Role of VivaScope 2500 ex vivo confocal microscopy in skin pathology: Advantages, limitations, and future prospects. Razi, S., Ouellette, S., Khan, S., Oh, K. S., Truong, T. M., & Rao, B. K. Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 29(6):e13388, June, 2023. doi abstract bibtex BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis. AIMS: To evaluate the current state of EVCM utilization. MATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology. RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases. CONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.
@article{razi_role_2023,
title = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology: {Advantages}, limitations, and future prospects},
volume = {29},
issn = {1600-0846},
shorttitle = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology},
doi = {10.1111/srt.13388},
abstract = {BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis.
AIMS: To evaluate the current state of EVCM utilization.
MATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.
RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.
CONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.},
language = {eng},
number = {6},
journal = {Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)},
author = {Razi, Shazli and Ouellette, Samantha and Khan, Samavia and Oh, Kei Shing and Truong, Thu M. and Rao, Babar K.},
month = jun,
year = {2023},
pmid = {37357649},
pmcid = {PMC10250963},
keywords = {Carcinoma, Basal Cell, Humans, Male, Microscopy, Confocal, Mohs Surgery, Skin, Skin Neoplasms, fluorescence confocal microscope, frozen sectioning, fusion confocal microscope, pseudo staining, reflectance confocal microscopy},
pages = {e13388},
}
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AIMS: To evaluate the current state of EVCM utilization. MATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology. RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases. CONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.","language":"eng","number":"6","journal":"Skin research and technology: official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)","author":[{"propositions":[],"lastnames":["Razi"],"firstnames":["Shazli"],"suffixes":[]},{"propositions":[],"lastnames":["Ouellette"],"firstnames":["Samantha"],"suffixes":[]},{"propositions":[],"lastnames":["Khan"],"firstnames":["Samavia"],"suffixes":[]},{"propositions":[],"lastnames":["Oh"],"firstnames":["Kei","Shing"],"suffixes":[]},{"propositions":[],"lastnames":["Truong"],"firstnames":["Thu","M."],"suffixes":[]},{"propositions":[],"lastnames":["Rao"],"firstnames":["Babar","K."],"suffixes":[]}],"month":"June","year":"2023","pmid":"37357649","pmcid":"PMC10250963","keywords":"Carcinoma, Basal Cell, Humans, Male, Microscopy, Confocal, Mohs Surgery, Skin, Skin Neoplasms, fluorescence confocal microscope, frozen sectioning, fusion confocal microscope, pseudo staining, reflectance confocal microscopy","pages":"e13388","bibtex":"@article{razi_role_2023,\n\ttitle = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology: {Advantages}, limitations, and future prospects},\n\tvolume = {29},\n\tissn = {1600-0846},\n\tshorttitle = {Role of {VivaScope} 2500 ex vivo confocal microscopy in skin pathology},\n\tdoi = {10.1111/srt.13388},\n\tabstract = {BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis.\nAIMS: To evaluate the current state of EVCM utilization.\nMATERIALS AND METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.\nRESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.\nCONCLUSION: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. 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