High unreported mortality in children and youth (\textless25 years) living with HIV who were lost to care from antiretroviral therapy programs in southern Africa: results from a multicountry tracing study. Nyakato, P., Christ, B., Anderegg, N., Muhairwe, J., Jefferys, L., van Dijk, J., Vinikoor, M. J, van Lettow, M., Chimbetete, C., Phiri, S. J, Egger, M., Ballif, M., Yiannoutsos, C. T, Schomaker, M., Kassanjee, R., Davies, M., & Cornell, M. JAIDS, 91(5):429–433, Ovid Technologies (Wolters Kluwer Health), dec, 2022.
High unreported mortality in children and youth (\textless25 years) living with HIV who were lost to care from antiretroviral therapy programs in southern Africa: results from a multicountry tracing study [link]Paper  doi  abstract   bibtex   
BACKGROUND: Antiretroviral therapy (ART) program mortality maybe underestimated if deceased patients are misclassified as lost. METHODS: We used two-stage inverse probability weighting to account for probability of being: sampled for tracing and found by the tracer. RESULTS: Among 680 children and youth aged \textless25 years on ART who were lost and traced in Southern Africa between October 2017-November 2019, estimated mortality was high at 9.1% (62/680). After adjusting for measured covariates and within-site clustering, mortality remained lower for young adults aged 20-24 years compared to infants aged \textless2years (adjusted Hazard ratio (aHR): 0.40 (95% confidence interval (CI): 0.31, 0.51)). CONCLUSIONS: Our study confirms high unreported mortality in children and youth who are lost and the need for tracing to assess vital status among those who are lost to accurately report on program mortality.
@article{Nyakato2022,
abstract = {BACKGROUND: Antiretroviral therapy (ART) program mortality maybe underestimated if deceased patients are misclassified as lost. METHODS: We used two-stage inverse probability weighting to account for probability of being: sampled for tracing and found by the tracer. RESULTS: Among 680 children and youth aged {\textless}25 years on ART who were lost and traced in Southern Africa between October 2017-November 2019, estimated mortality was high at 9.1{\%} (62/680). After adjusting for measured covariates and within-site clustering, mortality remained lower for young adults aged 20-24 years compared to infants aged {\textless}2years (adjusted Hazard ratio (aHR): 0.40 (95{\%} confidence interval (CI): 0.31, 0.51)). CONCLUSIONS: Our study confirms high unreported mortality in children and youth who are lost and the need for tracing to assess vital status among those who are lost to accurately report on program mortality.},
author = {Nyakato, Patience and Christ, Benedikt and Anderegg, Nanina and Muhairwe, Josephine and Jefferys, Laura and van Dijk, Janneke and Vinikoor, Michael J and van Lettow, Monique and Chimbetete, Cleophas and Phiri, Sam J and Egger, Matthias and Ballif, Marie and Yiannoutsos, Constantin T and Schomaker, Michael and Kassanjee, Reshma and Davies, Mary-Ann and Cornell, Morna},
doi = {10.1097/QAI.0000000000003090},
file = {:C$\backslash$:/Users/01462563/AppData/Local/Mendeley Ltd./Mendeley Desktop/Downloaded/Nyakato et al. - 2022 - High unreported mortality in children and youth (25 years) living with HIV who were lost to care from antiretrov.pdf:pdf},
issn = {1525-4135},
journal = {JAIDS},
keywords = {OA{\_}PMC,OA{\_}repository,fund{\_}ack,original},
mendeley-tags = {OA{\_}PMC,OA{\_}repository,fund{\_}ack,original},
month = {dec},
number = {5},
pages = {429--433},
pmid = {36099024},
publisher = {Ovid Technologies (Wolters Kluwer Health)},
title = {{High unreported mortality in children and youth ({\textless}25 years) living with HIV who were lost to care from antiretroviral therapy programs in southern Africa: results from a multicountry tracing study}},
url = {https://journals.lww.com/jaids/Fulltext/2022/12150/High{\_}Unreported{\_}Mortality{\_}in{\_}Children{\_}and{\_}Youth.2.aspx https://boris.unibe.ch/172865/1/High{\_}unreported{\_}mortality{\_}in{\_}children{\_}and{\_}youth.108.pdf https://pubmed.ncbi.nlm.nih.gov/36099024/},
volume = {91},
year = {2022}
}

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