3D myocardial T $_{\textrm{1}}$ mapping using saturation recovery: 3D Free-Breathing Myocardial T $

3D myocardial T $_{\textrm{1}}$ mapping using saturation recovery: 3D Free-Breathing Myocardial T $_{\textrm{1}}$ Mapping. Nordio, G., Henningsson, M., Chiribiri, A., Villa, A. D., Schneider, T., & Botnar, R. M. Journal of Magnetic Resonance Imaging, 46(1):218–227, July, 2017.
$3D myocardial T $_{\textrm{1}}$ mapping using saturation recovery: 3D Free-Breathing Myocardial T $_{\textrm{1}}$ Mapping [link]$ Paper doi abstract bibtex

Purpose: To propose a 3D quantitative high-resolution T1 mapping technique, called 3D SASHA (saturation-recovery single-shot acquisition), which combines a saturation recovery pulse with 1D-navigator-based-respiratory motion compensation to acquire the whole volume of the heart in free breathing. The sequence was tested and validated both in a T1 phantom and in healthy subjects. Materials and Methods: The 3D SASHA method was implemented on a 1.5T scanner. A diaphragmatic navigator was used to allow free-breathing acquisition and the images were acquired with a resolution of 1.4 3 1.4 3 8 mm3. For assessment of accuracy and precision the sequence was compared with the reference gold-standard inversion-recovery spin echo (IRSE) pulse sequence in a T1 phantom, while for the in vivo studies (10 healthy volunteers) 3D SASHA was compared with the clinically used 2D MOLLI (3-3-5) and 2D SASHA protocols. Results: There was good agreement between the T1 values measured in a T1 phantom with 3D SASHA and the reference IRSE pulse sequences (1111.6 6 31 msec vs. 1123.6 6 8 msec, P 5 0.9947). Mean and standard deviation of the myocardial T1 values in healthy subjects measured with 2D MOLLI, 2D SASHA, and 3D SASHA sequences were 881 6 40 msec, 1181.3 6 32 msec, and 1153.6 6 28 msec respectively. Conclusion: The proposed 3D SASHA sequence allows for high-resolution free-breathing whole-heart T1-mapping with T1 values in good agreement with the 2D SASHA and improved precision. Level of Evidence: 2

@article{nordio_3d_2017,
	title = {{3D} myocardial \textit{{T}} $_{\textrm{1}}$ mapping using saturation recovery: {3D} {Free}-{Breathing} {Myocardial} \textit{{T}} $_{\textrm{1}}$ {Mapping}},
	volume = {46},
	issn = {10531807},
	shorttitle = {{3D} myocardial \textit{{T}} $_{\textrm{1}}$ mapping using saturation recovery},
	url = {https://onlinelibrary.wiley.com/doi/10.1002/jmri.25575},
	doi = {10.1002/jmri.25575},
	abstract = {Purpose: To propose a 3D quantitative high-resolution T1 mapping technique, called 3D SASHA (saturation-recovery single-shot acquisition), which combines a saturation recovery pulse with 1D-navigator-based-respiratory motion compensation to acquire the whole volume of the heart in free breathing. The sequence was tested and validated both in a T1 phantom and in healthy subjects. Materials and Methods: The 3D SASHA method was implemented on a 1.5T scanner. A diaphragmatic navigator was used to allow free-breathing acquisition and the images were acquired with a resolution of 1.4 3 1.4 3 8 mm3. For assessment of accuracy and precision the sequence was compared with the reference gold-standard inversion-recovery spin echo (IRSE) pulse sequence in a T1 phantom, while for the in vivo studies (10 healthy volunteers) 3D SASHA was compared with the clinically used 2D MOLLI (3-3-5) and 2D SASHA protocols.
Results: There was good agreement between the T1 values measured in a T1 phantom with 3D SASHA and the reference IRSE pulse sequences (1111.6 6 31 msec vs. 1123.6 6 8 msec, P 5 0.9947). Mean and standard deviation of the myocardial T1 values in healthy subjects measured with 2D MOLLI, 2D SASHA, and 3D SASHA sequences were 881 6 40 msec, 1181.3 6 32 msec, and 1153.6 6 28 msec respectively.
Conclusion: The proposed 3D SASHA sequence allows for high-resolution free-breathing whole-heart T1-mapping with T1 values in good agreement with the 2D SASHA and improved precision. Level of Evidence: 2},
	language = {en},
	number = {1},
	urldate = {2022-03-31},
	journal = {Journal of Magnetic Resonance Imaging},
	author = {Nordio, Giovanna and Henningsson, Markus and Chiribiri, Amedeo and Villa, Adriana D.M. and Schneider, Torben and Botnar, René M.},
	month = jul,
	year = {2017},
	pages = {218--227},
}

