Tinea Pedis in Underrepresented Groups: An All of Us Database Analysis. Moseley, I., Ragi, S. D., Ouellette, S., & Rao, B. Mycoses, August, 2022.
Tinea Pedis in Underrepresented Groups: An All of Us Database Analysis [link]Paper  doi  abstract   bibtex   
BACKGROUND: Tinea pedis is the most common form of dermatophytosis resulting in interdigital infections. All of Us (AoU) is a National Institute of Health initiative with an emphasis on patient populations traditionally underrepresented in biomedical research. OBJECTIVES: Our objective was to evaluate the burden of tinea pedis in underrepresented groups in the United States, utilizing the novel AoU research program. METHODS: We analyzed AoU Registered Tier dataset version 5, which includes data collected between May 30, 2017 and April 1, 2021. We conducted a cross-sectional analysis linking survey and electronic health record (EHR) data to estimate the prevalence of tinea pedis in underrepresented groups. RESULTS: AoU data release includes 329,038 participants. Of these, 251,597 (76.5%) had electronic health record data and 6,932 had tinea pedis (overall prevalence, 2.76%; 95% CI, 2.69-2.82). Multivariate analyses revealed that, compared with White participants, Black and Hispanic participants had a higher adjusted odds of tinea pedis (OR, 1.29; 95% CI, 1.20-1.38 and OR, 1.38; 95% CI, 1.28-1.48, respectively). Higher adjusted odds of tinea pedis were observed in underrepresented groups defined by: age \textgreater=75 years (OR, 1.45; 95% CI, 1.33-1.57), LGBTQ status (OR, 1.17; 95% CI, 1.09-1.27), less than a high school education (OR, 1.22; 95% CI, 1.11-1.34), income \textless$35 000 (OR, 1.09; 95% CI, 1.02-1.16), and physical disability (OR, 1.56; 95% CI, 1.08-1.24). CONCLUSIONS: Our findings are consistent with overall age, and gender-specific prevalence estimates from prior epidemiologic studies, validating the scientific consistency of the new AoU database. Additionally, there may be an increased burden of tinea pedis among Black and Hispanic individuals.
@article{moseley_tinea_2022-1,
	title = {Tinea {Pedis} in {Underrepresented} {Groups}: {An} {All} of {Us} {Database} {Analysis}},
	issn = {1439-0507 (Electronic) 0933-7407 (Linking)},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/35997514},
	doi = {10.1111/myc.13522},
	abstract = {BACKGROUND: Tinea pedis is the most common form of dermatophytosis resulting in interdigital infections. All of Us (AoU) is a National Institute of Health initiative with an emphasis on patient populations traditionally underrepresented in biomedical research. OBJECTIVES: Our objective was to evaluate the burden of tinea pedis in underrepresented groups in the United States, utilizing the novel AoU research program. METHODS: We analyzed AoU Registered Tier dataset version 5, which includes data collected between May 30, 2017 and April 1, 2021. We conducted a cross-sectional analysis linking survey and electronic health record (EHR) data to estimate the prevalence of tinea pedis in underrepresented groups. RESULTS: AoU data release includes 329,038 participants. Of these, 251,597 (76.5\%) had electronic health record data and 6,932 had tinea pedis (overall prevalence, 2.76\%; 95\% CI, 2.69-2.82). Multivariate analyses revealed that, compared with White participants, Black and Hispanic participants had a higher adjusted odds of tinea pedis (OR, 1.29; 95\% CI, 1.20-1.38 and OR, 1.38; 95\% CI, 1.28-1.48, respectively). Higher adjusted odds of tinea pedis were observed in underrepresented groups defined by: age {\textgreater}=75 years (OR, 1.45; 95\% CI, 1.33-1.57), LGBTQ status (OR, 1.17; 95\% CI, 1.09-1.27), less than a high school education (OR, 1.22; 95\% CI, 1.11-1.34), income {\textless}\$35 000 (OR, 1.09; 95\% CI, 1.02-1.16), and physical disability (OR, 1.56; 95\% CI, 1.08-1.24). CONCLUSIONS: Our findings are consistent with overall age, and gender-specific prevalence estimates from prior epidemiologic studies, validating the scientific consistency of the new AoU database. Additionally, there may be an increased burden of tinea pedis among Black and Hispanic individuals.},
	journal = {Mycoses},
	author = {Moseley, I. and Ragi, S. D. and Ouellette, S. and Rao, B.},
	month = aug,
	year = {2022},
}

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