Finite element modeling of gastrointestinal tissue stapling. Nováček, V., Trần, T., N., Bronson, D., Diederich, J., Godek, M., Klinge, U., Miesse, A., Staat, M., & Tolba, R. In TERMIS-AP 2011, Proceedings of the annual meeting of the Asia Pacific Chapter of the Tissue Engineering and Regenerative Medicine International Society, Singapore, August 3-5, 2011, 2011. ![Finite element modeling of gastrointestinal tissue stapling [link]](https://bibbase.org/img/filetypes/link.svg "link")
Website abstract bibtex Background Following surgical intervention, establishing GI tract continuity remains challenging due to limited knowledge regarding device effects on tissue. Significant effort has been directed toward creating reliable tissue apposition via mechanical devices, i.e., staplers. These instruments have a lengthy history of clinical use even though their impact on tissue response and healing remain unclear. This study investigates tissue response to several stapling modalities which may influence tissue regeneration and healing. Methods We developed finite element models (FEM) utilizing circular staplers often employed in GI tissue to investigate the influence of the number of staple rows (one, two, three) wire size, closed height and tissue thickness on stress within the tissues. Results For equivalent closed staple height and initial tissue thickness, each additional outer row increased the compressive stress within the tissues in the inner row(s). Smaller staple wire resulted in lower tissue stress compared to larger wire. Conclusion FEM demonstrated differences between stapling modalities tested; staple row number and wire gauge were significant factors contributing to tissue stress; in turn these factors may affect healing in a clinical setting. Additional studies will investigate possible correlates between FEM and clinically relevant in vivo studies to further validate the models.
@inproceedings{
title = {Finite element modeling of gastrointestinal tissue stapling},
type = {inproceedings},
year = {2011},
websites = {http://profiles.wizfolio.com/Termis2011/publications/19010/135984/},
id = {6e0c0de1-dc51-3eea-a97f-94d0712c79c2},
created = {2014-06-02T20:07:49.000Z},
file_attached = {false},
profile_id = {93ec0d5b-403c-3f87-b702-40b6362f05e6},
last_modified = {2017-03-14T23:34:32.861Z},
read = {false},
starred = {false},
authored = {true},
confirmed = {true},
hidden = {false},
citation_key = {novavcek2011finite},
source_type = {inproceedings},
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abstract = {Background Following surgical intervention, establishing GI tract continuity remains challenging due to limited knowledge regarding device effects on tissue. Significant effort has been directed toward creating reliable tissue apposition via mechanical devices, i.e., staplers. These instruments have a lengthy history of clinical use even though their impact on tissue response and healing remain unclear. This study investigates tissue response to several stapling modalities which may influence tissue regeneration and healing. Methods We developed finite element models (FEM) utilizing circular staplers often employed in GI tissue to investigate the influence of the number of staple rows (one, two, three) wire size, closed height and tissue thickness on stress within the tissues. Results For equivalent closed staple height and initial tissue thickness, each additional outer row increased the compressive stress within the tissues in the inner row(s). Smaller staple wire resulted in lower tissue stress compared to larger wire. Conclusion FEM demonstrated differences between stapling modalities tested; staple row number and wire gauge were significant factors contributing to tissue stress; in turn these factors may affect healing in a clinical setting. Additional studies will investigate possible correlates between FEM and clinically relevant in vivo studies to further validate the models.},
bibtype = {inproceedings},
author = {Nováček, Vit and Trần, T N and Bronson, D and Diederich, J and Godek, M and Klinge, Uwe and Miesse, A and Staat, Manfred and Tolba, R},
booktitle = {TERMIS-AP 2011, Proceedings of the annual meeting of the Asia Pacific Chapter of the Tissue Engineering and Regenerative Medicine International Society, Singapore, August 3-5, 2011}
}
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Significant effort has been directed toward creating reliable tissue apposition via mechanical devices, i.e., staplers. These instruments have a lengthy history of clinical use even though their impact on tissue response and healing remain unclear. This study investigates tissue response to several stapling modalities which may influence tissue regeneration and healing. Methods We developed finite element models (FEM) utilizing circular staplers often employed in GI tissue to investigate the influence of the number of staple rows (one, two, three) wire size, closed height and tissue thickness on stress within the tissues. Results For equivalent closed staple height and initial tissue thickness, each additional outer row increased the compressive stress within the tissues in the inner row(s). Smaller staple wire resulted in lower tissue stress compared to larger wire. Conclusion FEM demonstrated differences between stapling modalities tested; staple row number and wire gauge were significant factors contributing to tissue stress; in turn these factors may affect healing in a clinical setting. 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Significant effort has been directed toward creating reliable tissue apposition via mechanical devices, i.e., staplers. These instruments have a lengthy history of clinical use even though their impact on tissue response and healing remain unclear. This study investigates tissue response to several stapling modalities which may influence tissue regeneration and healing. Methods We developed finite element models (FEM) utilizing circular staplers often employed in GI tissue to investigate the influence of the number of staple rows (one, two, three) wire size, closed height and tissue thickness on stress within the tissues. Results For equivalent closed staple height and initial tissue thickness, each additional outer row increased the compressive stress within the tissues in the inner row(s). Smaller staple wire resulted in lower tissue stress compared to larger wire. 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