Classification of DLC films in terms of biological response. Ohgoe, Y., Hirakuri, K. K., Saitoh, H., Nakahigashi, T., Ohtake, N., Hirata, A., Kanda, K., Hiratsuka, M., & Fukui, Y. SURFACE & COATINGS TECHNOLOGY, 207:350-354, AUG 25, 2012. doi abstract bibtex In this study, various kinds of diamond-like carbon (DLC) films were classified in terms of their biological responses (specifically the number of adhering cells). Forty three kinds of DLC samples that had been deposited on Si substrate by various physical vapor deposition (PVD) and chemical vapor deposition (CVD) system equipment were obtained at random from coating companies, universities, and public organizations in Japan. Mouth fibroblasts (NIH-3T3) were used to estimate the cellular responses on the DLC samples. During the cell culture, 12 of the DLC samples were peeled off from the Si substrates. As a result, the remaining 31 DLC samples with a wide range of properties were classified into four groups in terms of their number of adhering cells. Group 1 (high density, low sp(2) content, and low hydrogen contents) and Group 2 (low or medium density, high sp(2) content, and low hydrogen contents) had a low number of adhering cells. Group 3 (medium density, and medium sp(2) content, and relatively high hydrogen contents) and Group 4 (low sp(2) content, low density, and a wide range of hydrogen contents) had a wide range of number of adhering cells. Especially, 7 DLC samples in Group 4 had good cell growth. It was shown that this classification is one of the design criteria of DLC film deposition for biomaterials regardless of the various deposition system equipment. It is expected that ordinary DLC users can carefully select a DLC film for specific applications to medical devices using the classification. (C) 2012 Elsevier B.V. All rights reserved.
@article{ ISI:000309501600050,
Author = {Ohgoe, Yasuharu and Hirakuri, Kenji K. and Saitoh, Hidetoshi and
Nakahigashi, Takahiro and Ohtake, Naoto and Hirata, Atsushi and Kanda,
Kazuhiro and Hiratsuka, Masanori and Fukui, Yasuhiro},
Title = {{Classification of DLC films in terms of biological response}},
Journal = {{SURFACE \& COATINGS TECHNOLOGY}},
Year = {{2012}},
Volume = {{207}},
Pages = {{350-354}},
Month = {{AUG 25}},
Abstract = {{In this study, various kinds of diamond-like carbon (DLC) films were
classified in terms of their biological responses (specifically the
number of adhering cells). Forty three kinds of DLC samples that had
been deposited on Si substrate by various physical vapor deposition
(PVD) and chemical vapor deposition (CVD) system equipment were obtained
at random from coating companies, universities, and public organizations
in Japan. Mouth fibroblasts (NIH-3T3) were used to estimate the cellular
responses on the DLC samples. During the cell culture, 12 of the DLC
samples were peeled off from the Si substrates. As a result, the
remaining 31 DLC samples with a wide range of properties were classified
into four groups in terms of their number of adhering cells. Group 1
(high density, low sp(2) content, and low hydrogen contents) and Group 2
(low or medium density, high sp(2) content, and low hydrogen contents)
had a low number of adhering cells. Group 3 (medium density, and medium
sp(2) content, and relatively high hydrogen contents) and Group 4 (low
sp(2) content, low density, and a wide range of hydrogen contents) had a
wide range of number of adhering cells. Especially, 7 DLC samples in
Group 4 had good cell growth. It was shown that this classification is
one of the design criteria of DLC film deposition for biomaterials
regardless of the various deposition system equipment. It is expected
that ordinary DLC users can carefully select a DLC film for specific
applications to medical devices using the classification. (C) 2012
Elsevier B.V. All rights reserved.}},
DOI = {{10.1016/j.surfcoat.2012.07.018}},
ISSN = {{0257-8972}},
Unique-ID = {{ISI:000309501600050}},
}
