Characteristics and outcomes of COVID-19 patients with COPD from the United States, South Korea, and Europe. Moreno-Martos, D., Verhamme, K., Ostropolets, A., Kostka, K., Duarte-Sales, T., Prieto-Alhambra, D., Alshammari, T. M., Alghoul, H., Ahmed, W. U., Blacketer, C., DuVall, S., Lai, L., Matheny, M., Nyberg, F., Posada, J., Rijnbeek, P., Spotnitz, M., Sena, A., Shah, N., Suchard, M., Chan You, S., Hripcsak, G., Ryan, P., & Morales, D. Wellcome Open Res, 7:22, 2022. 2398-502x Moreno-Martos, David Orcid: 0000-0002-8652-6235 Verhamme, Katia Ostropolets, Anna Orcid: 0000-0002-0847-6682 Kostka, Kristin Duarte-Sales, Talita Prieto-Alhambra, Daniel Alshammari, Thamir M Alghoul, Heba Orcid: 0000-0001-8234-5843 Ahmed, Waheed-Ul-Rahman Blacketer, Clair DuVall, Scott Lai, Lana Matheny, Michael Nyberg, Fredrik Orcid: 0000-0003-0892-5668 Posada, Jose Orcid: 0000-0003-3864-0241 Rijnbeek, Peter Spotnitz, Matthew Orcid: 0000-0003-2869-0237 Sena, Anthony Shah, Nigam Suchard, Marc Orcid: 0000-0001-9818-479x Chan You, Seng Orcid: 0000-0002-5052-6399 Hripcsak, George Ryan, Patrick Morales, Daniel Orcid: 0000-0002-0063-8069 Journal Article England 2023/03/01 Wellcome Open Res. 2022 Mar 24;7:22. doi: 10.12688/wellcomeopenres.17403.2. eCollection 2022.abstract bibtex Background: Characterization studies of COVID-19 patients with chronic obstructive pulmonary disease (COPD) are limited in size and scope. The aim of the study is to provide a large-scale characterization of COVID-19 patients with COPD. Methods: We included thirteen databases contributing data from January-June 2020 from North America (US), Europe and Asia. We defined two cohorts of patients with COVID-19 namely a 'diagnosed' and 'hospitalized' cohort. We followed patients from COVID-19 index date to 30 days or death. We performed descriptive analysis and reported the frequency of characteristics and outcomes among COPD patients with COVID-19. Results: The study included 934,778 patients in the diagnosed COVID-19 cohort and 177,201 in the hospitalized COVID-19 cohort. Observed COPD prevalence in the diagnosed cohort ranged from 3.8% (95%CI 3.5-4.1%) in French data to 22.7% (95%CI 22.4-23.0) in US data, and from 1.9% (95%CI 1.6-2.2) in South Korean to 44.0% (95%CI 43.1-45.0) in US data, in the hospitalized cohorts. COPD patients in the hospitalized cohort had greater comorbidity than those in the diagnosed cohort, including hypertension, heart disease, diabetes and obesity. Mortality was higher in COPD patients in the hospitalized cohort and ranged from 7.6% (95%CI 6.9-8.4) to 32.2% (95%CI 28.0-36.7) across databases. ARDS, acute renal failure, cardiac arrhythmia and sepsis were the most common outcomes among hospitalized COPD patients. Conclusion: COPD patients with COVID-19 have high levels of COVID-19-associated comorbidities and poor COVID-19 outcomes. Further research is required to identify patients with COPD at high risk of worse outcomes.
