Health-related quality of life and its determinants in children and adolescents born with oesophageal atresia. Peetsold, M. G., Heij, H. A., Deurloo, J. A., & Gemke, R. J. B. J. Acta Paediatrica (Oslo, Norway: 1992), 99(3):411–417, March, 2010.
doi  abstract   bibtex   
AIM: Following surgical correction in the neonatal period, patients born with oesophageal atresia have significant co-morbidity, particularly in childhood. This study evaluates health-related quality of life and its determinants such as concomitant anomalies and the presence of respiratory and/or gastro-intestinal symptoms 6-18 years after repair of oesophageal atresia. METHODS: Parents of 24 patients with oesophageal atresia completed the child health questionnaire for parents and 37 patients completed the child form. Gastro-intestinal symptoms were assessed by a validated standardized reflux questionnaire. Results were compared with a healthy reference population. RESULTS: Parents as well as patients themselves scored significantly lower on the domain general health perception. According to parents, general health perception was negatively affected by age at follow-up and concomitant anomalies. Patients reported that reflux symptoms reduced general health perception. CONCLUSION: In this first study describing health-related quality of life in children and adolescents born with oesophageal atresia, we demonstrated that general health remains impaired because of a high incidence of concomitant anomalies and gastrointestinal symptoms in patients with oesophageal atresia when compared with the healthy reference population.
@article{peetsold_health-related_2010,
	title = {Health-related quality of life and its determinants in children and adolescents born with oesophageal atresia},
	volume = {99},
	issn = {1651-2227},
	doi = {10.1111/j.1651-2227.2009.01579.x},
	abstract = {AIM: Following surgical correction in the neonatal period, patients born with oesophageal atresia have significant co-morbidity, particularly in childhood. This study evaluates health-related quality of life and its determinants such as concomitant anomalies and the presence of respiratory and/or gastro-intestinal symptoms 6-18 years after repair of oesophageal atresia.
METHODS: Parents of 24 patients with oesophageal atresia completed the child health questionnaire for parents and 37 patients completed the child form. Gastro-intestinal symptoms were assessed by a validated standardized reflux questionnaire. Results were compared with a healthy reference population.
RESULTS: Parents as well as patients themselves scored significantly lower on the domain general health perception. According to parents, general health perception was negatively affected by age at follow-up and concomitant anomalies. Patients reported that reflux symptoms reduced general health perception.
CONCLUSION: In this first study describing health-related quality of life in children and adolescents born with oesophageal atresia, we demonstrated that general health remains impaired because of a high incidence of concomitant anomalies and gastrointestinal symptoms in patients with oesophageal atresia when compared with the healthy reference population.},
	language = {eng},
	number = {3},
	journal = {Acta Paediatrica (Oslo, Norway: 1992)},
	author = {Peetsold, M. G. and Heij, H. A. and Deurloo, J. A. and Gemke, R. J. B. J.},
	month = mar,
	year = {2010},
	keywords = {Adolescent, Case-Control Studies, Child, Comorbidity, Esophageal Atresia, Female, Follow-Up Studies, Gastroesophageal Reflux, Health Status, Health Surveys, Humans, Male, Outcome Assessment, Health Care, Parents, Quality of Life, Regression Analysis, Surveys and Questionnaires},
	pages = {411--417},
}

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