@Article{Prinz2004,
  author   = {Astrid A Prinz and Dirk Bucher and Eve Marder},
  journal  = {Nat Neurosci},
  title    = {Similar network activity from disparate circuit parameters.},
  year     = {2004},
  number   = {12},
  pages    = {1345-52},
  volume   = {7},
  abstract = {It is often assumed that cellular and synaptic properties need to
	be regulated to specific values to allow a neuronal network to function
	properly. To determine how tightly neuronal properties and synaptic
	strengths need to be tuned to produce a given network output, we
	simulated more than 20 million versions of a three-cell model of
	the pyloric network of the crustacean stomatogastric ganglion using
	different combinations of synapse strengths and neuron properties.
	We found that virtually indistinguishable network activity can arise
	from widely disparate sets of underlying mechanisms, suggesting that
	there could be considerable animal-to-animal variability in many
	of the parameters that control network activity, and that many different
	combinations of synaptic strengths and intrinsic membrane properties
	can be consistent with appropriate network performance.},
  doi      = {10.1038/nn1352},
  keywords = {Action Potentials, Animals, Comparative Study, Crustacea, Nerve Net, Neurons, Research Support, Non-U.S. Gov't, U.S. Gov't, P.H.S., Synapses, 15643435},
}

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