Variable temperature processing by plasmodesmata regulates robust bud dormancy release. Pandey, S. K., Moraes, T. S., Nair, A., Aryal, B., Azeez, A., Miskolczi, P., Maucort, G., Cordelières, F. P., Brocard, L., Davis, G. V., Dromiack, H., Khanapurkar, S., Walker, S. I., Bassel, G. W., Bayer, E. M., & Bhalerao, R. P. Nature Communications, 17(1):348, January, 2026. Publisher: Nature Publishing Group![Variable temperature processing by plasmodesmata regulates robust bud dormancy release [link]](https://bibbase.org/img/filetypes/link.svg "link")
Paper doi abstract bibtex Dormancy is a key mechanism in perennial plants in boreal and temperate regions, protecting buds from winter damage by repressing precocious bud break before spring onset. How plants robustly time dormancy release under fluctuating environments remains unknown. Here, we show that, rather than simply sensing cold duration, buds leverage warm spikes to sense winter progression and time dormancy release. This timing mechanism is mediated by previously unrecognized regulation of plasmodesmata by warm spikes acting through tree ortholog of FLOWERING LOCUS T (FT1) and the gibberellic acid pathway. Our results reveal FT1 as a previously unrecognized, suppressor of callose levels and show that warm spikes repress cold induction of FT1 and GA pathway to suppress PD opening and dormancy release. Importantly, buds exhibit heterogeneity in bud break. This heterogeneity in bud break crucial for bet hedging is amplified under temperature fluctuations and is associated with the thermal responsiveness of plasmodesmata. Altogether, our work reveals dynamic plasmodesmata regulation as a crucial tissue-level mediator of variable temperature processing by buds, enabling robust adaptation of trees to seasonal changes.
@article{pandey_variable_2026,
title = {Variable temperature processing by plasmodesmata regulates robust bud dormancy release},
volume = {17},
copyright = {2026 The Author(s)},
issn = {2041-1723},
url = {https://www.nature.com/articles/s41467-025-67260-z},
doi = {10.1038/s41467-025-67260-z},
abstract = {Dormancy is a key mechanism in perennial plants in boreal and temperate regions, protecting buds from winter damage by repressing precocious bud break before spring onset. How plants robustly time dormancy release under fluctuating environments remains unknown. Here, we show that, rather than simply sensing cold duration, buds leverage warm spikes to sense winter progression and time dormancy release. This timing mechanism is mediated by previously unrecognized regulation of plasmodesmata by warm spikes acting through tree ortholog of FLOWERING LOCUS T (FT1) and the gibberellic acid pathway. Our results reveal FT1 as a previously unrecognized, suppressor of callose levels and show that warm spikes repress cold induction of FT1 and GA pathway to suppress PD opening and dormancy release. Importantly, buds exhibit heterogeneity in bud break. This heterogeneity in bud break crucial for bet hedging is amplified under temperature fluctuations and is associated with the thermal responsiveness of plasmodesmata. Altogether, our work reveals dynamic plasmodesmata regulation as a crucial tissue-level mediator of variable temperature processing by buds, enabling robust adaptation of trees to seasonal changes.},
language = {en},
number = {1},
urldate = {2026-01-16},
journal = {Nature Communications},
author = {Pandey, Shashank K. and Moraes, Tatiana S. and Nair, Aswin and Aryal, Bibek and Azeez, Abdul and Miskolczi, Pal and Maucort, Guillaume and Cordelières, Fabrice P. and Brocard, Lysiane and Davis, Gwendolyn V. and Dromiack, Hannah and Khanapurkar, Swanand and Walker, Sara I. and Bassel, George W. and Bayer, Emmanuelle M. and Bhalerao, Rishikesh P.},
month = jan,
year = {2026},
note = {Publisher: Nature Publishing Group},
keywords = {Plant molecular biology, Plant physiology, Shoot apical meristem},
pages = {348},
}
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