@article{RN400,
   author = {Reyes, C. and Pistillo, A. and Fernández-Bertolín, S. and Recalde, M. and Roel, E. and Puente, D. and Sena, A. G. and Blacketer, C. and Lai, L. and Alshammari, T. M. and Ahmed, W. U. and Alser, O. and Alghoul, H. and Areia, C. and Dawoud, D. and Prats-Uribe, A. and Valveny, N. and de Maeztu, G. and Sorlí Redó, L. and Martinez Roldan, J. and Lopez Montesinos, I. and Schilling, L. M. and Golozar, A. and Reich, C. and Posada, J. D. and Shah, N. and You, S. C. and Lynch, K. E. and DuVall, S. L. and Matheny, M. E. and Nyberg, F. and Ostropolets, A. and Hripcsak, G. and Rijnbeek, P. R. and Suchard, M. A. and Ryan, P. and Kostka, K. and Duarte-Salles, T.},
   title = {Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study},
   journal = {BMJ Open},
   volume = {11},
   number = {12},
   pages = {e057632},
   note = {2044-6055 Reyes, Carlen Orcid: 0000-0001-8486-3265 Pistillo, Andrea Fernández-Bertolín, Sergio Recalde, Martina Roel, Elena Puente, Diana Sena, Anthony G Blacketer, Clair Lai, Lana Alshammari, Thamir M Ahmed, Waheed-Ui-Rahman Alser, Osaid Orcid: 0000-0001-6743-803x Alghoul, Heba Orcid: 0000-0001-8234-5843 Areia, Carlos Orcid: 0000-0002-4668-7069 Dawoud, Dalia Prats-Uribe, Albert Orcid: 0000-0003-1202-9153 Valveny, Neus de Maeztu, Gabriel Sorlí Redó, Luisa Martinez Roldan, Jordi Lopez Montesinos, Inmaculada Schilling, Lisa M Golozar, Asieh Reich, Christian Posada, Jose D Shah, Nigam You, Seng Chan Lynch, Kristine E DuVall, Scott L Matheny, Michael E Nyberg, Fredrik Ostropolets, Anna Hripcsak, George Rijnbeek, Peter R Orcid: 0000-0003-0621-1979 Suchard, Marc A Ryan, Patrick Kostka, Kristin Orcid: 0000-0003-2595-8736 Duarte-Salles, Talita Orcid: 0000-0002-8274-0357 R01 LM006910/LM/NLM NIH HHS/United States Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2021/12/24 BMJ Open. 2021 Dec 22;11(12):e057632. doi: 10.1136/bmjopen-2021-057632.},
   abstract = {OBJECTIVE: To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. DESIGN AND SETTING: This is a retrospective cohort study using 15 healthcare databases (primary and secondary electronic healthcare records, insurance and national claims data) from the USA, Europe and South Korea, standardised to the Observational Medical Outcomes Partnership common data model. Data were gathered from 1 March to 31 October 2020. PARTICIPANTS: Two non-mutually exclusive cohorts were defined: (1) individuals diagnosed with COVID-19 (diagnosed cohort) and (2) individuals hospitalised with COVID-19 (hospitalised cohort), and stratified by hypertension status. Follow-up was from COVID-19 diagnosis/hospitalisation to death, end of the study period or 30 days. OUTCOMES: Demographics, comorbidities and 30-day outcomes (hospitalisation and death for the 'diagnosed' cohort and adverse events and death for the 'hospitalised' cohort) were reported. RESULTS: We identified 2 851 035 diagnosed and 563 708 hospitalised patients with COVID-19. Hypertension was more prevalent in the latter (ranging across databases from 17.4% (95% CI 17.2 to 17.6) to 61.4% (95% CI 61.0 to 61.8) and from 25.6% (95% CI 24.6 to 26.6) to 85.9% (95% CI 85.2 to 86.6)). Patients in both cohorts with hypertension were predominantly >50 years old and female. Patients with hypertension were frequently diagnosed with obesity, heart disease, dyslipidaemia and diabetes. Compared