A systematic review of the label accuracy of cannabinoid-based products in regulated markets: is what’s on the label what’s in the product?. Oldfield, K., Ryan, J., Doppen, M., Kung, S., Braithwaite, I., & Newton-Howes, G. Australasian Psychiatry, 29(1):88–96, February, 2021.
A systematic review of the label accuracy of cannabinoid-based products in regulated markets: is what’s on the label what’s in the product? [link]Paper  doi  abstract   bibtex   1 download  
Objectives: To review the literature regarding label accuracy and contamination of medical cannabinoid-based products. Methods: A systematic review with meta-analysis following PRISMA guidelines. This study is registered with PROSPERO (CRD42019131565). Results: Five studies reported label accuracy data ranging between 17% and 86%. Four studies reported contaminants, including pesticides, solvents and AB-FUBINACA. Meta-analysis was limited to the proportion of pesticide-contaminated samples found in two studies (0.25 (95% CI [0.10, 0.40])) and displayed significant heterogeneity. Conclusions: Label inaccuracies and contaminants are found across a spectrum of cannabinoid-based products. The review highlights the paucity and heterogeneity of research relating to cannabinoid-based products in light of changing global legislation. Further robust research is required to support ongoing pharmacovigilance and patient safety.
@article{oldfield_systematic_2021,
	title = {A systematic review of the label accuracy of cannabinoid-based products in regulated markets: is what’s on the label what’s in the product?},
	volume = {29},
	issn = {1039-8562, 1440-1665},
	shorttitle = {A systematic review of the label accuracy of cannabinoid-based products in regulated markets},
	url = {http://journals.sagepub.com/doi/10.1177/1039856220965334},
	doi = {10.1177/1039856220965334},
	abstract = {Objectives:
              To review the literature regarding label accuracy and contamination of medical cannabinoid-based products.
            
            
              Methods:
              A systematic review with meta-analysis following PRISMA guidelines. This study is registered with PROSPERO (CRD42019131565).
            
            
              Results:
              Five studies reported label accuracy data ranging between 17\% and 86\%. Four studies reported contaminants, including pesticides, solvents and AB-FUBINACA. Meta-analysis was limited to the proportion of pesticide-contaminated samples found in two studies (0.25 (95\% CI [0.10, 0.40])) and displayed significant heterogeneity.
            
            
              Conclusions:
              Label inaccuracies and contaminants are found across a spectrum of cannabinoid-based products. The review highlights the paucity and heterogeneity of research relating to cannabinoid-based products in light of changing global legislation. Further robust research is required to support ongoing pharmacovigilance and patient safety.},
	language = {en},
	number = {1},
	urldate = {2021-04-30},
	journal = {Australasian Psychiatry},
	author = {Oldfield, Karen and Ryan, John and Doppen, Marjan and Kung, Stacey and Braithwaite, Irene and Newton-Howes, Giles},
	month = feb,
	year = {2021},
	pages = {88--96},
}

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