@article{RN370,
author = {Moreno-Martos, D. and Verhamme, K. and Ostropolets, A. and Kostka, K. and Duarte-Sales, T. and Prieto-Alhambra, D. and Alshammari, T. M. and Alghoul, H. and Ahmed, W. U. and Blacketer, C. and DuVall, S. and Lai, L. and Matheny, M. and Nyberg, F. and Posada, J. and Rijnbeek, P. and Spotnitz, M. and Sena, A. and Shah, N. and Suchard, M. and Chan You, S. and Hripcsak, G. and Ryan, P. and Morales, D.},
title = {Characteristics and outcomes of COVID-19 patients with COPD from the United States, South Korea, and Europe},
journal = {Wellcome Open Res},
volume = {7},
pages = {22},
note = {2398-502x Moreno-Martos, David Orcid: 0000-0002-8652-6235 Verhamme, Katia Ostropolets, Anna Orcid: 0000-0002-0847-6682 Kostka, Kristin Duarte-Sales, Talita Prieto-Alhambra, Daniel Alshammari, Thamir M Alghoul, Heba Orcid: 0000-0001-8234-5843 Ahmed, Waheed-Ul-Rahman Blacketer, Clair DuVall, Scott Lai, Lana Matheny, Michael Nyberg, Fredrik Orcid: 0000-0003-0892-5668 Posada, Jose Orcid: 0000-0003-3864-0241 Rijnbeek, Peter Spotnitz, Matthew Orcid: 0000-0003-2869-0237 Sena, Anthony Shah, Nigam Suchard, Marc Orcid: 0000-0001-9818-479x Chan You, Seng Orcid: 0000-0002-5052-6399 Hripcsak, George Ryan, Patrick Morales, Daniel Orcid: 0000-0002-0063-8069 Journal Article England 2023/03/01 Wellcome Open Res. 2022 Mar 24;7:22. doi: 10.12688/wellcomeopenres.17403.2. eCollection 2022.},
abstract = {Background: Characterization studies of COVID-19 patients with chronic obstructive pulmonary disease (COPD) are limited in size and scope. The aim of the study is to provide a large-scale characterization of COVID-19 patients with COPD. Methods: We included thirteen databases contributing data from January-June 2020 from North America (US), Europe and Asia. We defined two cohorts of patients with COVID-19 namely a 'diagnosed' and 'hospitalized' cohort. We followed patients from COVID-19 index date to 30 days or death. We performed descriptive analysis and reported the frequency of characteristics and outcomes among COPD patients with COVID-19. Results: The study included 934,778 patients in the diagnosed COVID-19 cohort and 177,201 in the hospitalized COVID-19 cohort. Observed COPD prevalence in the diagnosed cohort ranged from 3.8% (95%CI 3.5-4.1%) in French data to 22.7% (95%CI 22.4-23.0) in US data, and from 1.9% (95%CI 1.6-2.2) in South Korean to 44.0% (95%CI 43.1-45.0) in US data, in the hospitalized cohorts. COPD patients in the hospitalized cohort had greater comorbidity than those in the diagnosed cohort, including hypertension, heart disease, diabetes and obesity. Mortality was higher in COPD patients in the hospitalized cohort and ranged from 7.6% (95%CI 6.9-8.4) to 32.2% (95%CI 28.0-36.7) across databases. ARDS, acute renal failure, cardiac arrhythmia and sepsis were the most common outcomes among hospitalized COPD patients. Conclusion: COPD patients with COVID-19 have high levels of COVID-19-associated comorbidities and poor COVID-19 outcomes. Further research is required to identify patients with COPD at high risk of worse outcomes.},
keywords = {Copd
Covid
SARS-CoV-2
coronavirus
epidemiology. ,
ISSN = 2398-502X (Print) 2398-502x ,
DOI = 10.12688/wellcomeopenres.17403.2},
year = {2022},
type = {Journal Article}
}
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{"_id":"sAq65bspcbfPwi44L","bibbaseid":"morenomartos-verhamme-ostropolets-kostka-duartesales-prietoalhambra-alshammari-alghoul-etal-characteristicsandoutcomesofcovid19patientswithcopdfromtheunitedstatessouthkoreaandeurope-2022","author_short":["Moreno-Martos, D.","Verhamme, K.","Ostropolets, A.","Kostka, K.","Duarte-Sales, T.","Prieto-Alhambra, D.","Alshammari, T. M.","Alghoul, H.","Ahmed, W. U.","Blacketer, C.","DuVall, S.","Lai, L.","Matheny, M.","Nyberg, F.","Posada, J.","Rijnbeek, P.","Spotnitz, M.","Sena, A.","Shah, N.","Suchard, M.","Chan You, S.","Hripcsak, G.","Ryan, P.","Morales, D."