Role of VivaScope 2500 ex vivo confocal microscopy in skin pathology: Advantages, limitations, and future prospects. Razi, S., Ouellette, S., Khan, S., Oh, K. S., Truong, T. M., & Rao, B. K. Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 29(6):e13388, June, 2023.
doi  abstract   bibtex   
BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis. AIMS: To evaluate the current state of EVCM utilization. MATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology. RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases. CONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.
@article{razi_role_2023,
	title = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology: {Advantages}, limitations, and future prospects},
	volume = {29},
	issn = {1600-0846},
	shorttitle = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology},
	doi = {10.1111/srt.13388},
	abstract = {BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis.
AIMS: To evaluate the current state of EVCM utilization.
MATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.
RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.
CONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.},
	language = {eng},
	number = {6},
	journal = {Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)},
	author = {Razi, Shazli and Ouellette, Samantha and Khan, Samavia and Oh, Kei Shing and Truong, Thu M. and Rao, Babar K.},
	month = jun,
	year = {2023},
	pmid = {37357649},
	pmcid = {PMC10250963},
	keywords = {Carcinoma, Basal Cell, Humans, Male, Microscopy, Confocal, Mohs Surgery, Skin, Skin Neoplasms, fluorescence confocal microscope, frozen sectioning, fusion confocal microscope, pseudo staining, reflectance confocal microscopy},
	pages = {e13388},
}

Downloads: 0