A framework for designing delivery systems. Poon, W., Kingston, B. R., Ouyang, B., Ngo, W., & Chan, W. C. W. Nat. Nanotechnol., 15(10):819–829, October, 2020. Bandiera_abtest: a Cg_type: Nature Research Journals Number: 10 Primary_atype: Reviews Publisher: Nature Publishing Group Subject_term: Biomedical engineering;Nanobiotechnology;Nanomedicine;Nanoscale materials Subject_term_id: biomedical-engineering;nanobiotechnology;nanomedicine;nanoscale-materialsPaper Paper doi abstract bibtex 5 downloads The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing and treating patients. Nanomaterials are promising vehicles to transport agents that include drugs, contrast agents, immunotherapies and gene editors. They can be engineered to have different physical and chemical properties that influence their interactions with their biological environments and delivery destinations. In this Review Article, we discuss nanoparticle delivery systems and how the biology of disease should inform their design. We propose developing a framework for building optimal delivery systems that uses nanoparticle–biological interaction data and computational analyses to guide future nanomaterial designs and delivery strategies.
@article{poon_framework_2020,
title = {A framework for designing delivery systems},
volume = {15},
copyright = {2020 Springer Nature Limited},
issn = {1748-3395},
url = {https://www.nature.com/articles/s41565-020-0759-5},
doi = {10.1038/s41565-020-0759-5},
abstract = {The delivery of medical agents to a specific diseased tissue or cell is critical for diagnosing and treating patients. Nanomaterials are promising vehicles to transport agents that include drugs, contrast agents, immunotherapies and gene editors. They can be engineered to have different physical and chemical properties that influence their interactions with their biological environments and delivery destinations. In this Review Article, we discuss nanoparticle delivery systems and how the biology of disease should inform their design. We propose developing a framework for building optimal delivery systems that uses nanoparticle–biological interaction data and computational analyses to guide future nanomaterial designs and delivery strategies.},
language = {en},
number = {10},
urldate = {2021-11-06},
journal = {Nat. Nanotechnol.},
author = {Poon, Wilson and Kingston, Benjamin R. and Ouyang, Ben and Ngo, Wayne and Chan, Warren C. W.},
month = oct,
year = {2020},
note = {Bandiera\_abtest: a
Cg\_type: Nature Research Journals
Number: 10
Primary\_atype: Reviews
Publisher: Nature Publishing Group
Subject\_term: Biomedical engineering;Nanobiotechnology;Nanomedicine;Nanoscale materials
Subject\_term\_id: biomedical-engineering;nanobiotechnology;nanomedicine;nanoscale-materials},
keywords = {Biomedical engineering, Nanobiotechnology, Nanomedicine, Nanoscale materials},
pages = {819--829},
file = {Full Text PDF:files/1795/Poon et al. - 2020 - A framework for designing delivery systems.pdf:application/pdf;Snapshot:files/1796/s41565-020-0759-5.html:text/html},
url_Paper = {https://inbs.med.utoronto.ca/wp-content/uploads/2022/01/Poon-et-al.-2020-A-framework-for-designing-delivery-systems.pdf}
}
Downloads: 5
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