with patients without hypertension, patients with hypertension in the COVID-19 diagnosed cohort had more hospitalisations (ranging from 1.3% (95% CI 0.4 to 2.2) to 41.1% (95% CI 39.5 to 42.7) vs from 1.4% (95% CI 0.9 to 1.9) to 15.9% (95% CI 14.9 to 16.9)) and increased mortality (ranging from 0.3% (95% CI 0.1 to 0.5) to 18.5% (95% CI 15.7 to 21.3) vs from 0.2% (95% CI 0.2 to 0.2) to 11.8% (95% CI 10.8 to 12.8)). Patients in the COVID-19 hospitalised cohort with hypertension were more likely to have acute respiratory distress syndrome (ranging from 0.1% (95% CI 0.0 to 0.2) to 65.6% (95% CI 62.5 to 68.7) vs from 0.1% (95% CI 0.0 to 0.2) to 54.7% (95% CI 50.5 to 58.9)), arrhythmia (ranging from 0.5% (95% CI 0.3 to 0.7) to 45.8% (95% CI 42.6 to 49.0) vs from 0.4% (95% CI 0.3 to 0.5) to 36.8% (95% CI 32.7 to 40.9)) and increased mortality (ranging from 1.8% (95% CI 0.4 to 3.2) to 25.1% (95% CI 23.0 to 27.2) vs from 0.7% (95% CI 0.5 to 0.9) to 10.9% (95% CI 10.4 to 11.4)) than patients without hypertension. CONCLUSIONS: COVID-19 patients with hypertension were more likely to suffer severe outcomes, hospitalisations and deaths compared with those without hypertension.},
   keywords = {*covid-19
COVID-19 Testing
Cohort Studies
Comorbidity
Female
Hospitalization
Humans
*Hypertension/epidemiology
Middle Aged
Retrospective Studies
SARS-CoV-2
Covid-19
epidemiology
hypertension ,
ISSN = 2044-6055 ,
DOI = 10.1136/bmjopen-2021-057632},
   year = {2021},
   type = {Journal Article}
}

{"_id":"CXAEps3TMuYgB59yn","bibbaseid":"reyes-pistillo-fernndezbertoln-recalde-roel-puente-sena-blacketer-etal-characteristicsandoutcomesofpatientswithcovid19withandwithoutprevalenthypertensionamultinationalcohortstudy-2021","author_short":["Reyes, C.","Pistillo, A.","Fernández-Bertolín, S.","Recalde, M.","Roel, E.","Puente, D.","Sena, A. G.","Blacketer, C.","Lai, L.","Alshammari, T. M.","Ahmed, W. U.","Alser, O.","Alghoul, H.","Areia, C.","Dawoud, D.","Prats-Uribe, A.","Valveny, N.","de Maeztu, G.","Sorlí Redó, L.","Martinez Roldan, J.","Lopez Montesinos, I.","Schilling, L. M.","Golozar, A.","Reich, C.","Posada, J. D.","Shah, N.","You, S. C.","Lynch, K. E.","DuVall, S. L.","Matheny, M. E.","Nyberg, F.","Ostropolets, A.","Hripcsak, G.","Rijnbeek, P. R.","Suchard, M. A.","Ryan, P.","Kostka, K.","Duarte-Salles, T."],"bibdata":{"bibtype":"article","type":"Journal Article","author":[{"propositions":[],"lastnames":["Reyes"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Pistillo"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Fernández-Bertolín"],"firstnames":["S."],"suffixes":[]},{"propositions":[],"lastnames":["Recalde"],"firstnames":["M."],"suffixes":[]},{"propositions":[],"lastnames":["Roel"],"firstnames":["E."],"suffixes":[]},{"propositions":[],"lastnames":["Puente"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Sena"],"firstnames":["A.","G."],"suffixes":[]},{"propositions":[],"lastnames":["Blacketer"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Lai"],"firstnames":["L."],"suffixes":[]},{"propositions":[],"lastnames":["Alshammari"],"firstnames":["T.