Less Social Deprivation Is Associated With Better Health-Related Quality of Life in Asthma and Is Mediated by Less Anxiety and Better Sleep Quality. Moitra, S., Adan, A., Akgün, M., Anderson, A., Brickstock, A., Eathorne, A., Farshchi Tabrizi, A., Haldar, P., Henderson, L., Jindal, A., Jindal, S. K., Kerget, B., Khadour, F., Melenka, L., Moitra, S., Moitra, T., Mukherjee, R., Semprini, A., Turner, A. M., Murgia, N., Ferrara, G., & Lacy, P. The Journal of Allergy and Clinical Immunology. In Practice, 11(7):2115–2124.e7, July, 2023. doi abstract bibtex BACKGROUND: Previous studies on health-related quality of life (HRQoL) in asthma have mainly focused on clinical and environmental determinants. Little is known about the role of social determinants on HRQoL in asthma. OBJECTIVES: We aimed to investigate the association between social deprivation and HRQoL in asthma. METHODS: A total of 691 adult asthmatics from Canada, India, New Zealand, and the United Kingdom were administered a digital questionnaire containing demographic information and questions about social and psychological attributes, sleep disturbances, and alcohol abuse. HRQoL was measured using the Short Form of the Chronic Respiratory Questionnaire (SF-CRQ). We analyzed the direct and indirect relationships between social deprivation and HRQoL using structural equation models with social deprivation as a latent variable. We tested for mediation via anxiety, depression, sleep disturbances, and alcohol abuse. RESULTS: We found that less social deprivation (latent variable) was directly associated with better SF-CRQ domain scores such as dyspnea (regression coefficient β: 0.33; 95% confidence interval [CI]: 0.07 to 0.58), fatigue (β: 0.39; 95% CI: 0.14 to 0.64), and emotional function (β: 0.37; 95% CI: 0.11 to 0.62), but with the worse mastery score (β: -0.29; 95% CI: -0.55 to -0.03); however, those associations varied across participating countries. We also observed that among all individual social deprivation indicators, education, companionship, emotional support, instrumental support, and social isolation were directly associated with HRQoL, and the relationship between social deprivation and HRQoL was mediated through anxiety and sleep disturbances. CONCLUSIONS: Our results demonstrated that less social deprivation was directly, and indirectly through less anxiety and better sleep quality, associated with better HRQoL in asthma.
@article{moitra_less_2023,
title = {Less {Social} {Deprivation} {Is} {Associated} {With} {Better} {Health}-{Related} {Quality} of {Life} in {Asthma} and {Is} {Mediated} by {Less} {Anxiety} and {Better} {Sleep} {Quality}},
volume = {11},
issn = {2213-2201},
doi = {10.1016/j.jaip.2023.03.052},
abstract = {BACKGROUND: Previous studies on health-related quality of life (HRQoL) in asthma have mainly focused on clinical and environmental determinants. Little is known about the role of social determinants on HRQoL in asthma.
OBJECTIVES: We aimed to investigate the association between social deprivation and HRQoL in asthma.
METHODS: A total of 691 adult asthmatics from Canada, India, New Zealand, and the United Kingdom were administered a digital questionnaire containing demographic information and questions about social and psychological attributes, sleep disturbances, and alcohol abuse. HRQoL was measured using the Short Form of the Chronic Respiratory Questionnaire (SF-CRQ). We analyzed the direct and indirect relationships between social deprivation and HRQoL using structural equation models with social deprivation as a latent variable. We tested for mediation via anxiety, depression, sleep disturbances, and alcohol abuse.
RESULTS: We found that less social deprivation (latent variable) was directly associated with better SF-CRQ domain scores such as dyspnea (regression coefficient β: 0.33; 95\% confidence interval [CI]: 0.07 to 0.58), fatigue (β: 0.39; 95\% CI: 0.14 to 0.64), and emotional function (β: 0.37; 95\% CI: 0.11 to 0.62), but with the worse mastery score (β: -0.29; 95\% CI: -0.55 to -0.03); however, those associations varied across participating countries. We also observed that among all individual social deprivation indicators, education, companionship, emotional support, instrumental support, and social isolation were directly associated with HRQoL, and the relationship between social deprivation and HRQoL was mediated through anxiety and sleep disturbances.
