Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren: a cross-sectional study. Middelkoop, K., Walker, N., Stewart, J., Delport, C., Jolliffe, D. A, Nuttall, J., Coussens, A. K, Naude, C. E, Tang, J. C Y, Fraser, W. D, Wilkinson, R. J, Bekker, L., & Martineau, A. R Nutrients, 14:1263, Multidisciplinary Digital Publishing Institute, mar, 2022. ![Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren: a cross-sectional study [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Vitamin D deficiency (25-hydroxyvitamin D[25(OH)D] \textless50 nmol/L) is common among adults in Cape Town, South Africa, but studies investigating vitamin D status of children in this setting are lacking. We conducted a cross-sectional study to determine the prevalence and determinants of vitamin D deficiency in 1825 Cape Town schoolchildren aged 6–11 years. Prevalence of vitamin D deficiency was 7.6% (95% Confidence Interval [CI] 6.5% to 8.9%). Determinants of vitamin D deficiency included month of sampling (adjusted odds ratio [aOR] for July–September vs. January–March 10.69, 95% CI 5.02 to 22.77; aOR for October–December vs. January–March 6.73, 95% CI 2.82 to 16.08), older age (aOR 1.25 per increasing year, 95% CI: 1.01–1.53) and higher body mass index (BMI; aOR 1.24 per unit increase in BMI-for-age Z-score, 95% CI: 1.03–1.49). In a subset of 370 participants in whom parathyroid hormone (PTH) concentrations were measured; these were inversely related to serum 25(OH)D concentrations (p \textless 0.001). However, no association between participants with hyperparathyroidism (PTH \textgreater6.9 pmol/L) and vitamin D deficiency was seen (p = 0.42). In conclusion, we report that season is the major determinant of vitamin D status among Cape Town primary schoolchildren, with prevalence of vitamin D deficiency ranging from 1.4% in January–March to 22.8% in July–September.
@article{Middelkoop2022,
abstract = {Vitamin D deficiency (25-hydroxyvitamin D[25(OH)D] {\textless}50 nmol/L) is common among adults in Cape Town, South Africa, but studies investigating vitamin D status of children in this setting are lacking. We conducted a cross-sectional study to determine the prevalence and determinants of vitamin D deficiency in 1825 Cape Town schoolchildren aged 6–11 years. Prevalence of vitamin D deficiency was 7.6{\%} (95{\%} Confidence Interval [CI] 6.5{\%} to 8.9{\%}). Determinants of vitamin D deficiency included month of sampling (adjusted odds ratio [aOR] for July–September vs. January–March 10.69, 95{\%} CI 5.02 to 22.77; aOR for October–December vs. January–March 6.73, 95{\%} CI 2.82 to 16.08), older age (aOR 1.25 per increasing year, 95{\%} CI: 1.01–1.53) and higher body mass index (BMI; aOR 1.24 per unit increase in BMI-for-age Z-score, 95{\%} CI: 1.03–1.49). In a subset of 370 participants in whom parathyroid hormone (PTH) concentrations were measured; these were inversely related to serum 25(OH)D concentrations (p {\textless} 0.001). However, no association between participants with hyperparathyroidism (PTH {\textgreater}6.9 pmol/L) and vitamin D deficiency was seen (p = 0.42). In conclusion, we report that season is the major determinant of vitamin D status among Cape Town primary schoolchildren, with prevalence of vitamin D deficiency ranging from 1.4{\%} in January–March to 22.8{\%} in July–September.},
author = {Middelkoop, Keren and Walker, Neil and Stewart, Justine and Delport, Carmen and Jolliffe, David A and Nuttall, James and Coussens, Anna K and Naude, Celeste E and Tang, Jonathan C Y and Fraser, William D and Wilkinson, Robert J and Bekker, Linda-Gail and Martineau, Adrian R},
doi = {10.3390/NU14061263},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Middelkoop et al. - 2022 - Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren a cross-sectiona.pdf:pdf},
