@inproceedings{nikolaev2005general,
  title={A general hybrid optimization framework for the optimal modulation of enzyme levels using large-scale kinetic models of bacterial metabolism},
  author={Nikolaev, Evgeni and Pharkya, Priti and Armaou, Antonios and Maranas, Costas D},
  booktitle={05AIChE: 2005 AIChE Annual Meeting and Fall Showcase},
  year={2005}
}

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