Histology by Mass Spectrometry: Label-Free Tissue Characterization Obtained from High-Accuracy Bioanalytical Imaging. Römpp, A., Guenther, S., Schober, Y., Schulz, O., Takats, Z., Kummer, W., & Spengler, B. Angew Chem Int Ed, 49(22):3834–3838, Wiley Online Library, 2010. doi abstract bibtex Next-generation imaging mass spectrometry of biological tissue on the cellular level shows excellent agreement with histochemical evaluation whilst providing a much higher discrimination capacity based on label-free molecular information (see image of a mouse urinary bladder section).
@Article{roempp10histology,
author = {R{\"o}mpp, Andreas and Guenther, Sabine and Schober, Yvonne and Schulz, Oliver and Takats, Zoltan and Kummer, Wolfgang and Spengler, Bernhard},
title = {Histology by Mass Spectrometry: Label-Free Tissue Characterization Obtained from High-Accuracy Bioanalytical Imaging},
journal = {Angew Chem Int Ed},
year = {2010},
volume = {49},
number = {22},
pages = {3834--3838},
abstract = {Next-generation imaging mass spectrometry of biological tissue on the cellular level shows excellent agreement with histochemical evaluation whilst providing a much higher discrimination capacity based on label-free molecular information (see image of a mouse urinary bladder section).},
doi = {10.1002/anie.200905559},
file = {RoemppEtAl_HistologyMSLabelFreeTissueCharacterization_AngChemie_2010.pdf:2010/RoemppEtAl_HistologyMSLabelFreeTissueCharacterization_AngChemie_2010.pdf:PDF},
keywords = {accurate mass;histology;imaging;mass spectrometry;spatial resolution},
owner = {purva},
publisher = {Wiley Online Library},
timestamp = {2015.01.07},
}
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