CONCLUSIONS: Our results demonstrated that less social deprivation was directly, and indirectly through less anxiety and better sleep quality, associated with better HRQoL in asthma.},
language = {eng},
number = {7},
journal = {The Journal of Allergy and Clinical Immunology. In Practice},
author = {Moitra, Subhabrata and Adan, Ana and Akgün, Metin and Anderson, Augustus and Brickstock, Amanda and Eathorne, Allie and Farshchi Tabrizi, Ali and Haldar, Prasun and Henderson, Linda and Jindal, Aditya and Jindal, Surinder Kumar and Kerget, Bugra and Khadour, Fadi and Melenka, Lyle and Moitra, Saibal and Moitra, Tanusree and Mukherjee, Rahul and Semprini, Alex and Turner, Alice M. and Murgia, Nicola and Ferrara, Giovanni and Lacy, Paige},
month = jul,
year = {2023},
pmid = {37087095},
keywords = {Adult, Alcoholism, Anxiety, Asthma, Humans, Mental health, Quality of Life, SF-CRQ, Sleep Quality, Social Deprivation, Structural equation model, Surveys and Questionnaires},
pages = {2115--2124.e7},
}
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{"_id":"bgReA6KqxymWbu8ja","bibbaseid":"moitra-adan-akgn-anderson-brickstock-eathorne-farshchitabrizi-haldar-etal-lesssocialdeprivationisassociatedwithbetterhealthrelatedqualityoflifeinasthmaandismediatedbylessanxietyandbettersleepquality-2023","author_short":["Moitra, S.","Adan, A.","Akgün, M.","Anderson, A.","Brickstock, A.","Eathorne, A.","Farshchi Tabrizi, A.","Haldar, P.","Henderson, L.","Jindal, A.","Jindal, S. K.","Kerget, B.","Khadour, F.","Melenka, L.","Moitra, S.","Moitra, T.","Mukherjee, R.","Semprini, A.","Turner, A. M.","Murgia, N.","Ferrara, G.","Lacy, P."],"bibdata":{"bibtype":"article","type":"article","title":"Less Social Deprivation Is Associated With Better Health-Related Quality of Life in Asthma and Is Mediated by Less Anxiety and Better Sleep Quality","volume":"11","issn":"2213-2201","doi":"10.1016/j.jaip.2023.03.052","abstract":"BACKGROUND: Previous studies on health-related quality of life (HRQoL) in asthma have mainly focused on clinical and environmental determinants. Little is known about the role of social determinants on HRQoL in asthma. OBJECTIVES: We aimed to investigate the association between social deprivation and HRQoL in asthma. METHODS: A total of 691 adult asthmatics from Canada, India, New Zealand, and the United Kingdom were administered a digital questionnaire containing demographic information and questions about social and psychological attributes, sleep disturbances, and alcohol abuse. HRQoL was measured using the Short Form of the Chronic Respiratory Questionnaire (SF-CRQ). We analyzed the direct and indirect relationships between social deprivation and HRQoL using structural equation models with social deprivation as a latent variable. We tested for mediation via anxiety, depression, sleep disturbances, and alcohol abuse. RESULTS: We found that less social deprivation (latent variable) was directly associated with better SF-CRQ domain scores such as dyspnea (regression coefficient β: 0.33; 95% confidence interval [CI]: 0.07 to 0.58), fatigue (β: 0.39; 95% CI: 0.14 to 0.64), and emotional function (β: 0.37; 95% CI: 0.11 to 0.62), but with the worse mastery score (β: -0.29; 95% CI: -0.55 to -0.03); however, those associations varied across participating countries. We also observed that among all individual social deprivation indicators, education, companionship, emotional support, instrumental support, and social isolation were directly associated with HRQoL, and the relationship between social deprivation and HRQoL was mediated through anxiety and sleep disturbances. CONCLUSIONS: Our results demonstrated that less social deprivation was directly, and indirectly through less anxiety and better sleep quality, associated with better HRQoL in asthma.","language":"eng","number":"7","journal":"The Journal of Allergy and Clinical Immunology. In Practice","author":[{"propositions":[],"lastnames":["Moitra"],"firstnames":["Subhabrata"],"suffixes":[]},{"propositions":[],"lastnames":["Adan"],"firstnames":["Ana"],"suffixes":[]},{"propositions":[],"lastnames":["Akgün"],"firstnames":["Metin"],"suffixes":[]},{"propositions":[],"lastnames":["Anderson"],"firstnames":["Augustus"],"suffixes":[]},{"propositions":[],"lastnames":["Brickstock"],"firstnames":["Amanda"],"suffixes":[]},{"propositions":[],"lastnames":["Eathorne"],"firstnames":["Allie"],"suffixes":[]},{"propositions":[],"lastnames":["Farshchi","Tabrizi"],"firstnames":["Ali"],"suffixes":[]},{"propositions":[],"lastnames":["Haldar"],"firstnames":["Prasun"],"suffixes":[]},{"propositions":[],"lastnames":["Henderson"],"firstnames":["Linda"],"suffixes":[]},{"propositions":[],"lastnames":["Jindal"],