A study using irreversible electroporation to treat large, irregular tumors in a canine patient. Neal, R. E., Garcia, P. A., Rossmeisl, J. H., & Davalos, R. V. Annu Int Conf IEEE Eng Med Biol Soc, 2010:2747-50, 2010. Neal, Robert E Garcia, Paulo A Rossmeisl, John H Davalos, Rafael V Journal Article Research Support, Non-U.S. Gov't United States 2010/11/26 Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:2747-50. doi: 10.1109/IEMBS.2010.5626372.
doi  abstract   bibtex   
Irreversible electroporation (IRE) has shown promise for the therapeutic treatment of focal disease, including tumors. The effects of treatment are dependent on the electric field distribution, which may be predicted with numerical modeling. In order to improve the effectiveness and scope of IRE therapies, techniques must be developed for designing protocols capable of treating large and irregular tumors. We present the findings of a study designing an IRE treatment plan for a canine patient using medical imaging analysis and reconstruction, numerical modeling, and real-time electrode placement guidance. The executed plan was able to alleviate the patient's clinical symptoms without damaging any of the nearby sensitive tissues in a complex heterogeneous environment.
@article{RN227,
   author = {Neal, R. E. and Garcia, P. A. and Rossmeisl, J. H. and Davalos, R. V.},
   title = {A study using irreversible electroporation to treat large, irregular tumors in a canine patient},
   journal = {Annu Int Conf IEEE Eng Med Biol Soc},
   volume = {2010},
   pages = {2747-50},
   note = {Neal, Robert E
Garcia, Paulo A
Rossmeisl, John H
Davalos, Rafael V
Journal Article
Research Support, Non-U.S. Gov't
United States
2010/11/26
Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:2747-50. doi: 10.1109/IEMBS.2010.5626372.},
   abstract = {Irreversible electroporation (IRE) has shown promise for the therapeutic treatment of focal disease, including tumors. The effects of treatment are dependent on the electric field distribution, which may be predicted with numerical modeling. In order to improve the effectiveness and scope of IRE therapies, techniques must be developed for designing protocols capable of treating large and irregular tumors. We present the findings of a study designing an IRE treatment plan for a canine patient using medical imaging analysis and reconstruction, numerical modeling, and real-time electrode placement guidance. The executed plan was able to alleviate the patient's clinical symptoms without damaging any of the nearby sensitive tissues in a complex heterogeneous environment.},
   keywords = {Algorithms
Animals
Bone Neoplasms/*therapy/veterinary
Diagnostic Imaging
Dogs
Electroporation/*methods
Femur/pathology
Image Processing, Computer-Assisted/methods
Medical Oncology/methods
Models, Theoretical
Quality of Life
Sarcoma/*therapy/veterinary
Tomography, X-Ray Computed/methods},
   ISSN = {2375-7477 (Print)
2375-7477},
   DOI = {10.1109/iembs.2010.5626372},
   year = {2010},
   type = {Journal Article}
}

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