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Ahmed"],"firstnames":["W.","U."],"suffixes":[]},{"propositions":[],"lastnames":["Alser"],"firstnames":["O."],"suffixes":[]},{"propositions":[],"lastnames":["Alghoul"],"firstnames":["H."],"suffixes":[]},{"propositions":[],"lastnames":["Areia"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Dawoud"],"firstnames":["D."],"suffixes":[]},{"propositions":[],"lastnames":["Prats-Uribe"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Valveny"],"firstnames":["N."],"suffixes":[]},{"propositions":["de"],"lastnames":["Maeztu"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Sorlí","Redó"],"firstnames":["L."],"suffixes":[]},{"propositions":[],"lastnames":["Martinez","Roldan"],"firstnames":["J."],"suffixes":[]},{"propositions":[],"lastnames":["Lopez","Montesinos"],"firstnames":["I."],"suffixes":[]},{"propositions":[],"lastnames":["Schilling"],"firstnames":["L.","M."],"suffixes":[]},{"propositions":[],"lastnames":["Golozar"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Reich"],"firstnames":["C."],"suffixes":[]},{"propositions":[],"lastnames":["Posada"],"firstnames":["J.","D."],"suffixes":[]},{"propositions":[],"lastnames":["Shah"],"firstnames":["N."],"suffixes":[]},{"propositions":[],"lastnames":["You"],"firstnames":["S.","C."],"suffixes":[]},{"propositions":[],"lastnames":["Lynch"],"firstnames":["K.","E."],"suffixes":[]},{"propositions":[],"lastnames":["DuVall"],"firstnames":["S.","L."],"suffixes":[]},{"propositions":[],"lastnames":["Matheny"],"firstnames":["M.","E."],"suffixes":[]},{"propositions":[],"lastnames":["Nyberg"],"firstnames":["F."],"suffixes":[]},{"propositions":[],"lastnames":["Ostropolets"],"firstnames":["A."],"suffixes":[]},{"propositions":[],"lastnames":["Hripcsak"],"firstnames":["G."],"suffixes":[]},{"propositions":[],"lastnames":["Rijnbeek"],"firstnames":["P.","R."],"suffixes":[]},{"propositions":[],"lastnames":["Suchard"],"firstnames":["M.","A."],"suffixes":[]},{"propositions":[],"lastnames":["Ryan"],"firstnames":["P."],"suffixes":[]},{"propositions":[],"lastnames":["Kostka"],"firstnames":["K."],"suffixes":[]},{"propositions":[],"lastnames":["Duarte-Salles"],"firstnames":["T."],"suffixes":[]}],"title":"Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study","journal":"BMJ Open","volume":"11","number":"12","pages":"e057632","note":"2044-6055 Reyes, Carlen Orcid: 0000-0001-8486-3265 Pistillo, Andrea Fernández-Bertolín, Sergio Recalde, Martina Roel, Elena Puente, Diana Sena, Anthony G Blacketer, Clair Lai, Lana Alshammari, Thamir M Ahmed, Waheed-Ui-Rahman Alser, Osaid Orcid: 0000-0001-6743-803x Alghoul, Heba Orcid: 0000-0001-8234-5843 Areia, Carlos Orcid: 0000-0002-4668-7069 Dawoud, Dalia Prats-Uribe, Albert Orcid: 0000-0003-1202-9153 Valveny, Neus de Maeztu, Gabriel Sorlí Redó, Luisa Martinez Roldan, Jordi Lopez Montesinos, Inmaculada Schilling, Lisa M Golozar, Asieh Reich, Christian Posada, Jose D Shah, Nigam You, Seng Chan Lynch, Kristine E DuVall, Scott L Matheny, Michael E Nyberg, Fredrik Ostropolets, Anna Hripcsak, George Rijnbeek, Peter R Orcid: 0000-0003-0621-1979 Suchard, Marc A Ryan, Patrick Kostka, Kristin Orcid: 0000-0003-2595-8736 Duarte-Salles, Talita Orcid: 0000-0002-8274-0357 R01 LM006910/LM/NLM NIH HHS/United States Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2021/12/24 BMJ Open. 2021 Dec 22;11(12):e057632. doi: 10.1136/bmjopen-2021-057632.","abstract":"OBJECTIVE: To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. DESIGN AND SETTING: This is a retrospective cohort study using 15 healthcare databases (primary and secondary electronic healthcare