Notes on inhibition in LGN. Niebur, E. 1997.
@unpublished{ Niebur97b,
  author = {Niebur, E.},
  title = {Notes on inhibition in LGN},
  year = {1997},
  downloads = {Niebur97b.pdf; },
  full_text = {From: Ernst Niebur <>; To:
	do you know if (ref'ces) someone has studied the role of LGN circuitry
	( particularly, GABAergic influences: interneurons and recticularis
	neurons) on sensory throughput in thalamus? on RFs? etc‥‥ studied=
	expts and/or computational models? Especially, with biophysically-based
	(HH-type cells) computational models‥.
	hm, that's funny, I guess if I had had this question, I would have
	asked _you_ about it :) but let's see what I can remember and dig
	up in my file cabinet:
	A classic seems to be Wolf Singer's review (Physiol. Reviews 57(3),
	386-420, 1977) which I am sure you are familiar with. He has some
	paragraphs on inhibitory interactions.
	Vidyasagar and Urbas (EBR 46, 157-169, 1982) and Vidyasagar(ibid,
	55, 192-195, 1984) claimed that intra-LGN inhibition is responsible
	for LGN orientation sensitivity (in cat). Their claim was refuted
	by Soodak et al, J. Neurophysiol 58(2), 1987, 267-275 who claimed
	that the small orientation bias is completely due to retinal input.
	I believe that this was also Audy Leventhal's take but I forgot the
	More general effects of intra-LGN inhibitory circuits on receptive
	field structures of LGN relay cells were studied by Norton, Holdefer
	and Godwin (Brain Research 488, 341-347, 1989; ibid, 348-352) in
	the tree shrew. They claim changes in receptive field center sensitivity
	and signal detectability.
	Interactions BETWEEN the LGN inhibitory pathways (intrageniculate
	and perigeniculate) were studied by Ahlsen, Lindstrom and Lo (EBR
	58: 134-143, 1985). As far as the final influence on sensory throughput
	is concerned, they interpret their results as supporting gain control
	An anatomical paper by Weber et al (J. Comp. Neurology 289:156-164,
	1989) finds that the inhibitory interneurons receive input from corticofugal
	feedback (in cat). They hypothesize that this modulates (via the
	activity of the inhibitory interneurons) the responses of relay cells
	to input from the retina.
	Finally, Funke and Worgotter (J. Physiol 485.3, 715-737, 1995) measured
	the temporal structure of LGN spike trains (cat again) and suggested
	an inhibitory intra-LGN circuit for the explanation of the structure.
	Their functional interpretation regarding sensory throughput is that
	of a NAND gate. They also did some simulations but their neuron models
	were very simple.},
  opten_number = {3.4.2:57},
  optmonth = {July}

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