Small intestine contrast ultrasonography in pediatric Crohn's disease. Pallotta, N., Civitelli, F., Di Nardo, G., Vincoli, G., Aloi, M., Viola, F., Capocaccia, P., Corazziari, E., & Cucchiara, S. The Journal of Pediatrics, 163(3):778--784.e1, September, 2013.
doi  abstract   bibtex   
OBJECTIVE: To evaluate the diagnostic accuracy of small intestine contrast ultrasonography (SICUS) in pediatric Crohn's disease (CD). STUDY DESIGN: A total of 51 consecutive patients (median age 15 years; range 3-20, 31 male patients), 21 with suspected and 30 with proven CD, were studied. All patients underwent standard ultrasonography (ie, transabdominal ultrasonography [TUS]), SICUS, small bowel follow-through, and upper and lower endoscopy. SICUS was performed in patients after they ingested an oral contrast solution. TUS and SICUS were compared with small bowel follow-through and endoscopy via use of the final diagnosis as reference standard. RESULTS: In undiagnosed patients, the sensitivity and specificity of TUS and SICUS in detecting CD small bowel lesions were 75% and 100% and 100% and 100%, respectively. In patients with proven CD, the sensitivity and specificity of TUS and SICUS were 76% and 100% and 96% and 100%, respectively. The agreement (k) with radiology for site of lesions was almost perfect for SICUS (0.93), both for jejunal and ileal lesions, and it was fair (0.40) for jejunal and substantial (0.68) for ileal lesions for TUS. Compared with radiology SICUS correctly assessed the length of lesions, whereas TUS underestimated it (P = .0001). CONCLUSIONS: The radiation-free technique SICUS is comparable with radiology and more accurate than TUS in assessing small bowel lesions in pediatric CD, mainly in the detection of proximal small bowel disease.
@article{pallotta_small_2013,
	title = {Small intestine contrast ultrasonography in pediatric {Crohn}'s disease},
	volume = {163},
	issn = {1097-6833},
	doi = {10.1016/j.jpeds.2013.03.056},
	abstract = {OBJECTIVE: To evaluate the diagnostic accuracy of small intestine contrast ultrasonography (SICUS) in pediatric Crohn's disease (CD).
STUDY DESIGN: A total of 51 consecutive patients (median age 15 years; range 3-20, 31 male patients), 21 with suspected and 30 with proven CD, were studied. All patients underwent standard ultrasonography (ie, transabdominal ultrasonography [TUS]), SICUS, small bowel follow-through, and upper and lower endoscopy. SICUS was performed in patients after they ingested an oral contrast solution. TUS and SICUS were compared with small bowel follow-through and endoscopy via use of the final diagnosis as reference standard.
RESULTS: In undiagnosed patients, the sensitivity and specificity of TUS and SICUS in detecting CD small bowel lesions were 75\% and 100\% and 100\% and 100\%, respectively. In patients with proven CD, the sensitivity and specificity of TUS and SICUS were 76\% and 100\% and 96\% and 100\%, respectively. The agreement (k) with radiology for site of lesions was almost perfect for SICUS (0.93), both for jejunal and ileal lesions, and it was fair (0.40) for jejunal and substantial (0.68) for ileal lesions for TUS. Compared with radiology SICUS correctly assessed the length of lesions, whereas TUS underestimated it (P = .0001).
CONCLUSIONS: The radiation-free technique SICUS is comparable with radiology and more accurate than TUS in assessing small bowel lesions in pediatric CD, mainly in the detection of proximal small bowel disease.},
	language = {eng},
	number = {3},
	journal = {The Journal of Pediatrics},
	author = {Pallotta, Nadia and Civitelli, Fortunata and Di Nardo, Giovanni and Vincoli, Giuseppina and Aloi, Marina and Viola, Franca and Capocaccia, Paolo and Corazziari, Enrico and Cucchiara, Salvatore},
	month = sep,
	year = {2013},
	pmid = {23623514},
	keywords = {Adolescent, CD, Child, Child, Preschool, Contrast Media, Crohn disease, Crohn's disease, Endoscopy, Gastrointestinal, Female, GI, Humans, IBD, Inflammatory bowel disease, Intestine, Small, MR, Magnetic resonance, Male, Polyethylene Glycols, Prospective Studies, SBFT, SICUS, Sensitivity and Specificity, Small bowel follow-through, Small intestine contrast ultrasonography, TUS, US, Young Adult, gastrointestinal, transabdominal ultrasonography, ultrasonography},
	pages = {778--784.e1}
}

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