records, insurance and national claims data) from the USA, Europe and South Korea, standardised to the Observational Medical Outcomes Partnership common data model. Data were gathered from 1 March to 31 October 2020. PARTICIPANTS: Two non-mutually exclusive cohorts were defined: (1) individuals diagnosed with COVID-19 (diagnosed cohort) and (2) individuals hospitalised with COVID-19 (hospitalised cohort), and stratified by hypertension status. Follow-up was from COVID-19 diagnosis/hospitalisation to death, end of the study period or 30 days. OUTCOMES: Demographics, comorbidities and 30-day outcomes (hospitalisation and death for the 'diagnosed' cohort and adverse events and death for the 'hospitalised' cohort) were reported. RESULTS: We identified 2 851 035 diagnosed and 563 708 hospitalised patients with COVID-19. Hypertension was more prevalent in the latter (ranging across databases from 17.4% (95% CI 17.2 to 17.6) to 61.4% (95% CI 61.0 to 61.8) and from 25.6% (95% CI 24.6 to 26.6) to 85.9% (95% CI 85.2 to 86.6)). Patients in both cohorts with hypertension were predominantly >50 years old and female. Patients with hypertension were frequently diagnosed with obesity, heart disease, dyslipidaemia and diabetes. Compared with patients without hypertension, patients with hypertension in the COVID-19 diagnosed cohort had more hospitalisations (ranging from 1.3% (95% CI 0.4 to 2.2) to 41.1% (95% CI 39.5 to 42.7) vs from 1.4% (95% CI 0.9 to 1.9) to 15.9% (95% CI 14.9 to 16.9)) and increased mortality (ranging from 0.3% (95% CI 0.1 to 0.5) to 18.5% (95% CI 15.7 to 21.3) vs from 0.2% (95% CI 0.2 to 0.2) to 11.8% (95% CI 10.8 to 12.8)). Patients in the COVID-19 hospitalised cohort with hypertension were more likely to have acute respiratory distress syndrome (ranging from 0.1% (95% CI 0.0 to 0.2) to 65.6% (95% CI 62.5 to 68.7) vs from 0.1% (95% CI 0.0 to 0.2) to 54.7% (95% CI 50.5 to 58.9)), arrhythmia (ranging from 0.5% (95% CI 0.3 to 0.7) to 45.8% (95% CI 42.6 to 49.0) vs from 0.4% (95% CI 0.3 to 0.5) to 36.8% (95% CI 32.7 to 40.9)) and increased mortality (ranging from 1.8% (95% CI 0.4 to 3.2) to 25.1% (95% CI 23.0 to 27.2) vs from 0.7% (95% CI 0.5 to 0.9) to 10.9% (95% CI 10.4 to 11.4)) than patients without hypertension. CONCLUSIONS: COVID-19 patients with hypertension were more likely to suffer severe outcomes, hospitalisations and deaths compared with those without hypertension.","keywords":"*covid-19 COVID-19 Testing Cohort Studies Comorbidity Female Hospitalization Humans *Hypertension/epidemiology Middle Aged Retrospective Studies SARS-CoV-2 Covid-19 epidemiology hypertension , ISSN = 2044-6055 , DOI = 10.1136/bmjopen-2021-057632","year":"2021","bibtex":"@article{RN400,\r\n author = {Reyes, C. and Pistillo, A. and Fernández-Bertolín, S. and Recalde, M. and Roel, E. and Puente, D. and Sena, A. G. and Blacketer, C. and Lai, L. and Alshammari, T. M. and Ahmed, W. U. and Alser, O. and Alghoul, H. and Areia, C. and Dawoud, D. and Prats-Uribe, A. and Valveny, N. and de Maeztu, G. and Sorlí Redó, L. and Martinez Roldan, J. and Lopez Montesinos, I. and Schilling, L. M. and Golozar, A. and Reich, C. and Posada, J. D. and Shah, N. and You, S. C. and Lynch, K. E. and DuVall, S. L. and Matheny, M. E. and Nyberg, F. and Ostropolets, A. and Hripcsak, G. and Rijnbeek, P. R. and Suchard, M. A. and Ryan, P. and Kostka, K. and Duarte-Salles, T.