Spontaneous Regression of Hepatocellular Carcinoma: Its Imaging Course Leading to Complete Disappearance. Okano, A. & Ohana, M. Case Reports in Oncology, 8(1):94–100, 2015.
Spontaneous Regression of Hepatocellular Carcinoma: Its Imaging Course Leading to Complete Disappearance [link]Paper  doi  abstract   bibtex   
Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We followed a detailed clinical course of a spontaneous and complete disappearance of HCC during a short interval. A 73-year-old man with hepatitis B virus infection presented with a 15-mm mass in the right anterior superior segment of the liver. The mass was diagnosed as HCC by imaging findings. We found an elevated serum α-fetoprotein (AFP) level of 748 ng/ml. The tumor regressed to 6 mm on imaging examination, and the AFP serum level decreased to 87.8 ng/ml 1 month after the diagnostic hepatic angiography. Therefore, the patient was followed up without any treatment for HCC. The tumor disappeared 5 months later when the AFP serum level was 5.0 ng/ml. The diagnostic hepatic angiography might have had some effect on the spontaneous regression of HCC in the present case.
@article{okano_spontaneous_2015,
	title = {Spontaneous {Regression} of {Hepatocellular} {Carcinoma}: {Its} {Imaging} {Course} {Leading} to {Complete} {Disappearance}},
	volume = {8},
	issn = {1662-6575},
	shorttitle = {Spontaneous {Regression} of {Hepatocellular} {Carcinoma}},
	url = {https://www.karger.com/Article/FullText/375486},
	doi = {10.1159/000375486},
	abstract = {Spontaneous regression of hepatocellular carcinoma (HCC) is a rare phenomenon. We followed a detailed clinical course of a spontaneous and complete disappearance of HCC during a short interval. A 73-year-old man with hepatitis B virus infection presented with a 15-mm mass in the right anterior superior segment of the liver. The mass was diagnosed as HCC by imaging findings. We found an elevated serum α-fetoprotein (AFP) level of 748 ng/ml. The tumor regressed to 6 mm on imaging examination, and the AFP serum level decreased to 87.8 ng/ml 1 month after the diagnostic hepatic angiography. Therefore, the patient was followed up without any treatment for HCC. The tumor disappeared 5 months later when the AFP serum level was 5.0 ng/ml. The diagnostic hepatic angiography might have had some effect on the spontaneous regression of HCC in the present case.},
	language = {english},
	number = {1},
	urldate = {2018-07-07},
	journal = {Case Reports in Oncology},
	author = {Okano, Akihiro and Ohana, Masaya},
	year = {2015},
	pmid = {25848359},
	pages = {94--100},
}

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