Interpretation of Subgroup Results in Clinical Trial Publications: Insights from a Survey of Medical Specialists in Ontario, Canada. Parker, A. B. & Naylor, C. D. Am Heart J, 151:580-588, 2006.
doi  bibtex   
@article{par06int,
  title = {Interpretation of Subgroup Results in Clinical Trial Publications: {{Insights}} from a Survey of Medical Specialists in {{Ontario}}, {{Canada}}},
  volume = {151},
  journal = {Am Heart J},
  doi = {10.1016/j.ahj.2005.05.002},
  author = {Parker, Andrea B. and Naylor, C. David},
  year = {2006},
  keywords = {teaching-mds,rct,subgroup-analysis},
  pages = {580-588},
  citeulike-article-id = {13265463},
  citeulike-linkout-0 = {http://dx.doi.org/10.1016/j.ahj.2005.05.002},
  posted-at = {2014-07-14 14:09:57},
  priority = {0},
  annote = {Survey of 435 physicians;many would exclude subgroup if no treatment benefit was shown even though the overall trial was positive;with overall harm when a subgroup showed benefit many would still use the drug;with overall null effect and positive interaction, many would adopt the new treatment;huge effect of academic appointment, devoting more time to research, formal training in research methodology;for those, many more demanded a significant interaction}
}

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