Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection. Pokorski, J. K, Nam, J., Vega, R. a, Mirkin, C. a, & Appella, D. H Chemical communications (Cambridge, England), April, 2005. Paper doi abstract bibtex trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.
@article{Pokorski2005,
title = {Cyclopentane-modified {PNA} improves the sensitivity of nanoparticle-based scanometric {DNA} detection.},
issn = {1359-7345},
url = {http://www.ncbi.nlm.nih.gov/pubmed/15846413},
doi = {10.1039/b418383e},
abstract = {trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.},
number = {16},
journal = {Chemical communications (Cambridge, England)},
author = {Pokorski, Jonathan K and Nam, Jwa-Min and Vega, Rafael a and Mirkin, Chad a and Appella, Daniel H},
month = apr,
year = {2005},
pmid = {15846413},
keywords = {\#nosource, Antigens, Bacterial, Bacterial Toxins, Bacterial Toxins: genetics, Bacterial: genetics, Base Pair Mismatch, Cyclopentanes, Cyclopentanes: chemistry, DNA, DNA: analysis, DNA: genetics, Molecular Structure, Nanoparticles, Nanoparticles: chemistry, Oligonucleotide Array Sequence Analysis, Oligonucleotide Array Sequence Analysis: methods, Oligonucleotide Probes, Peptide Nucleic Acids, Peptide Nucleic Acids: chemistry, Sensitivity and Specificity},
pages = {2101--3},
}
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