Radiation: Incidence and Risk Factors","author_short":["Md, C. S. H.","Mpa, N. L. W.","Md, H. R.","William Giese MD, J. D.","Md, T. H.","Kathleen A. Fassl PT, B. S.","Md, S. B. E."],"year":2004,"bibtype":"article","biburl":"https://www.sfu.ca/~howlett/howlett16.bib","bibdata":{"bibtype":"article","type":"article","title":"Lymphedema Secondary to Postmastectomy Radiation: Incidence and Risk Factors","volume":"11","issn":"1068-9265, 1534-4681","shorttitle":"Lymphedema Secondary to Postmastectomy Radiation","url":"http://link.springer.com/article/10.1245/ASO.2004.04.017","doi":"10.1245/ASO.2004.04.017","abstract":"Background Postmastectomy radiotherapy (PMRT) has proven benefits for certain patients with breast cancer; however, one of its complications is lymphedema. This study examines the incidence of and risk factors associated with lymphedema secondary to PMRT. Methods The charts of patients treated with mastectomy at Roswell Park Cancer Institute between January 1, 1995, and April 20, 2001, who received PMRT were reviewed. Univariate analysis of patient, disease, and treatment variables was conducted. Multivariate analysis was performed on variables found to be significant in univariate analysis. Results One hundred five patients received PMRT. The incidence of lymphedema was 27%. Patient age, body mass index, disease stage, positive lymph nodes, nodes resected, postoperative infection, duration of drainage, chemotherapy, and hormonal therapy were not associated with lymphedema. Total dose (P = .032), posterior axillary boost (P = .047), overlap technique (P = .037), radiotherapy before 1999 (P = .028), and radiotherapy at Roswell Park Cancer Institute (P = .028) were significantly associated with lymphedema. Increased lymphedema was noted with supraclavicular, internal mammary, mastectomy scar boost, and chest wall tangential photon beam radiation, but the associations were not statistically significant. Conclusions The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT. Efforts to prevent lymphedema should be emphasized.","language":"en","number":"6","urldate":"2013-06-30","journal":"Annals of Surgical Oncology","author":[{"propositions":[],"lastnames":["Md"],"firstnames":["Christian","S.","Hinrichs"],"suffixes":[]},{"propositions":[],"lastnames":["Mpa"],"firstnames":["Nancy","L.","Watroba"],"suffixes":[]},{"propositions":[],"lastnames":["Md"],"firstnames":["Hamed","Rezaishiraz"],"suffixes":[]},{"propositions":[],"lastnames":["William","Giese","MD"],"firstnames":["J.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Md"],"firstnames":["Thelma","Hurd"],"suffixes":[]},{"propositions":[],"lastnames":["Kathleen","A.","Fassl","PT"],"firstnames":["B.","S."],"suffixes":[]},{"propositions":[],"lastnames":["Md"],"firstnames":["Stephen","B.","Edge"],"suffixes":[]}],"month":"June","year":"2004","keywords":"Breast Neoplasms, Complications, Female, Humans, Incidence, Lymphedema, Middle Aged, Multivariate Analysis, New York, Oncology, Postmastectomy radiation, Radiotherapy, Adjuvant, Retrospective Studies, Risk Factors, Surgery, Surgical Oncology","pages":"573--580","file":"10.1245_ASO.2004.04.017.pdf:files/46619/10.1245_ASO.2004.04.017.pdf:application/pdf;10.1245_ASO.2004.04.017.pdf:files/46700/10.1245_ASO.2004.04.017.pdf:application/pdf","bibtex":"@article{md_lymphedema_2004,\n\ttitle = {Lymphedema {Secondary} to {Postmastectomy} {Radiation}: {Incidence} and {Risk} {Factors}},\n\tvolume = {11},\n\tissn = {1068-9265, 1534-4681},\n\tshorttitle = {Lymphedema {Secondary} to {Postmastectomy} {Radiation}},\n\turl = {http://link.springer.com/article/10.1245/ASO.2004.04.017},\n\tdoi = {10.1245/ASO.2004.04.017},\n\tabstract = {Background Postmastectomy radiotherapy (PMRT) has proven benefits for certain patients with breast cancer; however, one of its complications is lymphedema. This study examines the incidence of and risk factors associated with lymphedema secondary to PMRT. Methods The charts of patients treated with mastectomy at Roswell Park Cancer Institute between January 1, 1995, and April 20, 2001, who received PMRT were reviewed. Univariate analysis of patient, disease, and treatment variables was conducted. Multivariate analysis was performed on variables found to be significant in univariate analysis. Results One hundred five patients received PMRT. The incidence of lymphedema was 27\\%. Patient age, body mass index, disease stage, positive lymph nodes, nodes resected, postoperative infection, duration of drainage, chemotherapy, and hormonal therapy were not associated with lymphedema. Total dose (P = .032), posterior axillary boost (P = .047), overlap technique (P = .037), radiotherapy before 1999 (P = .028), and radiotherapy at Roswell Park Cancer Institute (P = .028) were significantly associated with lymphedema. Increased lymphedema was noted with supraclavicular, internal mammary, mastectomy scar boost, and chest wall tangential photon beam radiation, but the associations were not statistically significant. Conclusions The high incidence and debilitating effects of lymphedema must be weighed against the benefits of PMRT. Efforts to prevent lymphedema should be emphasized.},\n\tlanguage = {en},\n\tnumber = {6},\n\turldate = {2013-06-30},\n\tjournal = {Annals of Surgical Oncology},\n\tauthor = {Md, Christian S. Hinrichs and Mpa, Nancy L. Watroba and Md, Hamed Rezaishiraz and William Giese MD, J. D. and Md, Thelma Hurd and Kathleen A. Fassl PT, B. S. and Md, Stephen B. Edge},\n\tmonth = jun,\n\tyear = {2004},\n\tkeywords = {Breast Neoplasms, Complications, Female, Humans, Incidence, Lymphedema, Middle Aged, Multivariate Analysis, New York, Oncology, Postmastectomy radiation, Radiotherapy, Adjuvant, Retrospective Studies, Risk Factors, Surgery, Surgical Oncology},\n\tpages = {573--580},\n\tfile = {10.1245_ASO.2004.04.017.pdf:files/46619/10.1245_ASO.2004.04.017.pdf:application/pdf;10.1245_ASO.2004.04.017.pdf:files/46700/10.1245_ASO.2004.04.017.pdf:application/pdf}\n}\n\n","author_short":["Md, C. S. H.","Mpa, N. L. W.","Md, H. R.","William Giese MD, J. D.","Md, T. H.","Kathleen A. Fassl PT, B. S.","Md, S. B. 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