GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI. Northoff, G., Walter, M., Schulte, R. F, Beck, J., Dydak, U., Henning, A., Boeker, H., Grimm, S., & Boesiger, P. Nature Neuroscience, 10(12):1515--1517, December, 2007. ![GABA concentrations in the human anterior cingulate cortex predict negative BOLD responses in fMRI [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex The human anterior cingulate cortex (ACC) is part of the default-mode network that shows predominant negative blood oxygen level-dependent (BOLD) responses in functional magnetic resonance imaging (fMRI). We combined fMRI during emotional processing and resting-state magnetic resonance spectroscopy measurements and observed that the concentration of GABA in the ACC specifically correlated with the amount of negative BOLD responses in the very same region. Our findings show that default-mode network negative BOLD responses during emotions are mediated by GABA.
@article{northoff_gaba_2007,
title = {{GABA} concentrations in the human anterior cingulate cortex predict negative {BOLD} responses in {fMRI}},
volume = {10},
issn = {1097-6256},
url = {http://www.ncbi.nlm.nih.gov/pubmed/17982452},
doi = {10.1038/nn2001},
abstract = {The human anterior cingulate cortex (ACC) is part of the default-mode network that shows predominant negative blood oxygen level-dependent (BOLD) responses in functional magnetic resonance imaging (fMRI). We combined fMRI during emotional processing and resting-state magnetic resonance spectroscopy measurements and observed that the concentration of GABA in the ACC specifically correlated with the amount of negative BOLD responses in the very same region. Our findings show that default-mode network negative BOLD responses during emotions are mediated by GABA.},
number = {12},
urldate = {2010-11-21},
journal = {Nature Neuroscience},
author = {Northoff, Georg and Walter, Martin and Schulte, Rolf F and Beck, Johannes and Dydak, Ulrike and Henning, Anke and Boeker, Heinz and Grimm, Simone and Boesiger, Peter},
month = dec,
year = {2007},
pmid = {17982452},
keywords = {GABA},
pages = {1515--1517},
file = {GABA concentrations in the human anterior cingulat... [Nat Neurosci. 2007] - PubMed result:/Users/nickb/Zotero/storage/EXFDVXD6/17982452.html:text/html;northoff2007.pdf:/Users/nickb/Zotero/storage/4K8P82FR/northoff2007.pdf:application/pdf}
}
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