@ARTICLE{Owens2000-nl,
  title    = "Calcium dynamics of neocortical ventricular zone cells",
  author   = "Owens, D F and Flint, A C and Dammerman, R S and Kriegstein, A R",
  abstract = "Cell-cell signaling within the neocortical ventricular zone (VZ)
              has been shown to influence the proliferation of VZ precursor
              cells and the subsequent differentiation and fate of postmitotic
              neurons. Calcium (Ca(2+)), a ubiquitous second messenger
              implicated in the regulation of many aspects of development, may
              play a role in these signaling events. Accordingly, we have
              examined the spatiotemporal patterns of spontaneous intracellular
              free Ca(2+) ([Ca(2+)](i)) fluctuations of cells within the intact
              neocortical VZ. Previous observations have demonstrated that
              similar patterns of spontaneous [Ca(2+)](i) increase occur in
              both proliferative and postmitotic cortical cells, suggesting
              that they may be mechanistically similar. Our results suggest
              that the changes in [Ca(2+)](i) in VZ cells and cortical plate
              neurons are likely triggered by different mechansims, and imply
              that similar changes in [Ca(2+)](i) may underlie different
              signaling events during distinct phases of neocortical
              development.",
  journal  = "Dev Neurosci",
  volume   =  22,
  number   = "1-2",
  pages    = "25--33",
  year     =  2000,
  address  = "Switzerland",
  language = "en"
}

{"_id":"bFPf3wwAaFtEd6aJY","bibbaseid":"owens-flint-dammerman-kriegstein-calciumdynamicsofneocorticalventricularzonecells-2000","author_short":["Owens, D F","Flint, A C","Dammerman, R S","Kriegstein, A R"],"bibdata":{"bibtype":"article","type":"article","title":"Calcium dynamics of neocortical ventricular zone cells","author":[{"propositions":[],"lastnames":["Owens"],"firstnames":["D","F"],"suffixes":[]},{"propositions":[],"lastnames":["Flint"],"firstnames":["A","C"],"suffixes":[]},{"propositions":[],"lastnames":["Dammerman"],"firstnames":["R","S"],"suffixes":[]},{"propositions":[],"lastnames":["Kriegstein"],"firstnames":["A","R"],"suffixes":[]}],"abstract":"Cell-cell signaling within the neocortical ventricular zone (VZ) has been shown to influence the proliferation of VZ precursor cells and the subsequent differentiation and fate of postmitotic neurons. Calcium (Ca(2+)), a ubiquitous second messenger implicated in the regulation of many aspects of development, may play a role in these signaling events. Accordingly, we have examined the spatiotemporal patterns of spontaneous intracellular free Ca(2+) ([Ca(2+)](i)) fluctuations of cells within the intact neocortical VZ. Previous observations have demonstrated that similar patterns of spontaneous [Ca(2+)](i) increase occur in both proliferative and postmitotic cortical cells, suggesting that they may be mechanistically similar. Our results suggest that the changes in [Ca(2+)](i) in VZ cells and cortical plate neurons are likely triggered by different mechansims, and imply that similar changes in [Ca(2+)](i) may underlie different signaling events during distinct phases of neocortical development.","journal":"Dev Neurosci","volume":"22","number":"1-2","pages":"25–33","year":"2000","address":"Switzerland","language":"en","bibtex":"@ARTICLE{Owens2000-nl,\n title = \"Calcium dynamics of neocortical ventricular zone cells\",\n author = \"Owens, D F and Flint, A C and Dammerman, R S and Kriegstein, A R\",\n abstract = \"Cell-cell signaling within the neocortical ventricular zone (VZ)\n has been shown to influence the proliferation of VZ precursor\n cells and the subsequent differentiation and fate of postmitotic\n neurons. Calcium (Ca(2+)), a ubiquitous second messenger\n implicated in the regulation of many aspects of development, may\n play a role in these signaling events. Accordingly, we have\n examined the spatiotemporal patterns of spontaneous intracellular\n free Ca(2+) ([Ca(2+)](i)) fluctuations of cells within the intact\n neocortical VZ. Previous observations have demonstrated that\n similar patterns of spontaneous [Ca(2+)](i) increase occur in\n both proliferative and postmitotic cortical cells, suggesting\n that they may be mechanistically similar. Our results suggest\n that the changes in [Ca(2+)](i) in VZ cells and cortical plate\n neurons are likely triggered by different mechansims, and imply\n that similar changes in [Ca(2+)](i) may underlie different\n signaling events during distinct phases of neocortical\n development.\",\n journal = \"Dev Neurosci\",\n volume = 22,\n number = \"1-2\",\n pages = \"25--33\",\n year = 2000,\n address = \"Switzerland\",\n language = \"en\"\n}\n\n","author_short":["Owens, D F","Flint, A C","Dammerman, R S","Kriegstein, A R"],"key":"Owens2000-nl","id":"Owens2000-nl","bibbaseid":"owens-flint-dammerman-kriegstein-calciumdynamicsofneocorticalventricularzonecells-2000","role":"author","urls":{},"metadata":{"authorlinks":{}}},"bibtype":"article","biburl":"https://bibbase.org/f/EJMp3HRuxirjxpcXh/references.bib","dataSources":["sAFYeB74DpbdXM9NN","4zx9n2tbeLTix3Wxr","k3cdWrThyTh5o59Rm","hq9pebjzmsTuyxGGx","h8Atv2SAy4PmShg5j"],"keywords":[],"search_terms":["calcium","dynamics","neocortical","ventricular","zone","cells","owens","flint","dammerman","kriegstein"],"title":"Calcium dynamics of neocortical ventricular zone cells","year":2000}