Minimum Information about a Biosynthetic Gene cluster.

Minimum Information about a Biosynthetic Gene cluster. Medema, M. H., Kottmann, R., Yilmaz, P., Cummings, M., Biggins, J. B., Blin, K., de Bruijn , I., Chooi, Y. H., Claesen, J., Coates, R C., Cruz-Morales, P., Duddela, S., Düsterhus, S., Edwards, D. J., Fewer, D. P., Garg, N., Geiger, C., Gomez-Escribano, J. P., Greule, A., Hadjithomas, M., Haines, A. S., Helfrich, E. J N., Hillwig, M. L., Ishida, K., Jones, A. C., Jones, C. S., Jungmann, K., Kegler, C., Kim, H. U., Kötter, P., Krug, D., Masschelein, J., Melnik, A. V., Mantovani, S. M., Monroe, E. A., Moore, M., Moss, N., Nützmann, H., Pan, G., Pati, A., Petras, D., Reen, F J., Rosconi, F., Rui, Z., Tian, Z., Tobias, N. J., Tsunematsu, Y., Wiemann, P., Wyckoff, E., Yan, X., Yim, G., Yu, F., Xie, Y., Aigle, B., Apel, A. K., Balibar, C. J., Balskus, E. P., Barona-Gómez, F., Bechthold, A., Bode, H. B., Borriss, R., Brady, S. F., Brakhage, A. A., Caffrey, P., Cheng, Y., Clardy, J., Cox, R. J., De Mot, R., Donadio, S., Donia, M. S., van der Donk , W. A., Dorrestein, P. C., Doyle, S., Driessen, A. J M., Ehling-Schulz, M., Entian, K., Fischbach, M. A., Gerwick, L., Gerwick, W. H., Gross, H., Gust, B., Hertweck, C., Höfte, M., Jensen, S. E., Ju, J., Katz, L., Kaysser, L., Klassen, J. L., Keller, N. P., Kormanec, J., Kuipers, O. P., Kuzuyama, T., Kyrpides, N. C., Kwon, H., Lautru, S., Lavigne, R., Lee, C. Y., Linquan, B., Liu, X., Liu, W., Luzhetskyy, A., Mahmud, T., Mast, Y., Méndez, C., Metsä-Ketelä, M., Micklefield, J., Mitchell, D. A., Moore, B. S., Moreira, L. M., Müller, R., Neilan, B. A., Nett, M., Nielsen, J., O'Gara, F., Oikawa, H., Osbourn, A., Osburne, M. S., Ostash, B., Payne, S. M., Pernodet, J., Petricek, M., Piel, J., Ploux, O., Raaijmakers, J. M., Salas, J. A., Schmitt, E. K., Scott, B., Seipke, R. F., Shen, B., Sherman, D. H., Sivonen, K., Smanski, M. J., Sosio, M., Stegmann, E., Süssmuth, R. D., Tahlan, K., Thomas, C. M., Tang, Y., Truman, A. W., Viaud, M., Walton, J. D., Walsh, C. T., Weber, T., van Wezel , G. P., Wilkinson, B., Willey, J. M., Wohlleben, W., Wright, G. D., Ziemert, N., Zhang, C., Zotchev, S. B., Breitling, R., Takano, E., & Glöckner, F. O. Nat Chem Biol, 11(9):625–631, 2015.
doi abstract bibtex

