Bioinformatics, genomics and evolution of non-flagellar type-III secretion systems: a Darwinian perpective⋆. Pallen, M. J., Beatson, S. A., & Bailey, C. M. FEMS Microbiology Reviews, 29(2):201--229, 2005.
Bioinformatics, genomics and evolution of non-flagellar type-III secretion systems: a Darwinian perpective⋆ [link]Paper  doi  abstract   bibtex   
We review the biology of non-flagellar type-III secretion systems from a Darwinian perspective, highlighting the themes of evolution, conservation, variation and decay. The presence of these systems in environmental organisms such as Myxococcus, Desulfovibrio and Verrucomicrobium hints at roles beyond virulence. We review newly discovered sequence homologies (e.g., YopN/TyeA and SepL). We discuss synapomorphies that might be useful in formulating a taxonomy of type-III secretion. The problem of information overload is likely to be ameliorated by launch of a web site devoted to the comparative biology of type-III secretion (http://3base.bham.ac.uk).
@article{pallen_bioinformatics_2005,
	title = {Bioinformatics, genomics and evolution of non-flagellar type-{III} secretion systems: a {Darwinian} perpective⋆},
	volume = {29},
	issn = {1574-6976},
	shorttitle = {Bioinformatics, genomics and evolution of non-flagellar type-{III} secretion systems},
	url = {http://onlinelibrary.wiley.com/doi/10.1016/j.femsre.2005.01.001/abstract},
	doi = {10.1016/j.femsre.2005.01.001},
	abstract = {We review the biology of non-flagellar type-III secretion systems from a Darwinian perspective, highlighting the themes of evolution, conservation, variation and decay. The presence of these systems in environmental organisms such as Myxococcus, Desulfovibrio and Verrucomicrobium hints at roles beyond virulence. We review newly discovered sequence homologies (e.g., YopN/TyeA and SepL). We discuss synapomorphies that might be useful in formulating a taxonomy of type-III secretion. The problem of information overload is likely to be ameliorated by launch of a web site devoted to the comparative biology of type-III secretion (http://3base.bham.ac.uk).},
	language = {en},
	number = {2},
	urldate = {2014-12-26TZ},
	journal = {FEMS Microbiology Reviews},
	author = {Pallen, Mark J. and Beatson, Scott A. and Bailey, Christopher M.},
	year = {2005},
	keywords = {Bacterial virulence, Chaperones, Evolution, Genomics, Homology, Symbiosis, Type-III secretion, bioinformatics},
	pages = {201--229}
}

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