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K.","Saitoh, H.","Nakahigashi, T.","Ohtake, N.","Hirata, A.","Kanda, K.","Hiratsuka, M.","Fukui, Y."],"bibdata":{"bibtype":"article","type":"article","author":[{"propositions":[],"lastnames":["Ohgoe"],"firstnames":["Yasuharu"],"suffixes":[]},{"propositions":[],"lastnames":["Hirakuri"],"firstnames":["Kenji","K."],"suffixes":[]},{"propositions":[],"lastnames":["Saitoh"],"firstnames":["Hidetoshi"],"suffixes":[]},{"propositions":[],"lastnames":["Nakahigashi"],"firstnames":["Takahiro"],"suffixes":[]},{"propositions":[],"lastnames":["Ohtake"],"firstnames":["Naoto"],"suffixes":[]},{"propositions":[],"lastnames":["Hirata"],"firstnames":["Atsushi"],"suffixes":[]},{"propositions":[],"lastnames":["Kanda"],"firstnames":["Kazuhiro"],"suffixes":[]},{"propositions":[],"lastnames":["Hiratsuka"],"firstnames":["Masanori"],"suffixes":[]},{"propositions":[],"lastnames":["Fukui"],"firstnames":["Yasuhiro"],"suffixes":[]}],"title":"Classification of DLC films in terms of biological response","journal":"SURFACE & COATINGS TECHNOLOGY","year":"2012","volume":"207","pages":"350-354","month":"AUG 25","abstract":"In this study, various kinds of diamond-like carbon (DLC) films were classified in terms of their biological responses (specifically the number of adhering cells). Forty three kinds of DLC samples that had been deposited on Si substrate by various physical vapor deposition (PVD) and chemical vapor deposition (CVD) system equipment were obtained at random from coating companies, universities, and public organizations in Japan. Mouth fibroblasts (NIH-3T3) were used to estimate the cellular responses on the DLC samples. During the cell culture, 12 of the DLC samples were peeled off from the Si substrates. As a result, the remaining 31 DLC samples with a wide range of properties were classified into four groups in terms of their number of adhering cells. Group 1 (high density, low sp(2) content, and low hydrogen contents) and Group 2 (low or medium density, high sp(2) content, and low hydrogen contents) had a low number of adhering cells. Group 3 (medium density, and medium sp(2) content, and relatively high hydrogen contents) and Group 4 (low sp(2) content, low density, and a wide range of hydrogen contents) had a wide range of number of adhering cells. Especially, 7 DLC samples in Group 4 had good cell growth. It was shown that this classification is one of the design criteria of DLC film deposition for biomaterials regardless of the various deposition system equipment. It is expected that ordinary DLC users can carefully select a DLC film for specific applications to medical devices using the classification. (C) 2012 Elsevier B.V. All rights reserved.","doi":"10.1016/j.surfcoat.2012.07.018","issn":"0257-8972","unique-id":"ISI:000309501600050","bibtex":"@article{ ISI:000309501600050,\nAuthor = {Ohgoe, Yasuharu and Hirakuri, Kenji K. and Saitoh, Hidetoshi and\n Nakahigashi, Takahiro and Ohtake, Naoto and Hirata, Atsushi and Kanda,\n Kazuhiro and Hiratsuka, Masanori and Fukui, Yasuhiro},\nTitle = {{Classification of DLC films in terms of biological response}},\nJournal = {{SURFACE \\& COATINGS TECHNOLOGY}},\nYear = {{2012}},\nVolume = {{207}},\nPages = {{350-354}},\nMonth = {{AUG 25}},\nAbstract = {{In this study, various kinds of diamond-like carbon (DLC) films were\n classified in terms of their biological responses (specifically the\n number of adhering cells). Forty three kinds of DLC samples that had\n been deposited on Si substrate by various physical vapor deposition\n (PVD) and chemical vapor deposition (CVD) system equipment were obtained\n at random from coating companies, universities, and public organizations\n in Japan. Mouth fibroblasts (NIH-3T3) were used to estimate the cellular\n responses on the DLC samples. During the cell culture, 12 of the DLC\n samples were peeled off from the Si substrates. As a result, the\n remaining 31 DLC samples with a wide range of properties were classified\n into four groups in terms of their number of adhering cells. Group 1\n (high density, low sp(2) content, and low hydrogen contents) and Group 2\n (low or medium density, high sp(2) content, and low hydrogen contents)\n had a low number of adhering cells. Group 3 (medium density, and medium\n sp(2) content, and relatively high hydrogen contents) and Group 4 (low\n sp(2) content, low density, and a wide range of hydrogen contents) had a\n wide range of number of adhering cells. Especially, 7 DLC samples in\n Group 4 had good cell growth. It was shown that this classification is\n one of the design criteria of DLC film deposition for biomaterials\n regardless of the various deposition system equipment. It is expected\n that ordinary DLC users can carefully select a DLC film for specific\n applications to medical devices using the classification. (C) 2012\n Elsevier B.V. All rights reserved.}},\nDOI = {{10.1016/j.surfcoat.2012.07.018}},\nISSN = {{0257-8972}},\nUnique-ID = {{ISI:000309501600050}},\n}\n\n","author_short":["Ohgoe, Y.","Hirakuri, K. 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