Heavy metal resistance patterns of Frankia strains. Richards, J. W, Krumholz, G. D, Chval, M. S, & Tisa, L. S Applied and Environmental Microbiology, 68(2):923--927, February, 2002.
Heavy metal resistance patterns of Frankia strains [link]Paper  abstract   bibtex   
The sensitivity of 12 Frankia strains to heavy metals was determined by a growth inhibition assay. In general, all of the strains were sensitive to low concentrations (\textless0.5 mM) of Ag(1+), AsO(2)(1-), Cd(2+), SbO(2)(1-), and Ni(2+), but most of the strains were less sensitive to Pb(2+) (6 to 8 mM), CrO(4)(2-) (1.0 to 1.75 mM), AsO(4)(3-) (\textgreater50 mM), and SeO(2)(2-) (1.5 to 3.5 mM). While most strains were sensitive to 0.1 mM Cu(2+), four strains were resistant to elevated levels of Cu(2+) (2 to 5 mM and concentrations as high as 20 mM). The mechanism of SeO(2)(2-) resistance seems to involve reduction of the selenite oxyanion to insoluble elemental selenium, whereas Pb(2+) resistance and Cu(2+) resistance may involve sequestration or binding mechanisms. Indications of the resistance mechanisms for the other heavy metals were not as clear.
@article{richards_heavy_2002,
	title = {Heavy metal resistance patterns of {Frankia} strains},
	volume = {68},
	issn = {0099-2240},
	url = {http://www.ncbi.nlm.nih.gov/pubmed/11823237},
	abstract = {The sensitivity of 12 Frankia strains to heavy metals was determined by a growth inhibition assay. In general, all of the strains were sensitive to low concentrations ({\textless}0.5 mM) of Ag(1+), AsO(2)(1-), Cd(2+), SbO(2)(1-), and Ni(2+), but most of the strains were less sensitive to Pb(2+) (6 to 8 mM), CrO(4)(2-) (1.0 to 1.75 mM), AsO(4)(3-) ({\textgreater}50 mM), and SeO(2)(2-) (1.5 to 3.5 mM). While most strains were sensitive to 0.1 mM Cu(2+), four strains were resistant to elevated levels of Cu(2+) (2 to 5 mM and concentrations as high as 20 mM). The mechanism of SeO(2)(2-) resistance seems to involve reduction of the selenite oxyanion to insoluble elemental selenium, whereas Pb(2+) resistance and Cu(2+) resistance may involve sequestration or binding mechanisms. Indications of the resistance mechanisms for the other heavy metals were not as clear.},
	number = {2},
	urldate = {2009-10-30TZ},
	journal = {Applied and Environmental Microbiology},
	author = {Richards, Joel W and Krumholz, Glenn D and Chval, Matthew S and Tisa, Louis S},
	month = feb,
	year = {2002},
	pmid = {11823237},
	keywords = {Actinomycetales, Culture Media, Drug Resistance, Bacterial, Metals, Heavy, Microbial Sensitivity Tests},
	pages = {923--927}
}

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