Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: A factor of potential importance for auxin–cytokinin-regulated development. Nordström, A., Tarkowski, P., Tarkowska, D., Norbaek, R., Åstot, C., Dolezal, K., & Sandberg, G. Proceedings of the National Academy of Sciences, 101(21):8039–8044, May, 2004. Publisher: National Academy of Sciences Section: Biological Sciences![Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: A factor of potential importance for auxin–cytokinin-regulated development [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex One of the most long-lived models in plant science is the belief that the long-distance transport and ratio of two plant hormones, auxin and cytokinin, at the site of action control major developmental events such as apical dominance. We have used in vivo deuterium labeling and mass spectrometry to investigate the dynamics of homeostatic cross talk between the two plant hormones. Interestingly, auxin mediates a very rapid negative control of the cytokinin pool by mainly suppressing the biosynthesis via the isopentenyladenosine-5′-monophosphate-independent pathway. In contrast, the effect of cytokinin overproduction on the entire auxin pool in the plant was slower, indicating that this most likely is mediated through altered development. In addition, we were able to confirm that the lateral root meristems are likely to be the main sites of isopentenyladenosine-5′-monophosphate-dependent cytokinin synthesis, and that the aerial tissue of the plant surprisingly also was a significant source of cytokinin biosynthesis. Our demonstration of shoot-localized synthesis, together with data demonstrating that auxin imposes a very rapid regulation of cytokinin biosynthesis, illustrates that the two hormones can interact also on the metabolic level in controlling plant development, and that the aerial part of the plant has the capacity to synthesize its own cytokinin independent of long-range transport from the root system.
@article{nordstrom_auxin_2004,
title = {Auxin regulation of cytokinin biosynthesis in {Arabidopsis} thaliana: {A} factor of potential importance for auxin–cytokinin-regulated development},
volume = {101},
copyright = {Copyright © 2004, The National Academy of Sciences},
issn = {0027-8424, 1091-6490},
shorttitle = {Auxin regulation of cytokinin biosynthesis in {Arabidopsis} thaliana},
url = {https://www.pnas.org/content/101/21/8039},
doi = {10/c2tzk7},
abstract = {One of the most long-lived models in plant science is the belief that the long-distance transport and ratio of two plant hormones, auxin and cytokinin, at the site of action control major developmental events such as apical dominance. We have used in vivo deuterium labeling and mass spectrometry to investigate the dynamics of homeostatic cross talk between the two plant hormones. Interestingly, auxin mediates a very rapid negative control of the cytokinin pool by mainly suppressing the biosynthesis via the isopentenyladenosine-5′-monophosphate-independent pathway. In contrast, the effect of cytokinin overproduction on the entire auxin pool in the plant was slower, indicating that this most likely is mediated through altered development. In addition, we were able to confirm that the lateral root meristems are likely to be the main sites of isopentenyladenosine-5′-monophosphate-dependent cytokinin synthesis, and that the aerial tissue of the plant surprisingly also was a significant source of cytokinin biosynthesis. Our demonstration of shoot-localized synthesis, together with data demonstrating that auxin imposes a very rapid regulation of cytokinin biosynthesis, illustrates that the two hormones can interact also on the metabolic level in controlling plant development, and that the aerial part of the plant has the capacity to synthesize its own cytokinin independent of long-range transport from the root system.},
language = {en},
number = {21},
urldate = {2021-06-15},
journal = {Proceedings of the National Academy of Sciences},
author = {Nordström, Anders and Tarkowski, Petr and Tarkowska, Danuse and Norbaek, Rikke and Åstot, Crister and Dolezal, Karel and Sandberg, Göran},
month = may,
year = {2004},
pmid = {15146070},
note = {Publisher: National Academy of Sciences
Section: Biological Sciences},
pages = {8039--8044},
}
Downloads: 0
{"_id":"4i5DEhzzwi44eiS7W","bibbaseid":"nordstrm-tarkowski-tarkowska-norbaek-stot-dolezal-sandberg-auxinregulationofcytokininbiosynthesisinarabidopsisthalianaafactorofpotentialimportanceforauxincytokininregulateddevelopment-2004","author_short":["Nordström, A.","Tarkowski, P.","Tarkowska, D.","Norbaek, R.","Åstot, C.","Dolezal, K.","Sandberg, G."],"bibdata":{"bibtype":"article","type":"article","title":"Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: A factor of potential importance for auxin–cytokinin-regulated development","volume":"101","copyright":"Copyright © 2004, The National Academy of Sciences","issn":"0027-8424, 1091-6490","shorttitle":"Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana","url":"https://www.pnas.org/content/101/21/8039","doi":"10/c2tzk7","abstract":"One of the most long-lived models in plant science is the belief that the long-distance transport and ratio of two plant hormones, auxin and cytokinin, at the site of action control major developmental events such as apical dominance. We have used in vivo deuterium labeling and mass spectrometry to investigate