@article{ Poppe2005b,
  author    = {Bruce Poppe and Nurten Yigit and Barbara De Moerloose and Anne De Paepe and Yves Benoit and Frank Speleman},
  title     = {HOXA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS.},
  journal   = {Cancer genetics and cytogenetics}, 
  abstract   = {We describe the molecular characterization of a t(7;9)(p15;q34) found in a 15-month-old female patient, diagnosed with refractory anemia with excess blasts in transformation (RAEBt), in progression to acute myeloid leukemia (AML) M7. Molecular characterization of the 7p15 breakpoint showed that this was localized within a fully sequenced PAC clone RP1-170O19 containing the HOXA4 to HOXA13 genes and the EVX1 gene. The 9q34 breakpoint was mapped distal to ABL1 and proximal to NOTCH1 excluding their involvement as fusion gene partners. Our findings suggest a causal role for HOXA genes in childhood myelodysplasia and warrant investigation of this locus in a larger series of patients.},
  issn   = {0165-4608},
  month   = {October},
  pages   = {82--4},
  volume   = {162},
  number   = {1},
  url   = {http://www.ncbi.nlm.nih.gov/pubmed/16157206} ,
  year   = {2005}
}

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