issn = {2072-6643},
journal = {Nutrients},
keywords = {OA,South Africa,children,cross,fund{\_}ack,original,prevalence,sectional,vitamin D},
mendeley-tags = {OA,fund{\_}ack,original},
month = {mar},
pages = {1263},
pmid = {35334921},
publisher = {Multidisciplinary Digital Publishing Institute},
title = {{Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren: a cross-sectional study}},
url = {https://www.mdpi.com/2072-6643/14/6/1263/htm https://www.mdpi.com/2072-6643/14/6/1263},
volume = {14},
year = {2022}
}
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Determinants of vitamin D deficiency included month of sampling (adjusted odds ratio [aOR] for July–September vs. January–March 10.69, 95% CI 5.02 to 22.77; aOR for October–December vs. January–March 6.73, 95% CI 2.82 to 16.08), older age (aOR 1.25 per increasing year, 95% CI: 1.01–1.53) and higher body mass index (BMI; aOR 1.24 per unit increase in BMI-for-age Z-score, 95% CI: 1.03–1.49). In a subset of 370 participants in whom parathyroid hormone (PTH) concentrations were measured; these were inversely related to serum 25(OH)D concentrations (p \\textless 0.001). However, no association between participants with hyperparathyroidism (PTH \\textgreater6.9 pmol/L) and vitamin D deficiency was seen (p = 0.42). In conclusion, we report that season is the major determinant of vitamin D status among Cape Town primary schoolchildren, with prevalence of vitamin D deficiency ranging from 1.4% in January–March to 22.8% in July–September.","author":[{"propositions":[],"lastnames":["Middelkoop"],"firstnames":["Keren"],"suffixes":[]},{"propositions":[],"lastnames":["Walker"],"firstnames":["Neil"],"suffixes":[]},{"propositions":[],"lastnames":["Stewart"],"firstnames":["Justine"],"suffixes":[]},{"propositions":[],"lastnames":["Delport"],"firstnames":["Carmen"],"suffixes":[]},{"propositions":[],"lastnames":["Jolliffe"],"firstnames":["David","A"],"suffixes":[]},{"propositions":[],"lastnames":["Nuttall"],"firstnames":["James"],"suffixes":[]},{"propositions":[],"lastnames":["Coussens"],"firstnames":["Anna","K"],"suffixes":[]},{"propositions":[],"lastnames":["Naude"],"firstnames":["Celeste","E"],"suffixes":[]},{"propositions":[],"lastnames":["Tang"],"firstnames":["Jonathan","C","Y"],"suffixes":[]},{"propositions":[],"lastnames":["Fraser"],"firstnames":["William","D"],"suffixes":[]},{"propositions":[],"lastnames":["Wilkinson"],"firstnames":["Robert","J"],"suffixes":[]},{"propositions":[],"lastnames":["Bekker"],"firstnames":["Linda-Gail"],"suffixes":[]},{"propositions":[],"lastnames":["Martineau"],"firstnames":["Adrian","R"],"suffixes":[]}],"doi":"10.3390/NU14061263","file":":C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Middelkoop et al. - 2022 - Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren a cross-sectiona.pdf:pdf","issn":"2072-6643","journal":"Nutrients","keywords":"OA,South Africa,children,cross,fund_ack,original,prevalence,sectional,vitamin D","mendeley-tags":"OA,fund_ack,original","month":"mar","pages":"1263","pmid":"35334921","publisher":"Multidisciplinary Digital Publishing Institute","title":"Prevalence and determinants of vitamin D deficiency in 1825 Cape Town primary schoolchildren: a cross-sectional study","url":"https://www.mdpi.com/2072-6643/14/6/1263/htm https://www.mdpi.com/2072-6643/14/6/1263","volume":"14","year":"2022","bibtex":"@article{Middelkoop2022,\r\nabstract = {Vitamin D deficiency (25-hydroxyvitamin D[25(OH)D] {\\textless}50 nmol/L) is common among adults in Cape Town, South Africa, but studies investigating vitamin D status of children in this setting are lacking. 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