Solution structure of a pyrimidine·purine·pyrimidine DNA triplex containing T·AT, C+ ·GC and G·TA triples. Radhakrishnan, I. & Patel, D. J Structure, 2(1):17–32, January, 1994.
Paper doi abstract bibtex Under certain conditions, homopyrimidine oligonucleotides can bind to complementary homopurine sequences in homopurine-homopyrimidine segments of duplex DNA to form triple helical structures. Besides having biological implications in vivo, this property has been exploited in molecular biology applications. This approach is limited by a lack of knowledge about the recognition by the third strand of pyrimidine residues in Watson-Crick base pairs.
@article{Radhakrishnan1994,
title = {Solution structure of a pyrimidine·purine·pyrimidine {DNA} triplex containing {T}·{AT}, {C}+ ·{GC} and {G}·{TA} triples},
volume = {2},
issn = {09692126},
url = {http://linkinghub.elsevier.com/retrieve/pii/S0969212600000058 http://www.ncbi.nlm.nih.gov/pubmed/8075980},
doi = {10.1016/S0969-2126(00)00005-8},
abstract = {Under certain conditions, homopyrimidine oligonucleotides can bind to complementary homopurine sequences in homopurine-homopyrimidine segments of duplex DNA to form triple helical structures. Besides having biological implications in vivo, this property has been exploited in molecular biology applications. This approach is limited by a lack of knowledge about the recognition by the third strand of pyrimidine residues in Watson-Crick base pairs.},
number = {1},
journal = {Structure},
author = {Radhakrishnan, Ishwar and Patel, Dinshaw J},
month = jan,
year = {1994},
pmid = {8075980},
keywords = {\#nosource, Base Composition, Base Sequence, DNA, DNA: chemistry, Macromolecular Substances, Magnetic Resonance Spectroscopy, Magnetic Resonance Spectroscopy: methods, Mechanical, Models, Molecular, Molecular Sequence Data, Nucleic Acid Conformation, Oligodeoxyribonucleotides, Oligodeoxyribonucleotides: chemical synthesis, Oligodeoxyribonucleotides: chemistry, Purines, Pyrimidines, Solutions, Stress},
pages = {17--32},
}
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