@article{pharkya2006optimization,
  title={An optimization framework for identifying reaction activation/inhibition or elimination candidates for overproduction in microbial systems},
  author={Pharkya, Priti and Maranas, Costas D},
  journal={Metabolic engineering},
  volume={8},
  number={1},
  pages={1--13},
  year={2006},
  publisher={Elsevier}
}

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