The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. Nasreddine, Z. S., Phillips, N. A., Bédirian, V., Charbonneau, S., Whitehead, V., Collin, I., Cummings, J. L., & Chertkow, H. Journal of the American Geriatrics Society, 53(4):695–699, April, 2005.
doi  abstract   bibtex   
OBJECTIVES: To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia. DESIGN: Validation study. SETTING: A community clinic and an academic center. PARTICIPANTS: Ninety-four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini-Mental State Examination (MMSE) score \textgreater or =17), and 90 healthy elderly controls (NC). MEASUREMENTS: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD. RESULTS: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively). CONCLUSION: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.
@article{nasreddine_montreal_2005,
	title = {The {Montreal} {Cognitive} {Assessment}, {MoCA}: a brief screening tool for mild cognitive impairment},
	volume = {53},
	issn = {0002-8614},
	shorttitle = {The {Montreal} {Cognitive} {Assessment}, {MoCA}},
	doi = {10.1111/j.1532-5415.2005.53221.x},
	abstract = {OBJECTIVES: To develop a 10-minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first-line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.
DESIGN: Validation study.
SETTING: A community clinic and an academic center.
PARTICIPANTS: Ninety-four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini-Mental State Examination (MMSE) score {\textgreater} or =17), and 90 healthy elderly controls (NC).
MEASUREMENTS: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD.
RESULTS: Using a cutoff score 26, the MMSE had a sensitivity of 18\% to detect MCI, whereas the MoCA detected 90\% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78\%, whereas the MoCA detected 100\%. Specificity was excellent for both MMSE and MoCA (100\% and 87\%, respectively).
CONCLUSION: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.},
	language = {eng},
	number = {4},
	journal = {Journal of the American Geriatrics Society},
	author = {Nasreddine, Ziad S. and Phillips, Natalie A. and Bédirian, Valérie and Charbonneau, Simon and Whitehead, Victor and Collin, Isabelle and Cummings, Jeffrey L. and Chertkow, Howard},
	month = apr,
	year = {2005},
	pmid = {15817019},
	keywords = {Aged, Alzheimer Disease, Case-Control Studies, Cognition Disorders, Female, Humans, Male, Neuropsychological Tests, Psychometrics, Quebec, Reproducibility of Results, Sensitivity and Specificity},
	pages = {695--699}
}

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