Different Pathways of Skin Aging: Objective Instrumental Evaluation. Musolff, N., Cantisani, C., Guida, S., Michelini, S., Tchack, M., Rao, B., & Pellacani, G. Diagnostics (Basel, Switzerland), 14(21):2381, October, 2024. doi abstract bibtex Background/Objectives: Hypertrophic and atrophic skin aging represent two distinct phenotypes: hypertrophic aging is marked by deep wrinkles and a leathery texture, whereas atrophic aging is characterized by overall skin thinning, increased vascularity, and a higher risk of non-melanoma skin cancers. This study aims to elucidate the characteristics and differences between hypertrophic and atrophic facial aging subtypes using two non-invasive imaging devices: VISIA® and dynamic optical coherence tomography (D-OCT). Methods: We retrospectively evaluated patients who had presented to the outpatient dermatological clinic at Policlinico Umberto I hospital in Rome, Italy for a non-invasive facial imaging check-up. We included 40 patients aged 60-75 who were imaged with VISIA® and dynamic optical coherence tomography (D-OCT). Based on the number of UV spots and amount of red found on VISIA®, subjects were grouped into four subgroups (PIGM, RED, CONTROL, PIGM + RED), and trends among them were analyzed. Results: We found a strong correlation between VISIA® red area scores and D-OCT vascular density at 300 µm depth, confirming VISIA®'s effectiveness for assessing facial vascularity. Wrinkle count was highest in areas with UV spots, particularly in the PIGM and PIGM + RED groups. Conversely, low attenuation coefficients and dermal density were observed in regions with low UV spots but high red areas. Intermediate subgroups (CONTROL and PIGM + RED) displayed varying parameters. Conclusions: Non-invasive imaging devices are effective in evaluating facial aging and distinguishing between aging subtypes. This study identified two intermediate aging types in addition to the hypertrophic and atrophic subtypes.
@article{musolff_different_2024,
title = {Different {Pathways} of {Skin} {Aging}: {Objective} {Instrumental} {Evaluation}},
volume = {14},
issn = {2075-4418},
shorttitle = {Different {Pathways} of {Skin} {Aging}},
doi = {10.3390/diagnostics14212381},
abstract = {Background/Objectives: Hypertrophic and atrophic skin aging represent two distinct phenotypes: hypertrophic aging is marked by deep wrinkles and a leathery texture, whereas atrophic aging is characterized by overall skin thinning, increased vascularity, and a higher risk of non-melanoma skin cancers. This study aims to elucidate the characteristics and differences between hypertrophic and atrophic facial aging subtypes using two non-invasive imaging devices: VISIA® and dynamic optical coherence tomography (D-OCT). Methods: We retrospectively evaluated patients who had presented to the outpatient dermatological clinic at Policlinico Umberto I hospital in Rome, Italy for a non-invasive facial imaging check-up. We included 40 patients aged 60-75 who were imaged with VISIA® and dynamic optical coherence tomography (D-OCT). Based on the number of UV spots and amount of red found on VISIA®, subjects were grouped into four subgroups (PIGM, RED, CONTROL, PIGM + RED), and trends among them were analyzed. Results: We found a strong correlation between VISIA® red area scores and D-OCT vascular density at 300 µm depth, confirming VISIA®'s effectiveness for assessing facial vascularity. Wrinkle count was highest in areas with UV spots, particularly in the PIGM and PIGM + RED groups. Conversely, low attenuation coefficients and dermal density were observed in regions with low UV spots but high red areas. Intermediate subgroups (CONTROL and PIGM + RED) displayed varying parameters. Conclusions: Non-invasive imaging devices are effective in evaluating facial aging and distinguishing between aging subtypes. This study identified two intermediate aging types in addition to the hypertrophic and atrophic subtypes.},
language = {eng},
number = {21},
journal = {Diagnostics (Basel, Switzerland)},
author = {Musolff, Noah and Cantisani, Carmen and Guida, Stefania and Michelini, Simone and Tchack, Madeline and Rao, Babar and Pellacani, Giovanni},
month = oct,
year = {2024},
pmid = {39518349},
pmcid = {PMC11545785},
keywords = {D-OCT, VISIA, non-invasive imaging, skin aging},
pages = {2381},
}
