Matrix-assisted laser desorption ion trap mass spectrometry: Efficient trapping and ejection of ions. Qin, J. & Chait, B., T. Analytical Chemistry, 68(13):2102-2107, 1996.
Matrix-assisted laser desorption ion trap mass spectrometry: Efficient trapping and ejection of ions [link]Website  abstract   bibtex   
The present paper explores the coupling of a matrix-assisted laser desorption/ionization (MALDI) ion source with an ion trap mass analyzer, with particular emphasis on the development of methods for improving the efficiency of ion trapping and ejection, A technique is described for directly measuring, for the first time, the trapping efficiency of peptide ions produced in a remote external MALDI ion source. The technique was used to devise an improved scheme for trapping, which yielded efficiencies as high as 39%. An improved understanding of the resonant ejection process led us to a new resonant ejection parameter set that increased the ejection efficiency by 1 order of magnitude over more conventionally used parameter sets and allowed for marked improvements in the mass resolution of ions with m/z > 2500, The presently described improvements in the efficiencies of ion trapping and ejection together with improved methods for isolating and fragmenting ions (Qin, J.; Chait, B. T. Anal. Chem., following article in this issue) lay the foundation for highly sensitive MALDI ion trap mass spectrometry of proteins (Qin, J.; et al. Anal. Chem. 1996, 68, 1784-1791).
@article{
 title = {Matrix-assisted laser desorption ion trap mass spectrometry: Efficient trapping and ejection of ions},
 type = {article},
 year = {1996},
 identifiers = {[object Object]},
 keywords = {ionization,peptides,proteins},
 pages = {2102-2107},
 volume = {68},
 websites = {<Go to ISI>://A1996UW36700024},
 id = {7787e0db-e167-362a-8790-97bf8b179844},
 created = {2015-05-08T02:32:01.000Z},
 file_attached = {false},
 profile_id = {f8c267c4-4c39-31dc-80fa-3a9691373386},
 group_id = {63e349d6-2c70-3938-9e67-2f6483f6cbab},
 last_modified = {2015-05-08T12:53:40.000Z},
 read = {false},
 starred = {false},
 authored = {false},
 confirmed = {true},
 hidden = {false},
 source_type = {Journal Article},
 language = {English},
 notes = {Uw367<br/>Times Cited:32<br/>Cited References Count:21},
 abstract = {The present paper explores the coupling of a matrix-assisted laser desorption/ionization (MALDI) ion source with an ion trap mass analyzer, with particular emphasis on the development of methods for improving the efficiency of ion trapping and ejection, A technique is described for directly measuring, for the first time, the trapping efficiency of peptide ions produced in a remote external MALDI ion source. The technique was used to devise an improved scheme for trapping, which yielded efficiencies as high as 39%. An improved understanding of the resonant ejection process led us to a new resonant ejection parameter set that increased the ejection efficiency by 1 order of magnitude over more conventionally used parameter sets and allowed for marked improvements in the mass resolution of ions with m/z > 2500, The presently described improvements in the efficiencies of ion trapping and ejection together with improved methods for isolating and fragmenting ions (Qin, J.; Chait, B. T. Anal. Chem., following article in this issue) lay the foundation for highly sensitive MALDI ion trap mass spectrometry of proteins (Qin, J.; et al. Anal. Chem. 1996, 68, 1784-1791).},
 bibtype = {article},
 author = {Qin, J and Chait, B T},
 journal = {Analytical Chemistry},
 number = {13}
}

Downloads: 0