Adrenaline in Bronchial Asthma. Rees, H. A., Millar, J. S., & Donald, K. W. The Lancet, 290(7527):1164–1167, December, 1967.
Adrenaline in Bronchial Asthma [link]Paper  doi  abstract   bibtex   
Adrenaline given to chronic wheezy asthmatic patients relieved airway obstruction but not hypoxæmia. Voluntary hyperventilation in another group of asthmatic patients produced similar increases in PaO2 whether or not airway obstruction had been relieved. The hypoxæmia seemed to be related to disturbed ventilation-perfusion relationships, and it is important to realise that this hypoxæmia commonly persists despite considerable relief of airway obstruction by bronchodilator drugs.
@article{rees_adrenaline_1967,
	series = {Originally published as {Volume} 2, {Issue} 7527},
	title = {Adrenaline in {Bronchial} {Asthma}},
	volume = {290},
	issn = {0140-6736},
	url = {http://www.sciencedirect.com/science/article/pii/S0140673667918892},
	doi = {10.1016/S0140-6736(67)91889-2},
	abstract = {Adrenaline given to chronic wheezy asthmatic patients relieved airway obstruction but not hypoxæmia. Voluntary hyperventilation in another group of asthmatic patients produced similar increases in PaO2 whether or not airway obstruction had been relieved. The hypoxæmia seemed to be related to disturbed ventilation-perfusion relationships, and it is important to realise that this hypoxæmia commonly persists despite considerable relief of airway obstruction by bronchodilator drugs.},
	number = {7527},
	urldate = {2014-09-29},
	journal = {The Lancet},
	author = {Rees, H. A. and Millar, J. S. and Donald, K. W.},
	month = dec,
	year = {1967},
	pages = {1164--1167},
}

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