@article{Mitrani2021,
abstract = {OBJECTIVE: To describe the medical, socio-economic and geographical profiles of patients with rifampicin-resistant TB (RR-TB) and the implications for the provision of patient-centred care. SETTING: Thirteen districts across three South African provinces. DESIGN: This descriptive study examined laboratory and healthcare facility records of 194 patients diagnosed with RR-TB in the third quarter of 2016. RESULTS: The median age was 35 years; 120/194 (62{\%}) of patients were male. Previous TB treatment was documented in 122/194 (63{\%}) patients and 56/194 (29{\%}) had a record of fluoroquinolone and/or second-line injectable resistance. Of 134 (69{\%}) HIV-positive patients, viral loads were available for 68/134 (51{\%}) (36/68 [53{\%}] had viral loads of {\textgreater}1000 copies/ml) and CD4 counts were available for 92/134 (69{\%}) (20/92 [22{\%}] had CD4 {\textless}50 cells/mm 3 ). Patients presented with varying other comorbidities, including hypertension (13/194, 7{\%}) and mental health conditions (11/194, 6{\%}). Of 194 patients, 44 (23{\%}) were reported to be employed. Other socio-economic challenges included substance abuse (17/194, 9{\%}) and ill family members (17/194, 9{\%}). Respectively 13{\%} and 42{\%} of patients were estimated to travel more than 20 km to reach their diagnosing and treatment-initiating healthcare facility. CONCLUSIONS: RR-TB patients had diverse medical and social challenges highlighting the need for integrated, differentiated and patient-centred healthcare to better address specific needs and underlying vulnerabilities of individual patients.},
author = {Mitrani, L and Dickson-Hall, L and {Le Roux}, S and Hill, J and Loveday, M and Grant, A D and Kielmann, K and Mlisana, K and Moshabela, M and Nicol, M P and Black, J and Cox, Helen},
doi = {10.5588/PHA.20.0083},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Mitrani et al. - 2021 - Diverse clinical and social circumstances developing patient-centred care for DR-TB patients in South Africa.pdf:pdf},
journal = {Public Health Action},
keywords = {OA,OA{\_}PMC,fund{\_}not{\_}ack,original},
mendeley-tags = {OA,OA{\_}PMC,fund{\_}not{\_}ack,original},
month = {sep},
number = {3},
pages = {120--125},
pmid = {34567987},
publisher = {The International Union Against Tuberculosis and Lung Disease},
title = {{Diverse clinical and social circumstances: developing patient-centred care for DR-TB patients in South Africa}},
url = {/pmc/articles/PMC8455019/ /pmc/articles/PMC8455019/?report=abstract https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455019/},
volume = {11},
year = {2021}
}

{"_id":"FycXYZRuAi34wgpJp","bibbaseid":"mitrani-dicksonhall-leroux-hill-loveday-grant-kielmann-mlisana-etal-diverseclinicalandsocialcircumstancesdevelopingpatientcentredcarefordrtbpatientsinsouthafrica-2021","author_short":["Mitrani, L","Dickson-Hall, L","Le Roux, S","Hill, J","Loveday, M","Grant, A D","Kielmann, K","Mlisana, K","Moshabela, M","Nicol, M P","Black, J","Cox, H."],"bibdata":{"bibtype":"article","type":"article","abstract":"OBJECTIVE: To describe the medical, socio-economic and geographical profiles of patients with rifampicin-resistant TB (RR-TB) and the implications for the provision of patient-centred care. SETTING: Thirteen districts across three South African provinces. DESIGN: This descriptive study examined laboratory and healthcare facility records of 194 patients diagnosed with RR-TB in the third quarter of 2016. RESULTS: The median age was 35 years; 120/194 (62%) of patients were male. Previous TB treatment was documented in 122/194 (63%) patients and 56/194 (29%) had a record of fluoroquinolone and/or second-line injectable resistance. Of 134 (69%) HIV-positive patients, viral loads were available for 68/134 (51%) (36/68 [53%] had viral loads of \\textgreater1000 copies/ml) and CD4 counts were available for 92/134 (69%) (20/92 [22%] had CD4 \\textless50 cells/mm 3 ). Patients presented with varying other comorbidities, including hypertension (13/194, 7%) and mental health conditions (11/194, 6%). Of 194 patients, 44 (23%) were reported to be employed. Other socio-economic challenges included substance abuse (17/194, 9%) and ill family members (17/194, 9%). Respectively 13% and 42% of patients were estimated to travel more than 20 km to reach their diagnosing and treatment-initiating healthcare facility. CONCLUSIONS: RR-TB patients had diverse medical and social challenges highlighting the need for integrated, differentiated and patient-centred healthcare to better address specific needs and underlying vulnerabilities of individual patients.","author":[{"propositions":[],"lastnames":["Mitrani"],"firstnames":["L"],"suffixes":[]},{"propositions":[],"lastnames":["Dickson-Hall"],"firstnames":["L"],"suffixes":[]},{"propositions":[],"lastnames":["Le