the dynamics of homeostatic cross talk between the two plant hormones. Interestingly, auxin mediates a very rapid negative control of the cytokinin pool by mainly suppressing the biosynthesis via the isopentenyladenosine-5′-monophosphate-independent pathway. In contrast, the effect of cytokinin overproduction on the entire auxin pool in the plant was slower, indicating that this most likely is mediated through altered development. In addition, we were able to confirm that the lateral root meristems are likely to be the main sites of isopentenyladenosine-5′-monophosphate-dependent cytokinin synthesis, and that the aerial tissue of the plant surprisingly also was a significant source of cytokinin biosynthesis. Our demonstration of shoot-localized synthesis, together with data demonstrating that auxin imposes a very rapid regulation of cytokinin biosynthesis, illustrates that the two hormones can interact also on the metabolic level in controlling plant development, and that the aerial part of the plant has the capacity to synthesize its own cytokinin independent of long-range transport from the root system.","language":"en","number":"21","urldate":"2021-06-15","journal":"Proceedings of the National Academy of Sciences","author":[{"propositions":[],"lastnames":["Nordström"],"firstnames":["Anders"],"suffixes":[]},{"propositions":[],"lastnames":["Tarkowski"],"firstnames":["Petr"],"suffixes":[]},{"propositions":[],"lastnames":["Tarkowska"],"firstnames":["Danuse"],"suffixes":[]},{"propositions":[],"lastnames":["Norbaek"],"firstnames":["Rikke"],"suffixes":[]},{"propositions":[],"lastnames":["Åstot"],"firstnames":["Crister"],"suffixes":[]},{"propositions":[],"lastnames":["Dolezal"],"firstnames":["Karel"],"suffixes":[]},{"propositions":[],"lastnames":["Sandberg"],"firstnames":["Göran"],"suffixes":[]}],"month":"May","year":"2004","pmid":"15146070","note":"Publisher: National Academy of Sciences Section: Biological Sciences","pages":"8039–8044","bibtex":"@article{nordstrom_auxin_2004,\n\ttitle = {Auxin regulation of cytokinin biosynthesis in {Arabidopsis} thaliana: {A} factor of potential importance for auxin–cytokinin-regulated development},\n\tvolume = {101},\n\tcopyright = {Copyright © 2004, The National Academy of Sciences},\n\tissn = {0027-8424, 1091-6490},\n\tshorttitle = {Auxin regulation of cytokinin biosynthesis in {Arabidopsis} thaliana},\n\turl = {https://www.pnas.org/content/101/21/8039},\n\tdoi = {10/c2tzk7},\n\tabstract = {One of the most long-lived models in plant science is the belief that the long-distance transport and ratio of two plant hormones, auxin and cytokinin, at the site of action control major developmental events such as apical dominance. We have used in vivo deuterium labeling and mass spectrometry to investigate the dynamics of homeostatic cross talk between the two plant hormones. Interestingly, auxin mediates a very rapid negative control of the cytokinin pool by mainly suppressing the biosynthesis via the isopentenyladenosine-5′-monophosphate-independent pathway. In contrast, the effect of cytokinin overproduction on the entire auxin pool in the plant was slower, indicating that this most likely is mediated through altered development. In addition, we were able to confirm that the lateral root meristems are likely to be the main sites of isopentenyladenosine-5′-monophosphate-dependent cytokinin synthesis, and that the aerial tissue of the plant surprisingly also was a significant source of cytokinin biosynthesis. Our demonstration of shoot-localized synthesis, together with data demonstrating that auxin imposes a very rapid regulation of cytokinin biosynthesis, illustrates that the two hormones can interact also on the metabolic level in controlling plant development, and that the aerial part of the plant has the capacity to synthesize its own cytokinin independent of long-range transport from the root system.},\n\tlanguage = {en},\n\tnumber = {21},\n\turldate = {2021-06-15},\n\tjournal = {Proceedings of the National Academy of Sciences},\n\tauthor = {Nordström, Anders and Tarkowski, Petr and Tarkowska, Danuse and Norbaek, Rikke and Åstot, Crister and Dolezal, Karel and Sandberg, Göran},\n\tmonth = may,\n\tyear = {2004},\n\tpmid = {15146070},\n\tnote = {Publisher: National Academy of Sciences\nSection: Biological Sciences},\n\tpages = {8039--8044},\n}\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n","author_short":["Nordström, A.","Tarkowski, P.","Tarkowska, D.","Norbaek, R.","Åstot, C.","Dolezal, K.","Sandberg, G."],"key":"nordstrom_auxin_2004","id":"nordstrom_auxin_2004","bibbaseid":"nordstrm-tarkowski-tarkowska-norbaek-stot-dolezal-sandberg-auxinregulationofcytokininbiosynthesisinarabidopsisthalianaafactorofpotentialimportanceforauxincytokininregulateddevelopment-2004","role":"author","urls":{"Paper":"https://www.pnas.org/content/101/21/8039"},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/zotero/upscpub","dataSources":["9cGcv2t8pRzC92kzs","fvfkWcShg3Mybjoog","Tu3jPdZyJF3j547xT","3zTPPmKj8BiTcpc6C"],"keywords":[],"search_terms":["auxin","regulation","cytokinin","biosynthesis","arabidopsis","thaliana","factor","potential","importance","auxin","cytokinin","regulated","development","nordström","tarkowski","tarkowska","norbaek","åstot","dolezal","sandberg"],"title":"Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: A factor of potential importance for auxin–cytokinin-regulated development","year":2004}