A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

@Article{medema15minimum,
  author    = {Medema, Marnix H. and Kottmann, Renzo and Yilmaz, Pelin and Cummings, Matthew and Biggins, John B. and Blin, Kai and {de Bruijn}, Irene and Chooi, Yit Heng and Claesen, Jan and Coates, R Cameron and Cruz-Morales, Pablo and Duddela, Srikanth and D{\"{u}}sterhus, Stephanie and Edwards, Daniel J. and Fewer, David P. and Garg, Neha and Geiger, Christoph and Gomez-Escribano, Juan Pablo and Greule, Anja and Hadjithomas, Michalis and Haines, Anthony S. and Helfrich, Eric J N. and Hillwig, Matthew L. and Ishida, Keishi and Jones, Adam C. and Jones, Carla S. and Jungmann, Katrin and Kegler, Carsten and Kim, Hyun Uk and K{\"{o}}tter, Peter and Krug, Daniel and Masschelein, Joleen and Melnik, Alexey V. and Mantovani, Simone M. and Monroe, Emily A. and Moore, Marcus and Moss, Nathan and N{\"{u}}tzmann, Hans-Wilhelm and Pan, Guohui and Pati, Amrita and Petras, Daniel and Reen, F Jerry and Rosconi, Federico and Rui, Zhe and Tian, Zhenhua and Tobias, Nicholas J. and Tsunematsu, Yuta and Wiemann, Philipp and Wyckoff, Elizabeth and Yan, Xiaohui and Yim, Grace and Yu, Fengan and Xie, Yunchang and Aigle, Bertrand and Apel, Alexander K. and Balibar, Carl J. and Balskus, Emily P. and Barona-G{\'{o}}mez, Francisco and Bechthold, Andreas and Bode, Helge B. and Borriss, Rainer and Brady, Sean F. and Brakhage, Axel A. and Caffrey, Patrick and Cheng, Yi-Qiang and Clardy, Jon and Cox, Russell J. and {De Mot}, Ren{\'{e}} and Donadio, Stefano and Donia, Mohamed S. and {van der Donk}, Wilfred A. and Dorrestein, Pieter C. and Doyle, Sean and Driessen, Arnold J M. and Ehling-Schulz, Monika and Entian, Karl-Dieter and Fischbach, Michael A. and Gerwick, Lena and Gerwick, William H. and Gross, Harald and Gust, Bertolt and Hertweck, Christian and H{\"{o}}fte, Monica and Jensen, Susan E. and Ju, Jianhua and Katz, Leonard and Kaysser, Leonard and Klassen, Jonathan L. and Keller, Nancy P. and Kormanec, Jan and Kuipers, Oscar P. and Kuzuyama, Tomohisa and Kyrpides, Nikos C. and Kwon, Hyung-Jin and Lautru, Sylvie and Lavigne, Rob and Lee, Chia Y. and Linquan, Bai and Liu, Xinyu and Liu, Wen and Luzhetskyy, Andriy and Mahmud, Taifo and Mast, Yvonne and M{\'{e}}ndez, Carmen and Mets{\"{a}}-Ketel{\"{a}}, Mikko and Micklefield, Jason and Mitchell, Douglas A. and Moore, Bradley S. and Moreira, Leonilde M. and M{\"{u}}ller, Rolf and Neilan, Brett A. and Nett, Markus and Nielsen, Jens and O'Gara, Fergal and Oikawa, Hideaki and Osbourn, Anne and Osburne, Marcia S. and Ostash, Bohdan and Payne, Shelley M. and Pernodet, Jean-Luc and Petricek, Miroslav and Piel, J{\"{o}}rn and Ploux, Olivier and Raaijmakers, Jos M. and Salas, Jos{\'{e}} A. and Schmitt, Esther K. and Scott, Barry and Seipke, Ryan F. and Shen, Ben and Sherman, David H. and Sivonen, Kaarina and Smanski, Michael J. and Sosio, Margherita and Stegmann, Evi and S{\"{u}}ssmuth, Roderich D. and Tahlan, Kapil and Thomas, Christopher M. and Tang, Yi and Truman, Andrew W. and Viaud, Muriel and Walton, Jonathan D. and Walsh, Christopher T. and Weber, Tilmann and {van Wezel}, Gilles P. and Wilkinson, Barrie and Willey, Joanne M. and Wohlleben, Wolfgang and Wright, Gerard D. and Ziemert, Nadine and Zhang, Changsheng and Zotchev, Sergey B. and Breitling, Rainer and Takano, Eriko and Gl{\"{o}}ckner, Frank Oliver},
  title     = {Minimum Information about a Biosynthetic Gene cluster.},
  journal   = {Nat Chem Biol},
  year      = {2015},
  volume    = {11},
  number    = {9},
  pages     = {625--631},
  abstract  = {A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.},
  doi       = {10.1038/nchembio.1890},
  keywords  = {gene clusters;},
  owner     = {Sebastian},
  pmid      = {26284661},
  timestamp = {2016.03.07},
}

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