Exploring the world of small proteins in plant biology and bioengineering. Petri, L., Van Humbeeck, A., Niu, H., Ter Waarbeek, C., Edwards, A., Chiurazzi, M. J., Vittozzi, Y., & Wenkel, S. Trends in Genetics, October, 2024. Paper doi abstract bibtex Small proteins are ubiquitous in all kingdoms of life. MicroProteins, initially characterized as small proteins with protein interaction domains that enable them to interact with larger multidomain proteins, frequently modulate the function of these proteins. The study of these small proteins has contributed to a greater comprehension of protein regulation. In addition to sequence homology, sequence-divergent small proteins have the potential to function as microProtein mimics, binding to structurally related proteins. Moreover, a multitude of other small proteins encoded by short open reading frames (sORFs) and peptides, derived from diverse sources such as long noncoding RNAs (lncRNAs) and miRNAs, contribute to a variety of biological processes. The potential of small proteins is evident, offering promising avenues for bioengineering that could revolutionize crop performance and reduce reliance on agrochemicals in future agriculture.
@article{petri_exploring_2024,
title = {Exploring the world of small proteins in plant biology and bioengineering},
issn = {0168-9525},
url = {https://www.sciencedirect.com/science/article/pii/S0168952524002129},
doi = {10.1016/j.tig.2024.09.004},
abstract = {Small proteins are ubiquitous in all kingdoms of life. MicroProteins, initially characterized as small proteins with protein interaction domains that enable them to interact with larger multidomain proteins, frequently modulate the function of these proteins. The study of these small proteins has contributed to a greater comprehension of protein regulation. In addition to sequence homology, sequence-divergent small proteins have the potential to function as microProtein mimics, binding to structurally related proteins. Moreover, a multitude of other small proteins encoded by short open reading frames (sORFs) and peptides, derived from diverse sources such as long noncoding RNAs (lncRNAs) and miRNAs, contribute to a variety of biological processes. The potential of small proteins is evident, offering promising avenues for bioengineering that could revolutionize crop performance and reduce reliance on agrochemicals in future agriculture.},
urldate = {2024-10-18},
journal = {Trends in Genetics},
author = {Petri, Louise and Van Humbeeck, Anne and Niu, Huanying and Ter Waarbeek, Casper and Edwards, Ashleigh and Chiurazzi, Maurizio Junior and Vittozzi, Ylenia and Wenkel, Stephan},
month = oct,
year = {2024},
keywords = {lncRNA, microProteins, sORFs, transcription factor},
}
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