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Moreno-Martos"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Verhamme"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Ostropolets"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Kostka"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Duarte-Sales"],"firstnames":["T."],"suffixes":[]},{"propositions":[],"lastnames":["Prieto-Alhambra"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Alshammari"],"firstnames":["T.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Alghoul"],"firstnames":["H."],"suffixes":[]},{"propositions":[],"lastnames":["Ahmed"],"firstnames":["W.","U."],"suffixes":[]},{"propositions":[],"lastnames":["Blacketer"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["DuVall"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Lai"],"firstnames":["L."],"suffixes":[]},{"propositions":[],"lastnames":["Matheny"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Nyberg"],"firstnames":["F."],"suffixes":[]},{"propositions":[],"lastnames":["Posada"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Rijnbeek"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Spotnitz"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Sena"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Shah"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["Suchard"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Chan","You"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Hripcsak"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Ryan"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Morales"],"firstnames":["D."],"suffixes":[]}],"title":"Characteristics and outcomes of COVID-19 patients with COPD from the United States, South Korea, and Europe","journal":"Wellcome Open Res","volume":"7","pages":"22","note":"2398-502x Moreno-Martos, David Orcid: 0000-0002-8652-6235 Verhamme, Katia Ostropolets, Anna Orcid: 0000-0002-0847-6682 Kostka, Kristin Duarte-Sales, Talita Prieto-Alhambra, Daniel Alshammari, Thamir M Alghoul, Heba Orcid: 0000-0001-8234-5843 Ahmed, Waheed-Ul-Rahman Blacketer, Clair DuVall, Scott Lai, Lana Matheny, Michael Nyberg, Fredrik Orcid: 0000-0003-0892-5668 Posada, Jose Orcid: 0000-0003-3864-0241 Rijnbeek, Peter Spotnitz, Matthew Orcid: 0000-0003-2869-0237 Sena, Anthony Shah, Nigam Suchard, Marc Orcid: 0000-0001-9818-479x Chan You, Seng Orcid: 0000-0002-5052-6399 Hripcsak, George Ryan, Patrick Morales, Daniel Orcid: 0000-0002-0063-8069 Journal Article England 2023/03/01 Wellcome Open Res. 2022 Mar 24;7:22. doi: 10.12688/wellcomeopenres.17403.2. eCollection 2022.","abstract":"Background: Characterization studies of COVID-19 patients with chronic obstructive pulmonary disease (COPD) are limited in size and scope. The aim of the study is to provide a large-scale characterization of COVID-19 patients with COPD. Methods: We included thirteen databases contributing data from January-June 2020 from North America (US), Europe and Asia. We defined two cohorts of patients with COVID-19 namely a 'diagnosed' and 'hospitalized' cohort. We followed patients from COVID-19 index date to 30 days or death. We performed descriptive analysis and reported the frequency of characteristics and outcomes among COPD patients with COVID-19. Results: The study included 934,778 patients in the diagnosed COVID-19 cohort and 177,201 in the hospitalized COVID-19 cohort. Observed COPD prevalence in the diagnosed cohort ranged from 3.8% (95%CI 3.5-4.1%) in French data to 22.7% (95%CI 22.4-23.0) in US data, and from 1.9% (95%CI 1.6-2.2) in South Korean to 44.0% (95%CI 43.1-45.0) in US data, in the hospitalized cohorts. COPD patients in the hospitalized cohort had greater comorbidity than those in the diagnosed cohort, including hypertension, heart disease, diabetes and obesity. Mortality was higher in COPD patients in the hospitalized cohort and ranged from 7.6% (95%CI 6.9-8.4) to 32.2% (95%CI 28.0-36.7) across databases. ARDS, acute renal failure, cardiac arrhythmia and sepsis were the most common outcomes