TOM software toolbox: acquisition and analysis for electron tomography. Nickell, S., Förster, F., Linaroudis, A., Net, W., D., Beck, F., Hegerl, R., Baumeister, W., & Plitzko, J., M. Journal of structural biology, 149(3):227-34, 3, 2005.
TOM software toolbox: acquisition and analysis for electron tomography. [pdf]Paper  TOM software toolbox: acquisition and analysis for electron tomography. [link]Website  abstract   bibtex   
Automated data acquisition procedures have changed the perspectives of electron tomography (ET) in a profound manner. Elaborate data acquisition schemes with autotuning functions minimize exposure of the specimen to the electron beam and sophisticated image analysis routines retrieve a maximum of information from noisy data sets. "TOM software toolbox" integrates established algorithms and new concepts tailored to the special needs of low dose ET. It provides a user-friendly unified platform for all processing steps: acquisition, alignment, reconstruction, and analysis. Designed as a collection of computational procedures it is a complete software solution within a highly flexible framework. TOM represents a new way of working with the electron microscope and can serve as the basis for future high-throughput applications.

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