},\r\n title = {Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study},\r\n journal = {BMJ Open},\r\n volume = {11},\r\n number = {12},\r\n pages = {e057632},\r\n note = {2044-6055 Reyes, Carlen Orcid: 0000-0001-8486-3265 Pistillo, Andrea Fernández-Bertolín, Sergio Recalde, Martina Roel, Elena Puente, Diana Sena, Anthony G Blacketer, Clair Lai, Lana Alshammari, Thamir M Ahmed, Waheed-Ui-Rahman Alser, Osaid Orcid: 0000-0001-6743-803x Alghoul, Heba Orcid: 0000-0001-8234-5843 Areia, Carlos Orcid: 0000-0002-4668-7069 Dawoud, Dalia Prats-Uribe, Albert Orcid: 0000-0003-1202-9153 Valveny, Neus de Maeztu, Gabriel Sorlí Redó, Luisa Martinez Roldan, Jordi Lopez Montesinos, Inmaculada Schilling, Lisa M Golozar, Asieh Reich, Christian Posada, Jose D Shah, Nigam You, Seng Chan Lynch, Kristine E DuVall, Scott L Matheny, Michael E Nyberg, Fredrik Ostropolets, Anna Hripcsak, George Rijnbeek, Peter R Orcid: 0000-0003-0621-1979 Suchard, Marc A Ryan, Patrick Kostka, Kristin Orcid: 0000-0003-2595-8736 Duarte-Salles, Talita Orcid: 0000-0002-8274-0357 R01 LM006910/LM/NLM NIH HHS/United States Journal Article Observational Study Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. England 2021/12/24 BMJ Open. 2021 Dec 22;11(12):e057632. doi: 10.1136/bmjopen-2021-057632.},\r\n abstract = {OBJECTIVE: To characterise patients with and without prevalent hypertension and COVID-19 and to assess adverse outcomes in both inpatients and outpatients. DESIGN AND SETTING: This is a retrospective cohort study using 15 healthcare databases (primary and secondary electronic healthcare records, insurance and national claims data) from the USA, Europe and South Korea, standardised to the Observational Medical Outcomes Partnership common data model. Data were gathered from 1 March to 31 October 2020. PARTICIPANTS: Two non-mutually exclusive cohorts were defined: (1) individuals diagnosed with COVID-19 (diagnosed cohort) and (2) individuals hospitalised with COVID-19 (hospitalised cohort), and stratified by hypertension status. Follow-up was from COVID-19 diagnosis/hospitalisation to death, end of the study period or 30 days. OUTCOMES: Demographics, comorbidities and 30-day outcomes (hospitalisation and death for the 'diagnosed' cohort and adverse events and death for the 'hospitalised' cohort) were reported. RESULTS: We identified 2 851 035 diagnosed and 563 708 hospitalised patients with COVID-19. Hypertension was more prevalent in the latter (ranging across databases from 17.4% (95% CI 17.2 to 17.6) to 61.4% (95% CI 61.0 to 61.8) and from 25.6% (95% CI 24.6 to 26.6) to 85.9% (95% CI 85.2 to 86.6)). Patients in both cohorts with hypertension were predominantly >50 years old and female. Patients with hypertension were frequently diagnosed with obesity, heart disease, dyslipidaemia and diabetes. Compared with patients without hypertension, patients with hypertension in the COVID-19 diagnosed cohort had more hospitalisations (ranging from 1.3% (95% CI 0.4 to 2.2) to 41.1% (95% CI 39.5 to 42.7) vs from 1.4% (95% CI 0.9 to 1.9) to 15.9% (95% CI 14.9 to 16.9)) and increased mortality (ranging from 0.3% (95% CI 0.1 to 0.5) to 18.5% (95% CI 15.7 to 21.3) vs from 0.2% (95% CI 0.2 to 0.2) to 11.8% (95% CI 10.8 to 12.8)). Patients in the COVID-19 hospitalised cohort with hypertension were more likely to have acute