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The sequence was tested and validated both in a T1 phantom and in healthy subjects. Materials and Methods: The 3D SASHA method was implemented on a 1.5T scanner. A diaphragmatic navigator was used to allow free-breathing acquisition and the images were acquired with a resolution of 1.4 3 1.4 3 8 mm3. For assessment of accuracy and precision the sequence was compared with the reference gold-standard inversion-recovery spin echo (IRSE) pulse sequence in a T1 phantom, while for the in vivo studies (10 healthy volunteers) 3D SASHA was compared with the clinically used 2D MOLLI (3-3-5) and 2D SASHA protocols. Results: There was good agreement between the T1 values measured in a T1 phantom with 3D SASHA and the reference IRSE pulse sequences (1111.6 6 31 msec vs. 1123.6 6 8 msec, P 5 0.9947). Mean and standard deviation of the myocardial T1 values in healthy subjects measured with 2D MOLLI, 2D SASHA, and 3D SASHA sequences were 881 6 40 msec, 1181.3 6 32 msec, and 1153.6 6 28 msec respectively. Conclusion: The proposed 3D SASHA sequence allows for high-resolution free-breathing whole-heart T1-mapping with T1 values in good agreement with the 2D SASHA and improved precision. Level of Evidence: 2","language":"en","number":"1","urldate":"2022-03-31","journal":"Journal of Magnetic Resonance Imaging","author":[{"propositions":[],"lastnames":["Nordio"],"firstnames":["Giovanna"],"suffixes":[]},{"propositions":[],"lastnames":["Henningsson"],"firstnames":["Markus"],"suffixes":[]},{"propositions":[],"lastnames":["Chiribiri"],"firstnames":["Amedeo"],"suffixes":[]},{"propositions":[],"lastnames":["Villa"],"firstnames":["Adriana","D.M."],"suffixes":[]},{"propositions":[],"lastnames":["Schneider"],"firstnames":["Torben"],"suffixes":[]},{"propositions":[],"lastnames":["Botnar"],"firstnames":["René","M."],"suffixes":[]}],"month":"July","year":"2017","pages":"218–227","bibtex":"@article{nordio_3d_2017,\n\ttitle = {{3D} myocardial \\textit{{T}} $_{\\textrm{1}}$ mapping using saturation recovery: {3D} {Free}-{Breathing} {Myocardial} \\textit{{T}} $_{\\textrm{1}}$ {Mapping}},\n\tvolume = {46},\n\tissn = {10531807},\n\tshorttitle = {{3D} myocardial \\textit{{T}} $_{\\textrm{1}}$ mapping using saturation recovery},\n\turl = {https://onlinelibrary.wiley.com/doi/10.1002/jmri.25575},\n\tdoi = {10.1002/jmri.25575},\n\tabstract = {Purpose: To propose a 3D quantitative high-resolution T1 mapping technique, called 3D SASHA (saturation-recovery single-shot acquisition), which combines a saturation recovery pulse with 1D-navigator-based-respiratory motion compensation to acquire the whole volume of the heart in free breathing. The sequence was tested and validated both in a T1 phantom and in healthy subjects. Materials and Methods: The 3D SASHA method was implemented on a 1.5T scanner. A diaphragmatic navigator was used to allow free-breathing acquisition and the images were acquired with a resolution of 1.4 3 1.4 3 8 mm3. For assessment of accuracy and precision the sequence was compared with the reference gold-standard inversion-recovery spin echo (IRSE) pulse sequence in a T1 phantom, while for the in vivo studies (10 healthy volunteers) 3D SASHA was compared with the clinically used 2D MOLLI (3-3-5) and 2D SASHA protocols.\nResults: There was good agreement between the T1 values measured in a T1 phantom with 3D SASHA and the reference IRSE pulse sequences (1111.6 6 31 msec vs. 1123.6 6 8 msec, P 5 0.9947). 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