Roux"],"firstnames":["S"],"suffixes":[]},{"propositions":[],"lastnames":["Hill"],"firstnames":["J"],"suffixes":[]},{"propositions":[],"lastnames":["Loveday"],"firstnames":["M"],"suffixes":[]},{"propositions":[],"lastnames":["Grant"],"firstnames":["A","D"],"suffixes":[]},{"propositions":[],"lastnames":["Kielmann"],"firstnames":["K"],"suffixes":[]},{"propositions":[],"lastnames":["Mlisana"],"firstnames":["K"],"suffixes":[]},{"propositions":[],"lastnames":["Moshabela"],"firstnames":["M"],"suffixes":[]},{"propositions":[],"lastnames":["Nicol"],"firstnames":["M","P"],"suffixes":[]},{"propositions":[],"lastnames":["Black"],"firstnames":["J"],"suffixes":[]},{"propositions":[],"lastnames":["Cox"],"firstnames":["Helen"],"suffixes":[]}],"doi":"10.5588/PHA.20.0083","file":":C$\\$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Mitrani et al. - 2021 - Diverse clinical and social circumstances developing patient-centred care for DR-TB patients in South Africa.pdf:pdf","journal":"Public Health Action","keywords":"OA,OA_PMC,fund_not_ack,original","mendeley-tags":"OA,OA_PMC,fund_not_ack,original","month":"sep","number":"3","pages":"120–125","pmid":"34567987","publisher":"The International Union Against Tuberculosis and Lung Disease","title":"Diverse clinical and social circumstances: developing patient-centred care for DR-TB patients in South Africa","url":"/pmc/articles/PMC8455019/ /pmc/articles/PMC8455019/?report=abstract https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455019/","volume":"11","year":"2021","bibtex":"@article{Mitrani2021,\r\nabstract = {OBJECTIVE: To describe the medical, socio-economic and geographical profiles of patients with rifampicin-resistant TB (RR-TB) and the implications for the provision of patient-centred care. SETTING: Thirteen districts across three South African provinces. DESIGN: This descriptive study examined laboratory and healthcare facility records of 194 patients diagnosed with RR-TB in the third quarter of 2016. RESULTS: The median age was 35 years; 120/194 (62{\\%}) of patients were male. Previous TB treatment was documented in 122/194 (63{\\%}) patients and 56/194 (29{\\%}) had a record of fluoroquinolone and/or second-line injectable resistance. Of 134 (69{\\%}) HIV-positive patients, viral loads were available for 68/134 (51{\\%}) (36/68 [53{\\%}] had viral loads of {\\textgreater}1000 copies/ml) and CD4 counts were available for 92/134 (69{\\%}) (20/92 [22{\\%}] had CD4 {\\textless}50 cells/mm 3 ). Patients presented with varying other comorbidities, including hypertension (13/194, 7{\\%}) and mental health conditions (11/194, 6{\\%}). Of 194 patients, 44 (23{\\%}) were reported to be employed. Other socio-economic challenges included substance abuse (17/194, 9{\\%}) and ill family members (17/194, 9{\\%}). Respectively 13{\\%} and 42{\\%} of patients were estimated to travel more than 20 km to reach their diagnosing and treatment-initiating healthcare facility. CONCLUSIONS: RR-TB patients had diverse medical and social challenges highlighting the need for integrated, differentiated and patient-centred healthcare to better address specific needs and underlying vulnerabilities of individual patients.},\r\nauthor = {Mitrani, L and Dickson-Hall, L and {Le Roux}, S and Hill, J and Loveday, M and Grant, A D and Kielmann, K and Mlisana, K and Moshabela, M and Nicol, M P and Black, J and Cox, Helen},\r\ndoi = {10.5588/PHA.20.0083},\r\nfile = {:C$\\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Mitrani et al. - 2021 - Diverse clinical and social circumstances developing patient-centred care for DR-TB patients in South Africa.pdf:pdf},\r\njournal = {Public Health Action},\r\nkeywords = {OA,OA{\\_}PMC,fund{\\_}not{\\_}ack,original},\r\nmendeley-tags = {OA,OA{\\_}PMC,fund{\\_}not{\\_}ack,original},\r\nmonth = {sep},\r\nnumber = {3},\r\npages = {120--125},\r\npmid = {34567987},\r\npublisher = {The International Union Against Tuberculosis and Lung Disease},\r\ntitle = {{Diverse clinical and social circumstances: developing patient-centred care for DR-TB patients in South Africa}},\r\nurl = {/pmc/articles/PMC8455019/ /pmc/articles/PMC8455019/?report=abstract https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455019/},\r\nvolume = {11},\r\nyear = {2021}\r\n}\r\n","author_short":["Mitrani, L","Dickson-Hall, L","Le Roux, S","Hill, J","Loveday, M","Grant, A D","Kielmann, K","Mlisana, K","Moshabela, M","Nicol, M P","Black, J","Cox, H."],"key":"Mitrani2021","id":"Mitrani2021","bibbaseid":"mitrani-dicksonhall-leroux-hill-loveday-grant-kielmann-mlisana-etal-diverseclinicalandsocialcircumstancesdevelopingpatientcentredcarefordrtbpatientsinsouthafrica-2021","role":"author","urls":{"Paper":"https://drive.google.com/pmc/articles/PMC8455019/%20/pmc/articles/PMC8455019/?report=abstract%20https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455019/"},"keyword":["OA","OA_PMC","fund_not_ack","original"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://drive.google.com/uc?export=download&id=1-JLqZ7RwZ3VC2d6ErLGHAtOeMRS_7GCz","dataSources":["Krmt6gt9ktB2s6ARh"],"keywords":["oa","oa_pmc","fund_not_ack","original"],"search_terms":["diverse","clinical","social","circumstances","developing","patient","centred","care","patients","south","africa","mitrani","dickson-hall","le roux","hill","loveday","grant","kielmann","mlisana","moshabela","nicol","black","cox"],"title":"Diverse clinical and social circumstances: developing patient-centred care for DR-TB patients in South Africa","year":2021}