"firstnames":["Aditya"],"suffixes":[]},{"propositions":[],"lastnames":["Jindal"],"firstnames":["Surinder","Kumar"],"suffixes":[]},{"propositions":[],"lastnames":["Kerget"],"firstnames":["Bugra"],"suffixes":[]},{"propositions":[],"lastnames":["Khadour"],"firstnames":["Fadi"],"suffixes":[]},{"propositions":[],"lastnames":["Melenka"],"firstnames":["Lyle"],"suffixes":[]},{"propositions":[],"lastnames":["Moitra"],"firstnames":["Saibal"],"suffixes":[]},{"propositions":[],"lastnames":["Moitra"],"firstnames":["Tanusree"],"suffixes":[]},{"propositions":[],"lastnames":["Mukherjee"],"firstnames":["Rahul"],"suffixes":[]},{"propositions":[],"lastnames":["Semprini"],"firstnames":["Alex"],"suffixes":[]},{"propositions":[],"lastnames":["Turner"],"firstnames":["Alice","M."],"suffixes":[]},{"propositions":[],"lastnames":["Murgia"],"firstnames":["Nicola"],"suffixes":[]},{"propositions":[],"lastnames":["Ferrara"],"firstnames":["Giovanni"],"suffixes":[]},{"propositions":[],"lastnames":["Lacy"],"firstnames":["Paige"],"suffixes":[]}],"month":"July","year":"2023","pmid":"37087095","keywords":"Adult, Alcoholism, Anxiety, Asthma, Humans, Mental health, Quality of Life, SF-CRQ, Sleep Quality, Social Deprivation, Structural equation model, Surveys and Questionnaires","pages":"2115–2124.e7","bibtex":"@article{moitra_less_2023,\n\ttitle = {Less {Social} {Deprivation} {Is} {Associated} {With} {Better} {Health}-{Related} {Quality} of {Life} in {Asthma} and {Is} {Mediated} by {Less} {Anxiety} and {Better} {Sleep} {Quality}},\n\tvolume = {11},\n\tissn = {2213-2201},\n\tdoi = {10.1016/j.jaip.2023.03.052},\n\tabstract = {BACKGROUND: Previous studies on health-related quality of life (HRQoL) in asthma have mainly focused on clinical and environmental determinants. Little is known about the role of social determinants on HRQoL in asthma.\nOBJECTIVES: We aimed to investigate the association between social deprivation and HRQoL in asthma.\nMETHODS: A total of 691 adult asthmatics from Canada, India, New Zealand, and the United Kingdom were administered a digital questionnaire containing demographic information and questions about social and psychological attributes, sleep disturbances, and alcohol abuse. HRQoL was measured using the Short Form of the Chronic Respiratory Questionnaire (SF-CRQ). We analyzed the direct and indirect relationships between social deprivation and HRQoL using structural equation models with social deprivation as a latent variable. We tested for mediation via anxiety, depression, sleep disturbances, and alcohol abuse.\nRESULTS: We found that less social deprivation (latent variable) was directly associated with better SF-CRQ domain scores such as dyspnea (regression coefficient β: 0.33; 95\\% confidence interval [CI]: 0.07 to 0.58), fatigue (β: 0.39; 95\\% CI: 0.14 to 0.64), and emotional function (β: 0.37; 95\\% CI: 0.11 to 0.62), but with the worse mastery score (β: -0.29; 95\\% CI: -0.55 to -0.03); however, those associations varied across participating countries. We also observed that among all individual social deprivation indicators, education, companionship, emotional support, instrumental support, and social isolation were directly associated with HRQoL, and the relationship between social deprivation and HRQoL was mediated through anxiety and sleep disturbances.\nCONCLUSIONS: Our results demonstrated that less social deprivation was directly, and indirectly through less anxiety and better sleep quality, associated with better HRQoL in asthma.},\n\tlanguage = {eng},\n\tnumber = {7},\n\tjournal = {The Journal of Allergy and Clinical Immunology. In Practice},\n\tauthor = {Moitra, Subhabrata and Adan, Ana and Akgün, Metin and Anderson, Augustus and Brickstock, Amanda and Eathorne, Allie and Farshchi Tabrizi, Ali and Haldar, Prasun and Henderson, Linda and Jindal, Aditya and Jindal, Surinder Kumar and Kerget, Bugra and Khadour, Fadi and Melenka, Lyle and Moitra, Saibal and Moitra, Tanusree and Mukherjee, Rahul and Semprini, Alex and Turner, Alice M. and Murgia, Nicola and Ferrara, Giovanni and Lacy, Paige},\n\tmonth = jul,\n\tyear = {2023},\n\tpmid = {37087095},\n\tkeywords = {Adult, Alcoholism, Anxiety, Asthma, Humans, Mental health, Quality of Life, SF-CRQ, Sleep Quality, Social Deprivation, Structural equation model, Surveys and Questionnaires},\n\tpages = {2115--2124.e7},\n}\n\n","author_short":["Moitra, S.","Adan, A.","Akgün, M.","Anderson, A.","Brickstock, A.","Eathorne, A.","Farshchi Tabrizi, A.","Haldar, P.","Henderson, L.","Jindal, A.","Jindal, S. K.","Kerget, B.","Khadour, F.","Melenka, L.","Moitra, S.","Moitra, T.","Mukherjee, R.","Semprini, A.","Turner, A. 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