respiratory distress syndrome (ranging from 0.1% (95% CI 0.0 to 0.2) to 65.6% (95% CI 62.5 to 68.7) vs from 0.1% (95% CI 0.0 to 0.2) to 54.7% (95% CI 50.5 to 58.9)), arrhythmia (ranging from 0.5% (95% CI 0.3 to 0.7) to 45.8% (95% CI 42.6 to 49.0) vs from 0.4% (95% CI 0.3 to 0.5) to 36.8% (95% CI 32.7 to 40.9)) and increased mortality (ranging from 1.8% (95% CI 0.4 to 3.2) to 25.1% (95% CI 23.0 to 27.2) vs from 0.7% (95% CI 0.5 to 0.9) to 10.9% (95% CI 10.4 to 11.4)) than patients without hypertension. CONCLUSIONS: COVID-19 patients with hypertension were more likely to suffer severe outcomes, hospitalisations and deaths compared with those without hypertension.},\r\n keywords = {*covid-19\r\nCOVID-19 Testing\r\nCohort Studies\r\nComorbidity\r\nFemale\r\nHospitalization\r\nHumans\r\n*Hypertension/epidemiology\r\nMiddle Aged\r\nRetrospective Studies\r\nSARS-CoV-2\r\nCovid-19\r\nepidemiology\r\nhypertension ,\r\nISSN = 2044-6055 ,\r\nDOI = 10.1136/bmjopen-2021-057632},\r\n year = {2021},\r\n type = {Journal Article}\r\n}\r\n\r\n","author_short":["Reyes, C.","Pistillo, A.","Fernández-Bertolín, S.","Recalde, M.","Roel, E.","Puente, D.","Sena, A. G.","Blacketer, C.","Lai, L.","Alshammari, T. M.","Ahmed, W. U.","Alser, O.","Alghoul, H.","Areia, C.","Dawoud, D.","Prats-Uribe, A.","Valveny, N.","de Maeztu, G.","Sorlí Redó, L.","Martinez Roldan, J.","Lopez Montesinos, I.","Schilling, L. M.","Golozar, A.","Reich, C.","Posada, J. D.","Shah, N.","You, S. C.","Lynch, K. E.","DuVall, S. L.","Matheny, M. E.","Nyberg, F.","Ostropolets, A.","Hripcsak, G.","Rijnbeek, P. R.","Suchard, M. A.","Ryan, P.","Kostka, K.","Duarte-Salles, T."],"key":"RN400","id":"RN400","bibbaseid":"reyes-pistillo-fernndezbertoln-recalde-roel-puente-sena-blacketer-etal-characteristicsandoutcomesofpatientswithcovid19withandwithoutprevalenthypertensionamultinationalcohortstudy-2021","role":"author","urls":{},"keyword":["*covid-19 COVID-19 Testing Cohort Studies Comorbidity Female Hospitalization Humans *Hypertension/epidemiology Middle Aged Retrospective Studies SARS-CoV-2 Covid-19 epidemiology hypertension","ISSN = 2044-6055","DOI = 10.1136/bmjopen-2021-057632"],"metadata":{"authorlinks":{}},"html":""},"bibtype":"article","biburl":"https://bibbase.org/network/files/qwipow2DJsAxqNp83","dataSources":["PJSqX8FMpCPRdw3CQ","qLDnCcKM9omXNrRY8","TB9sD3avjy7bNxfgS","vDmJPYmHEKAT3tMNL","PcZMFHooKwpboi2he","jZMXEeHTfokmisJDv"],"keywords":["*covid-19 covid-19 testing cohort studies comorbidity female hospitalization humans *hypertension/epidemiology middle aged retrospective studies sars-cov-2 covid-19 epidemiology hypertension","issn = 2044-6055","doi = 10.1136/bmjopen-2021-057632"],"search_terms":["characteristics","outcomes","patients","covid","without","prevalent","hypertension","multinational","cohort","study","reyes","pistillo","fernández-bertolín","recalde","roel","puente","sena","blacketer","lai","alshammari","ahmed","alser","alghoul","areia","dawoud","prats-uribe","valveny","de maeztu","sorlí redó","martinez roldan","lopez montesinos","schilling","golozar","reich","posada","shah","you","lynch","duvall","matheny","nyberg","ostropolets","hripcsak","rijnbeek","suchard","ryan","kostka","duarte-salles"],"title":"Characteristics and outcomes of patients with COVID-19 with and without prevalent hypertension: a multinational cohort study","year":2021}