The relationship between basal cell epithelioma and seborrheic keratosis. A study of 60 cases. Rao, B. K., Freeman, R. G., Poulos, E. G., Arbesfeld, L., & Rendon, M. J Dermatol Surg Oncol, 20(11):761–4, November, 1994.
The relationship between basal cell epithelioma and seborrheic keratosis. A study of 60 cases [link]Paper  doi  abstract   bibtex   
BACKGROUND: Various skin tumors can be seen rarely in association with seborrheic keratosis. We present 60 cases of seborrheic keratosis related to a basal cell epithelioma in the same specimen. OBJECTIVE: To report association of basal cell epithelioma with seborrheic keratosis and discuss the possibility of malignant change in seborrheic keratosis. METHODS: Sixty cases of seborrheic keratosis associated with basal cell epithelioma were studied. Tissues were fixed in neutral buffered formalin, processed, and stained with standard hematoxylin and eosin techniques. RESULTS: Histological evaluation showed a seborrheic keratosis associated with basal cell epithelioma in all of the cases. Basal cell epithelioma was attached with seborrheic keratosis in a majority of the cases (40/60) and appeared to represent a part of the same tumor. Both tumors were lying adjacent to each other in the rest of the cases (20/60). CONCLUSION: Malignant change in seborrheic keratosis is controversial. We recommend the histological evaluation of seborrheic keratosis especially when inflamed or atypical in appearance. This should not be taken as a mandate for pathological evaluation or for treatment of every seborrheic keratosis as though it was potentially malignant.
@article{rao_relationship_1994,
	title = {The relationship between basal cell epithelioma and seborrheic keratosis. {A} study of 60 cases},
	volume = {20},
	copyright = {All rights reserved},
	issn = {0148-0812 (Print) 0148-0812 (Linking)},
	url = {https://www.ncbi.nlm.nih.gov/pubmed/7962939},
	doi = {10.1111/j.1524-4725.1994.tb03201.x},
	abstract = {BACKGROUND: Various skin tumors can be seen rarely in association with seborrheic keratosis. We present 60 cases of seborrheic keratosis related to a basal cell epithelioma in the same specimen. OBJECTIVE: To report association of basal cell epithelioma with seborrheic keratosis and discuss the possibility of malignant change in seborrheic keratosis. METHODS: Sixty cases of seborrheic keratosis associated with basal cell epithelioma were studied. Tissues were fixed in neutral buffered formalin, processed, and stained with standard hematoxylin and eosin techniques. RESULTS: Histological evaluation showed a seborrheic keratosis associated with basal cell epithelioma in all of the cases. Basal cell epithelioma was attached with seborrheic keratosis in a majority of the cases (40/60) and appeared to represent a part of the same tumor. Both tumors were lying adjacent to each other in the rest of the cases (20/60). CONCLUSION: Malignant change in seborrheic keratosis is controversial. We recommend the histological evaluation of seborrheic keratosis especially when inflamed or atypical in appearance. This should not be taken as a mandate for pathological evaluation or for treatment of every seborrheic keratosis as though it was potentially malignant.},
	number = {11},
	journal = {J Dermatol Surg Oncol},
	author = {Rao, B. K. and Freeman, R. G. and Poulos, E. G. and Arbesfeld, L. and Rendon, M.},
	month = nov,
	year = {1994},
	keywords = {Adult, Aged, Aged, 80 and over, Carcinoma, Basal Cell/*complications/pathology, Cell Transformation, Neoplastic, Female, Humans, Keratosis, Seborrheic/*complications/pathology, Male, Middle Aged, Skin Neoplasms/*complications/pathology},
	pages = {761--4},
}

Downloads: 0