{"_id":"5qbbSNQkJ2qZ7xGHD","bibbaseid":"phillips-patrickcphillips-fromcomplextraitstocomplexalleles-1999","downloads":0,"creationDate":"2017-06-19T14:46:33.710Z","title":"From complex traits to complex alleles","author_short":["Phillips, P., C.","Patrick C. Phillips"],"year":1999,"bibtype":"article","biburl":null,"bibdata":{"title":"From complex traits to complex alleles","type":"article","year":"1999","identifiers":"[object Object]","keywords":"*Alleles,*Chromosome Mapping,*Genes,*Genetic Heterogeneity,*Quantitative Trait,Animal,Drosophila melanogaster/*genetics/physiology,Evolution,Female,Genetic Diseases,Human,Inborn/genetics,Infertility,Insect,Male,Male/genetics,Membrane Proteins/genetics/physiology,Non-P.H.S.,P.H.S.,Phenotype,Polymorphism (Genetics),Support,U.S. Gov't","pages":"6-8","volume":"15","id":"b6a2aaaa-b35d-3d77-ba5c-0930dbe055a9","created":"2017-06-19T13:41:59.662Z","file_attached":"true","profile_id":"de68dde1-2ff3-3a4e-a214-ef424d0c7646","group_id":"b2078731-0913-33b9-8902-a53629a24e83","last_modified":"2017-06-19T13:41:59.802Z","tags":"02/11/15","read":false,"starred":false,"authored":false,"confirmed":"true","hidden":false,"source_type":"Journal Article","notes":"<m:note> <m:bold>From Duplicate 2 ( </m:bold> <m:bold> </m:bold><m:bold><m:italic>From complex traits to complex alleles</m:italic></m:bold><m:bold> </m:bold> <m:bold> - Phillips, P C )<m:linebreak/> </m:bold> <m:linebreak/>eng<m:linebreak/>Journal Article<m:linebreak/>Review<m:linebreak/>Review, Tutorial<m:linebreak/> <m:linebreak/> </m:note>","abstract":"Several recent studies using natural populations of Drosophila show that one must be very careful when sorting among the large number of molecular polymorphisms found at most loci to identify the nucleotide changes responsible for phenotypic variation in complex traits. Indeed, several mutations within a single allele can interact to generate the overall observed effect. The results are instructive both for those interested in the genetics of evolutionary change and for those attempting to ferret out the genetic basis of complex human diseases.","bibtype":"article","author":"Phillips, Patric C and Patrick C. 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Indeed, several mutations within a single allele can interact to generate the overall observed effect. The results are instructive both for those interested in the genetics of evolutionary change and for those attempting to ferret out the genetic basis of complex human diseases.},\n bibtype = {article},\n author = {Phillips, Patric C and Patrick C. Phillips, undefined},\n journal = {Trends in genetics},\n number = {1}\n}","author_short":["Phillips, P., C.","Patrick C. 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