Uptake of plutonium by the human liver. Newton, D., Talbot, R., J., Kang, C., & Warner, A., J. Radiation Protection Dosimetry, 80(4):385-395, 1998.
abstract   bibtex   
The hepatic uptake of /sup 237/Pu in 12 healthy subjects who received it intravenously as Pu(IV) citrate is reported. The results were derived from the response of a scintillation counter viewing the right lateral surfaces of the lower thorax; calibration for individual subjects was performed with /sup 237/Pu-loaded phantoms based on anatomical data from magnetic resonance imaging. The highest levels (mean 73+or-12 (sd) % of injection) were reached variously after 7-230 days, with no conclusive evidence of a subsequent reduction; half of the accumulation occurred within 1-2 days. This uptake is much greater than predicted by the ICRP's present or previous metabolic models for plutonium, but the excess is strongly corroborated by other data from this study.
@article{
 title = {Uptake of plutonium by the human liver},
 type = {article},
 year = {1998},
 keywords = {/sup 237/Pu,/sup 237/Pu-loaded phantoms,Accumulation,Anatomical data,Biomedical MRI,Biotransport,Calibration,Health hazards,Healthy subjects,Hepatic uptake,Human liver,Individual subjects,Liver,Lower thorax,Magnetic resonance imaging,Metabolic models,Plutonium,Pu,Pu(IV) citrate,Radioisotopes,Right lateral surfaces,Scintillation counter},
 pages = {385-395},
 volume = {80},
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 last_modified = {2015-02-12T20:21:04.000Z},
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 notes = {<m:note>Article<m:linebreak/>Nuclear Technology Publishing</m:note>},
 abstract = {The hepatic uptake of /sup 237/Pu in 12 healthy subjects who received it intravenously as Pu(IV) citrate is reported. The results were derived from the response of a scintillation counter viewing the right lateral surfaces of the lower thorax; calibration for individual subjects was performed with /sup 237/Pu-loaded phantoms based on anatomical data from magnetic resonance imaging. The highest levels (mean 73+or-12 (sd) % of injection) were reached variously after 7-230 days, with no conclusive evidence of a subsequent reduction; half of the accumulation occurred within 1-2 days. This uptake is much greater than predicted by the ICRP's present or previous metabolic models for plutonium, but the excess is strongly corroborated by other data from this study.},
 bibtype = {article},
 author = {Newton, D and Talbot, R J and Kang, C and Warner, A J},
 journal = {Radiation Protection Dosimetry},
 number = {4}
}

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