among hospitalized COPD patients. Conclusion: COPD patients with COVID-19 have high levels of COVID-19-associated comorbidities and poor COVID-19 outcomes. Further research is required to identify patients with COPD at high risk of worse outcomes.","keywords":"Copd Covid SARS-CoV-2 coronavirus epidemiology. , ISSN = 2398-502X (Print) 2398-502x , DOI = 10.12688/wellcomeopenres.17403.2","year":"2022","bibtex":"@article{RN370,\r\n author = {Moreno-Martos, D. and Verhamme, K. and Ostropolets, A. and Kostka, K. and Duarte-Sales, T. and Prieto-Alhambra, D. and Alshammari, T. M. and Alghoul, H. and Ahmed, W. U. and Blacketer, C. and DuVall, S. and Lai, L. and Matheny, M. and Nyberg, F. and Posada, J. and Rijnbeek, P. and Spotnitz, M. and Sena, A. and Shah, N. and Suchard, M. and Chan You, S. and Hripcsak, G. and Ryan, P. and Morales, D.},\r\n title = {Characteristics and outcomes of COVID-19 patients with COPD from the United States, South Korea, and Europe},\r\n journal = {Wellcome Open Res},\r\n volume = {7},\r\n pages = {22},\r\n note = {2398-502x Moreno-Martos, David Orcid: 0000-0002-8652-6235 Verhamme, Katia Ostropolets, Anna Orcid: 0000-0002-0847-6682 Kostka, Kristin Duarte-Sales, Talita Prieto-Alhambra, Daniel Alshammari, Thamir M Alghoul, Heba Orcid: 0000-0001-8234-5843 Ahmed, Waheed-Ul-Rahman Blacketer, Clair DuVall, Scott Lai, Lana Matheny, Michael Nyberg, Fredrik Orcid: 0000-0003-0892-5668 Posada, Jose Orcid: 0000-0003-3864-0241 Rijnbeek, Peter Spotnitz, Matthew Orcid: 0000-0003-2869-0237 Sena, Anthony Shah, Nigam Suchard, Marc Orcid: 0000-0001-9818-479x Chan You, Seng Orcid: 0000-0002-5052-6399 Hripcsak, George Ryan, Patrick Morales, Daniel Orcid: 0000-0002-0063-8069 Journal Article England 2023/03/01 Wellcome Open Res. 2022 Mar 24;7:22. doi: 10.12688/wellcomeopenres.17403.2. eCollection 2022.},\r\n abstract = {Background: Characterization studies of COVID-19 patients with chronic obstructive pulmonary disease (COPD) are limited in size and scope. The aim of the study is to provide a large-scale characterization of COVID-19 patients with COPD. Methods: We included thirteen databases contributing data from January-June 2020 from North America (US), Europe and Asia. We defined two cohorts of patients with COVID-19 namely a 'diagnosed' and 'hospitalized' cohort. We followed patients from COVID-19 index date to 30 days or death. We performed descriptive analysis and reported the frequency of characteristics and outcomes among COPD patients with COVID-19. Results: The study included 934,778 patients in the diagnosed COVID-19 cohort and 177,201 in the hospitalized COVID-19 cohort. Observed COPD prevalence in the diagnosed cohort ranged from 3.8% (95%CI 3.5-4.1%) in French data to 22.7% (95%CI 22.4-23.0) in US data, and from 1.9% (95%CI 1.6-2.2) in South Korean to 44.0% (95%CI 43.1-45.0) in US data, in the hospitalized cohorts. COPD patients in the hospitalized cohort had greater comorbidity than those in the diagnosed cohort, including hypertension, heart disease, diabetes and obesity. Mortality was higher in COPD patients in the hospitalized cohort and ranged from 7.6% (95%CI 6.9-8.4) to 32.2% (95%CI 28.0-36.7) across databases. ARDS, acute renal failure, cardiac arrhythmia and sepsis were the most common outcomes among hospitalized COPD patients. Conclusion: COPD patients with COVID-19 have high levels of COVID-19-associated comorbidities and poor COVID-19 outcomes. Further research is required to identify patients with COPD at high risk of worse outcomes.},\r\n keywords = {Copd\r\nCovid\r\nSARS-CoV-2\r\ncoronavirus\r\nepidemiology. ,\r\nISSN = 2398-502X (Print) 2398-502x ,\r\nDOI = 10.12688/wellcomeopenres.17403.2},\r\n year = {2022},\r\n type = {Journal Article}\r\n}\r\n\r\n","author_short":["Moreno-Martos, D.","Verhamme, K.","Ostropolets, A.","Kostka, K.","Duarte-Sales, T.","Prieto-Alhambra, D.","Alshammari, T. M.","Alghoul, H.","Ahmed, W. 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