@Article{RSM:Oki95,
  author =       "P.M. Okin and P. Kligfield",
  title =        "Heart rate adjustment of {ST} segment depression and
                 performance of the exercise electrocardiogram: a
                 critical evaluation.",
  journal =      j-ACC,
  year =         "1995",
  month =        jun,
  volume =       "25",
  number =       "7",
  pages =        "1726--1735",
  robnote =      "Analysis of the rate-related change in
                 exercise-induced ST segment depression using the
                 exercise ST segment/heart rate slope and ST
                 segment/heart rate index can improve the accuracy of
                 the exercise electrocardiogram (ECG) for the
                 identification of patients with coronary artery
                 disease, recognition of patients with anatomically or
                 functionally severe coronary obstruction and detection
                 of patients at increased risk for future coronary
                 events. These methods provide a more physiologic
                 approach to analysis of the ST segment response to
                 exercise by adjusting the apparent severity of ischemia
                 for the corresponding increase in myocardial oxygen
                 demand, which in turn can be linearly related to
                 increasing heart rate. Solid-angle theory provides a
                 model for the linear relation of ST segment depression
                 to heart rate during exercise and a framework for
                 understanding the relation of the ST segment/heart rate
                 slope to the presence and extent of coronary artery
                 disease. False positive and false negative test results
                 of the heart rate-adjusted methods are well known in
                 selected populations and require further clarification.
                 Application of these methods is also highly dependent
                 on the type of exercise protocol, number of ECG leads
                 examined, timing of ST segment measurement relative to
                 the J point and accuracy and precision of ST segment
                 measurement. These methodologic details have been an
                 important limitation to test application when
                 traditional protocols and measurement procedures are
                 required. When applied with attention to required
                 details, the heart rate-adjusted methods can improve
                 the usefulness of the exercise ECG in a range of
                 clinically relevant populations.",
  bibdate =      "Thu Sep 20 12:27:47 2001",
}

{"_id":"wGhpgehtvftEYr9eX","bibbaseid":"okin-kligfield-heartrateadjustmentofstsegmentdepressionandperformanceoftheexerciseelectrocardiogramacriticalevaluation-1995","downloads":0,"creationDate":"2016-07-01T21:38:38.438Z","title":"Heart rate adjustment of ST segment depression and performance of the exercise electrocardiogram: a critical evaluation.","author_short":["Okin, P.","Kligfield, P."],"year":1995,"bibtype":"article","biburl":"http://www.sci.utah.edu/~macleod/Bibtex/biglit.bib","bibdata":{"bibtype":"article","type":"article","author":[{"firstnames":["P.M."],"propositions":[],"lastnames":["Okin"],"suffixes":[]},{"firstnames":["P."],"propositions":[],"lastnames":["Kligfield"],"suffixes":[]}],"title":"Heart rate adjustment of ST segment depression and performance of the exercise electrocardiogram: a critical evaluation.","journal":"j-ACC","year":"1995","month":"June","volume":"25","number":"7","pages":"1726–1735","robnote":"Analysis of the rate-related change in exercise-induced ST segment depression using the exercise ST segment/heart rate slope and ST segment/heart rate index can improve the accuracy of the exercise electrocardiogram (ECG) for the identification of patients with coronary artery disease, recognition of patients with anatomically or functionally severe coronary obstruction and detection of patients at increased risk for future coronary events. These methods provide a more physiologic approach to analysis of the ST segment response to exercise by adjusting the apparent severity of ischemia for the corresponding increase in myocardial oxygen demand, which in turn can be linearly related to increasing heart rate. Solid-angle theory provides a model for the linear relation of ST segment depression to heart rate during exercise and a framework for understanding the relation of the ST segment/heart rate slope to the presence and extent of coronary artery disease. False positive and false negative test results of the heart rate-adjusted methods are well known in selected populations and require further clarification. Application of these methods is also highly dependent on the type of exercise protocol, number of ECG leads examined, timing of ST segment measurement relative to the J point and accuracy and precision of ST segment measurement. These methodologic details have been an important limitation to test application when traditional protocols and measurement procedures are required. When applied with attention to required details, the heart rate-adjusted methods can improve the usefulness of the exercise ECG in a range of clinically relevant populations.","bibdate":"Thu Sep 20 12:27:47 2001","bibtex":"@Article{RSM:Oki95,\n author = \"P.M. Okin and P. Kligfield\",\n title = \"Heart rate adjustment of {ST} segment depression and\n performance of the exercise electrocardiogram: a\n critical evaluation.\",\n journal = j-ACC,\n year = \"1995\",\n month = jun,\n volume = \"25\",\n number = \"7\",\n pages = \"1726--1735\",\n robnote = \"Analysis of the rate-related change in\n exercise-induced ST segment depression using the\n exercise ST segment/heart rate slope and ST\n segment/heart rate index can improve the accuracy of\n the exercise electrocardiogram (ECG) for the\n identification of patients with coronary artery\n disease, recognition of patients with anatomically or\n functionally severe coronary obstruction and detection\n of patients at increased risk for future coronary\n events. These methods provide a more physiologic\n approach to analysis of the ST segment response to\n exercise by adjusting the apparent severity of ischemia\n for the corresponding increase in myocardial oxygen\n demand, which in turn can be linearly related to\n increasing heart rate. Solid-angle theory provides a\n model for the linear relation of ST segment depression\n to heart rate during exercise and a framework for\n understanding the relation of the ST segment/heart rate\n slope to the presence and extent of coronary artery\n disease. False positive and false negative test results\n of the heart rate-adjusted methods are well known in\n selected populations and require further clarification.\n Application of these methods is also highly dependent\n on the type of exercise protocol, number of ECG leads\n examined, timing of ST segment measurement relative to\n the J point and accuracy and precision of ST segment\n measurement. These methodologic details have been an\n important limitation to test application when\n traditional protocols and measurement procedures are\n required. When applied with attention to required\n details, the heart rate-adjusted methods can improve\n the usefulness of the exercise ECG in a range of\n clinically relevant populations.\",\n bibdate = \"Thu Sep 20 12:27:47 2001\",\n}\n\n","author_short":["Okin, P.","Kligfield, P."],"key":"RSM:Oki95","id":"RSM:Oki95","bibbaseid":"okin-kligfield-heartrateadjustmentofstsegmentdepressionandperformanceoftheexerciseelectrocardiogramacriticalevaluation-1995","role":"author","urls":{},"metadata":{"authorlinks":{}},"downloads":0,"html":""},"search_terms":["heart","rate","adjustment","segment","depression","performance","exercise","electrocardiogram","critical","evaluation","okin","kligfield"],"keywords":[],"authorIDs":[],"dataSources":["5HG3Kp8zRwDd7FotB"]}