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This study aims to elucidate the characteristics and differences between hypertrophic and atrophic facial aging subtypes using two non-invasive imaging devices: VISIA® and dynamic optical coherence tomography (D-OCT). Methods: We retrospectively evaluated patients who had presented to the outpatient dermatological clinic at Policlinico Umberto I hospital in Rome, Italy for a non-invasive facial imaging check-up. We included 40 patients aged 60-75 who were imaged with VISIA® and dynamic optical coherence tomography (D-OCT). Based on the number of UV spots and amount of red found on VISIA®, subjects were grouped into four subgroups (PIGM, RED, CONTROL, PIGM + RED), and trends among them were analyzed. Results: We found a strong correlation between VISIA® red area scores and D-OCT vascular density at 300 µm depth, confirming VISIA®'s effectiveness for assessing facial vascularity. Wrinkle count was highest in areas with UV spots, particularly in the PIGM and PIGM + RED groups. Conversely, low attenuation coefficients and dermal density were observed in regions with low UV spots but high red areas. Intermediate subgroups (CONTROL and PIGM + RED) displayed varying parameters. Conclusions: Non-invasive imaging devices are effective in evaluating facial aging and distinguishing between aging subtypes. This study identified two intermediate aging types in addition to the hypertrophic and atrophic subtypes.","language":"eng","number":"21","journal":"Diagnostics (Basel, Switzerland)","author":[{"propositions":[],"lastnames":["Musolff"],"firstnames":["Noah"],"suffixes":[]},{"propositions":[],"lastnames":["Cantisani"],"firstnames":["Carmen"],"suffixes":[]},{"propositions":[],"lastnames":["Guida"],"firstnames":["Stefania"],"suffixes":[]},{"propositions":[],"lastnames":["Michelini"],"firstnames":["Simone"],"suffixes":[]},{"propositions":[],"lastnames":["Tchack"],"firstnames":["Madeline"],"suffixes":[]},{"propositions":[],"lastnames":["Rao"],"firstnames":["Babar"],"suffixes":[]},{"propositions":[],"lastnames":["Pellacani"],"firstnames":["Giovanni"],"suffixes":[]}],"month":"October","year":"2024","pmid":"39518349","pmcid":"PMC11545785","keywords":"D-OCT, VISIA, non-invasive imaging, skin aging","pages":"2381","bibtex":"@article{musolff_different_2024,\n\ttitle = {Different {Pathways} of {Skin} {Aging}: {Objective} {Instrumental} {Evaluation}},\n\tvolume = {14},\n\tissn = {2075-4418},\n\tshorttitle = {Different {Pathways} of {Skin} {Aging}},\n\tdoi = {10.3390/diagnostics14212381},\n\tabstract = {Background/Objectives: Hypertrophic and atrophic skin aging represent two distinct phenotypes: hypertrophic aging is marked by deep wrinkles and a leathery texture, whereas atrophic aging is characterized by overall skin thinning, increased vascularity, and a higher risk of non-melanoma skin cancers. This study aims to elucidate the characteristics and differences between hypertrophic and atrophic facial aging subtypes using two non-invasive imaging devices: VISIA® and dynamic optical coherence tomography (D-OCT). Methods: We retrospectively evaluated patients who had presented to the outpatient dermatological clinic at Policlinico Umberto I hospital in Rome, Italy for a non-invasive facial imaging check-up. We included 40 patients aged 60-75 who were imaged with VISIA® and dynamic optical coherence tomography (D-OCT). Based on the number of UV spots and amount of red found on VISIA®, subjects were grouped into four subgroups (PIGM, RED, CONTROL, PIGM + RED), and trends among them were analyzed. Results: We found a strong correlation between VISIA® red area scores and D-OCT vascular density at 300 µm depth, confirming VISIA®'s effectiveness for assessing facial vascularity. Wrinkle count was highest in areas with UV spots, particularly in the PIGM and PIGM + RED groups. Conversely, low attenuation coefficients and dermal density were observed in regions with low UV spots but high red areas. Intermediate subgroups (CONTROL and PIGM + RED) displayed varying parameters. Conclusions: Non-invasive imaging devices are effective in evaluating facial aging and distinguishing between aging subtypes. This study identified two intermediate aging types in addition to the hypertrophic and atrophic subtypes.},\n\tlanguage = {eng},\n\tnumber = {21},\n\tjournal = {Diagnostics (Basel, Switzerland)},\n\tauthor = {Musolff, Noah and Cantisani, Carmen and Guida, Stefania and Michelini, Simone and Tchack, Madeline and Rao, Babar and Pellacani, Giovanni},\n\tmonth = oct,\n\tyear = {2024},\n\tpmid = {39518349},\n\tpmcid = {PMC11545785},\n\tkeywords = {D-OCT, VISIA, non-invasive imaging, skin aging},\n\tpages = {2381},\n}\n\n\n\n","author_short":["Musolff, N.","Cantisani, C.","Guida, S.","Michelini, S.","Tchack, M.","Rao, B.","Pellacani, G."],"key":"musolff_different_2024","id":"musolff_different_2024","bibbaseid":"musolff-cantisani-guida-michelini-tchack-rao-pellacani-differentpathwaysofskinagingobjectiveinstrumentalevaluation-2024","role":"author","urls":{},"keyword":["D-OCT","VISIA","non-invasive imaging","skin aging"],"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/raoresearch","dataSources":["aGgndugSyribdb2rd"],"keywords":["d-oct","visia","non-invasive imaging","skin aging"],"search_terms":["different","pathways","skin","aging","objective","instrumental","evaluation","musolff","cantisani","guida","michelini","tchack","rao","pellacani"],"title":"Different Pathways of Skin Aging: Objective Instrumental Evaluation","year":2024}