@article{miethkes41570021003131,
    author = {Miethke, Marcus and Pieroni, Marco and Weber, Tilmann and Brönstrup, Mark and Hammann, Peter and Halby, Ludovic and Arimondo, Paola and Glaser, Philippe and Aigle, Bertrand and Bode, Helge and Moreira, Rui and Li, Yanyan and Luzhetskyy, Andriy and Medema, Marnix and Pernodet, Jean-Luc and Stadler, Marc and Tormo, Jose and Genilloud, Olga and Truman, Andrew and Weissman, Kira J. and Takano, Eriko and Sabatini, Stefano and Stegmann, Evi and Brötz-Oesterhelt, Heike and Wohlleben, Wolfgang and Seemann, Myriam and Empting, Martin and Hirsch, Anna K. H. and Loretz, Brigitta and Lehr, Claus-Michael and Titz, Alexander and Herrmann, Jennifer and Jaeger, Timo and Alt, Silke and Hesterkamp, Thomas and Winterhalter, Mathias and Schiefer, Andrea and Pfarr, Kenneth and Hoerauf, Achim and Graz, Heather and Graz, Michael and Lindvall, Mika and Ramurthy, Savithri and Karlén, Anders and Dongen, Maarten van and Petkovic, Hrvoje and Keller, Andreas and Peyrane, Frédéric and Donadio, Stefano and Fraisse, Laurent and Piddock, Laura J. V. and Gilbert, Ian H. and Moser, Heinz E. and Müller, Rolf},
    year = {2021},
    month = {08},
    pages = {1-24},
    abstract = {An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to the current level of investment in their development, particularly in the fields of natural-product-derived and synthetic small molecules. New agents displaying innovative chemistry and modes of action are desperately needed worldwide to tackle the public health menace posed by antimicrobial resistance. Here, our consortium presents a strategic blueprint to substantially improve our ability to discover and develop new antibiotics. We propose both short-term and long-term solutions to overcome the most urgent limitations in the various sectors of research and funding, aiming to bridge the gap between academic, industrial and political stakeholders, and to unite interdisciplinary expertise in order to efficiently fuel the translational pipeline for the benefit of future generations.},
    title = {Towards the sustainable discovery and development of new antibiotics},
    journal = {Nature Reviews Chemistry},
    doi = {10.1038/s41570-021-00313-1}
}

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New agents displaying innovative chemistry and modes of action are desperately needed worldwide to tackle the public health menace posed by antimicrobial resistance. Here, our consortium presents a strategic blueprint to substantially improve our ability to discover and develop new antibiotics. We propose both short-term and long-term solutions to overcome the most urgent limitations in the various sectors of research and funding, aiming to bridge the gap between academic, industrial and political stakeholders, and to unite interdisciplinary expertise in order to efficiently fuel the translational pipeline for the benefit of future generations.","title":"Towards the sustainable discovery and development of new antibiotics","journal":"Nature Reviews Chemistry","doi":"10.1038/s41570-021-00313-1","bibtex":"@article{miethkes41570021003131,\n author = {Miethke, Marcus and Pieroni, Marco and Weber, Tilmann and Brönstrup, Mark and Hammann, Peter and Halby, Ludovic and Arimondo, Paola and Glaser, Philippe and Aigle, Bertrand and Bode, Helge and Moreira, Rui and Li, Yanyan and Luzhetskyy, Andriy and Medema, Marnix and Pernodet, Jean-Luc and Stadler, Marc and Tormo, Jose and Genilloud, Olga and Truman, Andrew and Weissman, Kira J. and Takano, Eriko and Sabatini, Stefano and Stegmann, Evi and Brötz-Oesterhelt, Heike and Wohlleben, Wolfgang and Seemann, Myriam and Empting, Martin and Hirsch, Anna K. H. and Loretz, Brigitta and Lehr, Claus-Michael and Titz, Alexander and Herrmann, Jennifer and Jaeger, Timo and Alt, Silke and Hesterkamp, Thomas and Winterhalter, Mathias and Schiefer, Andrea and Pfarr, Kenneth and Hoerauf, Achim and Graz, Heather and Graz, Michael and Lindvall, Mika and Ramurthy, Savithri and Karlén, Anders and Dongen, Maarten van and Petkovic, Hrvoje and Keller, Andreas and Peyrane, Frédéric and Donadio, Stefano and Fraisse, Laurent and Piddock, Laura J. V. and Gilbert, Ian H. and Moser, Heinz E. and Müller, Rolf},\n year = {2021},\n month = {08},\n pages = {1-24},\n abstract = {An ever-increasing demand for novel antimicrobials to treat life-threatening infections caused by the global spread of multidrug-resistant bacterial pathogens stands in stark contrast to the current level of investment in their development, particularly in the fields of natural-product-derived and synthetic small molecules. New agents displaying innovative chemistry and modes of action are desperately needed worldwide to tackle the public health menace posed by antimicrobial resistance. Here, our consortium presents a strategic blueprint to substantially improve our ability to discover and develop new antibiotics. We propose both short-term and long-term solutions to overcome the most urgent limitations in the various sectors of research and funding, aiming to bridge the gap between academic, industrial and political stakeholders, and to unite interdisciplinary expertise in order to efficiently fuel the translational pipeline for the benefit of future generations.},\n title = {Towards the sustainable discovery and development of new antibiotics},\n journal = {Nature Reviews Chemistry},\n doi = {10.1038/s41570-021-00313-1}\n}\n","author_short":["Miethke, M.","Pieroni, M.","Weber, T.","Brönstrup, M.","Hammann, P.","Halby, L.","Arimondo, P.","Glaser, P.","Aigle, B.","Bode, H.","Moreira, R.","Li, Y.","Luzhetskyy, A.","Medema, M.","Pernodet, J.","Stadler, M.","Tormo, J.","Genilloud, O.","Truman, A.","Weissman, K. J.","Takano, E.","Sabatini, S.","Stegmann, E.","Brötz-Oesterhelt, H.","Wohlleben, W.","Seemann, M.","Empting, M.","Hirsch, A. K. 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