Patient-centric research in the time of COVID-19: conducting ethical COVID-19 research in Africa. Nembaware, V., Munung, N. S., Matimba, A., & Tiffin, N. BMJ Global Health, 5(8):e003035, BMJ Specialist Journals, aug, 2020.
Patient-centric research in the time of COVID-19: conducting ethical COVID-19 research in Africa [link]Paper  doi  abstract   bibtex   
### Summary box Without effective management, COVID-19 could be catastrophic in Africa, exacerbated by high infectious and non-infectious disease burdens, poor healthcare access and limited health resources.1 Projections estimate over 110 million infections and 300 000 mortalities in sub-Saharan Africa alone.2 Global evidence identifies contributing risk factors such as age, gender and existing comorbidities, but drivers of disease severity and poor survival in some patients are still unclear.3 African genetic variation underlies many differences in pathogen susceptibility, disease severity, drug response and patient outcomes compared with rest-of-world populations.4 5 African COVID-19 disease profiles may also differ given unique regional environmental challenges, population structure and genetic make-up, and potential proliferation of specific virus strains, limiting transferability of research findings from other continents. An urgent pandemic response is driving rapid assembly of COVID-19 research programmes, accelerated ethics review by Institutional Review Boards …
@article{Nembaware2020,
abstract = {{\#}{\#}{\#} Summary box Without effective management, COVID-19 could be catastrophic in Africa, exacerbated by high infectious and non-infectious disease burdens, poor healthcare access and limited health resources.1 Projections estimate over 110 million infections and 300 000 mortalities in sub-Saharan Africa alone.2 Global evidence identifies contributing risk factors such as age, gender and existing comorbidities, but drivers of disease severity and poor survival in some patients are still unclear.3 African genetic variation underlies many differences in pathogen susceptibility, disease severity, drug response and patient outcomes compared with rest-of-world populations.4 5 African COVID-19 disease profiles may also differ given unique regional environmental challenges, population structure and genetic make-up, and potential proliferation of specific virus strains, limiting transferability of research findings from other continents. An urgent pandemic response is driving rapid assembly of COVID-19 research programmes, accelerated ethics review by Institutional Review Boards {\ldots}},
author = {Nembaware, Victoria and Munung, Nchangwi Syntia and Matimba, Alice and Tiffin, Nicki},
doi = {10.1136/bmjgh-2020-003035},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Nembaware et al. - 2020 - Patient-centric research in the time of COVID-19 conducting ethical COVID-19 research in Africa.pdf:pdf},
issn = {2059-7908},
journal = {BMJ Global Health},
keywords = {OA,commentary,fund{\_}ack},
mendeley-tags = {OA,commentary,fund{\_}ack},
month = {aug},
number = {8},
pages = {e003035},
pmid = {32764129},
publisher = {BMJ Specialist Journals},
title = {{Patient-centric research in the time of COVID-19: conducting ethical COVID-19 research in Africa}},
url = {http://gh.bmj.com/lookup/doi/10.1136/bmjgh-2020-003035},
volume = {5},
year = {2020}
}

Downloads: 0