@article{naik_stability_2017,
	title = {Stability of heat stable, live attenuated {Rotavirus} vaccine ({ROTASIIL}®)},
	issn = {1873-2518},
	doi = {10.1016/j.vaccine.2017.04.025},
	abstract = {Vaccines currently available across the globe are stored and transported in a continuous cold-chain at 2-8°C or below -20°C. A temperature excursion outside this range affects the potency of the vaccines. Such vaccines need to be discarded leading wastage. The Rotavirus disease burden is predominantly reported in developing and low-income countries and therefore, has entered or poised to enter their national immunization programs. These countries already have several limitations for effective storage, maintenance and distribution of vaccines in a cold-chain and this introduction is expected to further stress this fragile ecosystem. To help mitigate the cold chain related issues, SIIPL has developed a thermostable rotavirus vaccine ROTASIIL® which can be stored at a temperature below 25°C for 36months, completely by-passing the standard 2-8°C cold storages. In addition it has the capability to withstand temperatures of 37°C and 40°C for 18months and short term exposure to 55°C. It can also tolerate a temperature shock of being thawed from an extreme cold temperature of -20°C to a high temperature of 42°C. The vaccine contains serotypes G1, G2, G3, G4 and G9 (UK-Bovine reassortant strains procured from National Institute of Health-USA). The vaccine is recently licensed in India.},
	language = {eng},
	journal = {Vaccine},
	author = {Naik, Sameer P. and Zade, Jagdish K. and Sabale, Rajendra N. and Pisal, Sambhaji S. and Menon, Ravi and Bankar, Subhash G. and Gairola, Sunil and Dhere, Rajeev M.},
	month = apr,
	year = {2017},
	pmid = {28434688},
}

{"_id":"xzKFt6MmTjopabJRb","bibbaseid":"naik-zade-sabale-pisal-menon-bankar-gairola-dhere-stabilityofheatstableliveattenuatedrotavirusvaccinerotasiil-2017","author_short":["Naik, S. P.","Zade, J. K.","Sabale, R. N.","Pisal, S. S.","Menon, R.","Bankar, S. G.","Gairola, S.","Dhere, R. M."],"bibdata":{"bibtype":"article","type":"article","title":"Stability of heat stable, live attenuated Rotavirus vaccine (ROTASIIL®)","issn":"1873-2518","doi":"10.1016/j.vaccine.2017.04.025","abstract":"Vaccines currently available across the globe are stored and transported in a continuous cold-chain at 2-8°C or below -20°C. A temperature excursion outside this range affects the potency of the vaccines. Such vaccines need to be discarded leading wastage. The Rotavirus disease burden is predominantly reported in developing and low-income countries and therefore, has entered or poised to enter their national immunization programs. These countries already have several limitations for effective storage, maintenance and distribution of vaccines in a cold-chain and this introduction is expected to further stress this fragile ecosystem. To help mitigate the cold chain related issues, SIIPL has developed a thermostable rotavirus vaccine ROTASIIL® which can be stored at a temperature below 25°C for 36months, completely by-passing the standard 2-8°C cold storages. In addition it has the capability to withstand temperatures of 37°C and 40°C for 18months and short term exposure to 55°C. It can also tolerate a temperature shock of being thawed from an extreme cold temperature of -20°C to a high temperature of 42°C. The vaccine contains serotypes G1, G2, G3, G4 and G9 (UK-Bovine reassortant strains procured from National Institute of Health-USA). The vaccine is recently licensed in India.","language":"eng","journal":"Vaccine","author":[{"propositions":[],"lastnames":["Naik"],"firstnames":["Sameer","P."],"suffixes":[]},{"propositions":[],"lastnames":["Zade"],"firstnames":["Jagdish","K."],"suffixes":[]},{"propositions":[],"lastnames":["Sabale"],"firstnames":["Rajendra","N."],"suffixes":[]},{"propositions":[],"lastnames":["Pisal"],"firstnames":["Sambhaji","S."],"suffixes":[]},{"propositions":[],"lastnames":["Menon"],"firstnames":["Ravi"],"suffixes":[]},{"propositions":[],"lastnames":["Bankar"],"firstnames":["Subhash","G."],"suffixes":[]},{"propositions":[],"lastnames":["Gairola"],"firstnames":["Sunil"],"suffixes":[]},{"propositions":[],"lastnames":["Dhere"],"firstnames":["Rajeev","M."],"suffixes":[]}],"month":"April","year":"2017","pmid":"28434688","bibtex":"@article{naik_stability_2017,\n\ttitle = {Stability of heat stable, live attenuated {Rotavirus} vaccine ({ROTASIIL}®)},\n\tissn = {1873-2518},\n\tdoi = {10.1016/j.vaccine.2017.04.025},\n\tabstract = {Vaccines currently available across the globe are stored and transported in a continuous cold-chain at 2-8°C or below -20°C. A temperature excursion outside this range affects the potency of the vaccines. Such vaccines need to be discarded leading wastage. The Rotavirus disease burden is predominantly reported in developing and low-income countries and therefore, has entered or poised to enter their national immunization programs. These countries already have several limitations for effective storage, maintenance and distribution of vaccines in a cold-chain and this introduction is expected to further stress this fragile ecosystem. To help mitigate the cold chain related issues, SIIPL has developed a thermostable rotavirus vaccine ROTASIIL® which can be stored at a temperature below 25°C for 36months, completely by-passing the standard 2-8°C cold storages. In addition it has the capability to withstand temperatures of 37°C and 40°C for 18months and short term exposure to 55°C. It can also tolerate a temperature shock of being thawed from an extreme cold temperature of -20°C to a high temperature of 42°C. The vaccine contains serotypes G1, G2, G3, G4 and G9 (UK-Bovine reassortant strains procured from National Institute of Health-USA). The vaccine is recently licensed in India.},\n\tlanguage = {eng},\n\tjournal = {Vaccine},\n\tauthor = {Naik, Sameer P. and Zade, Jagdish K. and Sabale, Rajendra N. and Pisal, Sambhaji S. and Menon, Ravi and Bankar, Subhash G. and Gairola, Sunil and Dhere, Rajeev M.},\n\tmonth = apr,\n\tyear = {2017},\n\tpmid = {28434688},\n}\n\n","author_short":["Naik, S. P.","Zade, J. K.","Sabale, R. N.","Pisal, S. S.","Menon, R.","Bankar, S. G.","Gairola, S.","Dhere, R. M."],"key":"naik_stability_2017","id":"naik_stability_2017","bibbaseid":"naik-zade-sabale-pisal-menon-bankar-gairola-dhere-stabilityofheatstableliveattenuatedrotavirusvaccinerotasiil-2017","role":"author","urls":{},"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/zotero/robin.marlow","dataSources":["ix72eqAAMGCuupBaz"],"keywords":[],"search_terms":["stability","heat","stable","live","attenuated","rotavirus","vaccine","rotasiil","naik","zade","sabale","pisal","menon","bankar","gairola","dhere"],"title":"Stability of heat stable, live attenuated Rotavirus vaccine (ROTASIIL®)","year":2017}